| Entry |
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| Name |
isocitrate lyase;
isocitrase;
isocitritase;
isocitratase;
threo-Ds-isocitrate glyoxylate-lyase;
isocitrate glyoxylate-lyase
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| Class |
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
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| Sysname |
isocitrate glyoxylate-lyase (succinate-forming)
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| Reaction(IUBMB) |
isocitrate = succinate + glyoxylate [RN: R00479]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate [3].
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| History |
EC 4.1.3.1 created 1961
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| Pathway |
| ec00630 | Glyoxylate and dicarboxylate metabolism |
| ec01110 | Biosynthesis of secondary metabolites |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
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| Genes |
» show all
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| Reference |
1 |
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| Authors |
McFadden, B.A. and Howes, W.V. |
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| Title |
Crystallisation and some properties of isocitrate lyase from Pseudomonas indigofera. |
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| Journal |
J Biol Chem 238:1737-1742 (1963) |
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| Reference |
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| Authors |
SHIIO I, SHIIO T, MCFADDEN BA. |
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| Title |
ISOCITRATE LYASE FROM PSEUDOMONAS INDIGOFERA. I. PREPARATION, AMINO ACID COMPOSITION AND MOLECULAR WEIGHT. |
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| Journal |
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| Reference |
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| Authors |
VICKERY HB. |
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| Title |
A suggested new nomenclature for the isomers of isocitric acid. |
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| Journal |
J Biol Chem 237:1739-41 (1962) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.3.1 |
| ExPASy - ENZYME nomenclature database: | 4.1.3.1 |
| BRENDA, the Enzyme Database: | 4.1.3.1 |
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