Entry |
|
Name |
isocitrate lyase;
isocitrase;
isocitritase;
isocitratase;
threo-Ds-isocitrate glyoxylate-lyase;
isocitrate glyoxylate-lyase
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Class |
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
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Sysname |
isocitrate glyoxylate-lyase (succinate-forming)
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Reaction(IUBMB) |
isocitrate = succinate + glyoxylate [RN: R00479]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate [3].
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History |
EC 4.1.3.1 created 1961
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Pathway |
ec00630 | Glyoxylate and dicarboxylate metabolism |
ec01110 | Biosynthesis of secondary metabolites |
ec01120 | Microbial metabolism in diverse environments |
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Orthology |
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Genes |
» show all
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Reference |
1 |
Authors |
McFadden, B.A. and Howes, W.V. |
Title |
Crystallisation and some properties of isocitrate lyase from Pseudomonas indigofera. |
Journal |
J Biol Chem 238:1737-1742 (1963) |
Reference |
|
Authors |
SHIIO I, SHIIO T, MCFADDEN BA. |
Title |
ISOCITRATE LYASE FROM PSEUDOMONAS INDIGOFERA. I. PREPARATION, AMINO ACID COMPOSITION AND MOLECULAR WEIGHT. |
Journal |
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Reference |
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Authors |
VICKERY HB. |
Title |
A suggested new nomenclature for the isomers of isocitric acid. |
Journal |
J Biol Chem 237:1739-41 (1962) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.3.1 |
ExPASy - ENZYME nomenclature database: | 4.1.3.1 |
BRENDA, the Enzyme Database: | 4.1.3.1 |
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