Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
BRITE hierarchy

chorismate pyruvate-lyase (amino-accepting; anthranilate-forming)

chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate [RN:R00986]

R00986;
(other) R00985
Reaction

chorismate [CPD:C00251];
L-glutamine [CPD:C00064]

In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase ), EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.2.1.20 (tryptophan synthase) and EC 5.3.1.24 (phosphoribosylanthranilate isomerase)]. The native enzyme in the complex uses either glutamine or, less efficiently, NH3. The enzyme separated from the complex uses NH3 only.

EC 4.1.3.27 created 1972