KEGG   ENZYME: 4.2.1.156
Entry
EC 4.2.1.156                Enzyme                                 

Name
L-talarate dehydratase;
L-talarate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
L-altarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)
Reaction(IUBMB)
L-altarate = 5-dehydro-4-deoxy-D-glucarate + H2O [RN:R11075]
Reaction(KEGG)
R11075
Substrate
L-altarate [CPD:C21088]
Product
5-dehydro-4-deoxy-D-glucarate [CPD:C00679];
H2O [CPD:C00001]
Comment
Requires Mg2+. The enzyme, isolated from the bacteria Salmonella typhimurium and Polaromonas sp. JS666, also has activity with galactarate (cf. EC 4.2.1.42, galactarate dehydratase).
History
EC 4.2.1.156 created 2015
Orthology
K20023  L-talarate/galactarate dehydratase
Genes
EFE: EFER_1473
STY: STY4099
STT: t3822
SEX: STBHUCCB_40340
SENT: TY21A_19420
STM: STM3697
SEO: STM14_4457
SEV: STMMW_36851
SEY: SL1344_3662
SEM: STMDT12_C37540
SENI: CY43_19185
SPT: SPA3549
SEK: SSPA3312
SEC: SCH_3621(yin)
SHB: SU5_04174
SENS: Q786_18075
SED: SeD_A4083
SEG: SG3734
SEL: SPUL_3867
SET: SEN3519
SENA: AU38_17975
SENO: AU37_18165
SENV: AU39_18170
SENQ: AU40_20245
SENL: IY59_18610
SEEP: I137_18555
SENE: IA1_17970
KVA: Kvar_2413
KPE: KPK_2460
KOX: KOX_19905
KOE: A225_2851
CRO: ROD_42111
CAMA: F384_07290
RTG: NCTC13098_03845(rhmD_2)
ECA: ECA0998
PATR: EV46_05095
PATO: GZ59_10330(lfeW)
PCT: PC1_0918
PEC: W5S_3388
SOD: Sant_2144
DDD: Dda3937_02647(lfeW)
DDQ: DDI_0313
PAM: PANA_1262(mdlA)
PLF: PANA5342_3023(mdlA1)
PAJ: PAJ_0583(mdlA)
PMK: MDS_1245
PSTT: CH92_11115
PSES: PSCI_1981
PALL: UYA_05665
CGD: CR3_3082
BCT: GEM_3437
BGO: BM43_2754
PLG: NCTC10937_00398(mdlA_1)
CABA: SBC2_17980
ODI: ODI_R0434
POL: Bpro_0435
DAC: Daci_4290
LIH: L63ED372_02032(mdlA_1)
RLE: pRL120237
RLG: Rleg_5348
MET: M446_3263
MNO: Mnod_4686
CAMG: CAMM_01125
RHB: NY08_3282
SBH: SBI_09219
SHY: SHJG_0937
SMAL: SMALA_0245
ART: Arth_0032
ARR: ARUE_c00340(mdlA1)
AAU: AAur_0037(clcB)
ACH: Achl_0038
IDO: I598_2363(mdlA)
PAUS: NCTC13651_01417(mdlA_1)
MPH: MLP_05990
NDA: Ndas_1050
GOB: Gobs_2394
BSD: BLASA_1681(mdlA)
SEN: SACE_4598
AMYY: YIM_26245(mdlA2)
AMI: Amir_4042
ACTI: UA75_05550
ACAD: UA74_05545
 » show all
Reference
1  [PMID:17649980]
  Authors
Yew WS, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA
  Title
Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
  Journal
Biochemistry 46:9564-77 (2007)
DOI:10.1021/bi7008882
  Sequence
[stm:STM3697]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.156
IUBMB Enzyme Nomenclature: 4.2.1.156
ExPASy - ENZYME nomenclature database: 4.2.1.156
BRENDA, the Enzyme Database: 4.2.1.156

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