KEGG   ENZYME: 4.2.1.169
Entry
EC 4.2.1.169                Enzyme                                 

Name
3-vinyl bacteriochlorophyllide d 31-hydratase;
bchV (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
3-vinylbacteriochlorophyllide-d 31-hydro-lyase
Reaction(IUBMB)
a 3-(1-hydroxyethyl) bacteriochlorophyllide d = a 3-vinyl bacteriochlorophyllide d + H2O [RN:R11506]
Reaction(KEGG)
Substrate
3-(1-hydroxyethyl) bacteriochlorophyllide d
Product
3-vinyl bacteriochlorophyllide d [CPD:C21426];
H2O [CPD:C00001]
Comment
This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green flimentous bacteria (Chloroflexaceae), is involved in the biosynthesis of bacteriochlorophylls c, d and e. It acts in the direction of hydration, and the hydroxyl group that is formed is essential for the ability of the resulting bacteriochlorophylls to self-aggregate in the chlorosomes, unique light-harvesting antenna structures found in these organisms. The product is formed preferentially in the (R)-configuration.
History
EC 4.2.1.169 created 2016
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K13603  3-vinyl bacteriochlorophyllide hydratase
Genes
CTE: CT1776
CPC: Cpar_0430
CLZ: BIU88_02085 BIU88_11020
CCH: Cag_1644
CPH: Cpha266_0198 Cpha266_2005
CPB: Cphamn1_0268
CLI: Clim_1974
PVI: Cvib_0370
PLT: Plut_0408
PPH: Ppha_2338 Ppha_2749
PAA: Paes_1805
PROS: CHL67_01210(bchF)
CTS: Ctha_2718
 » show all
Reference
1  [PMID:16245042]
  Authors
Frigaard NU, Chew AG, Li H, Maresca JA, Bryant DA
  Title
Chlorobium tepidum: insights into the structure, physiology, and metabolism of a green sulfur bacterium derived from the complete genome sequence.
  Journal
Photosynth Res 78:93-117 (2003)
DOI:10.1023/B:PRES.0000004310.96189.b4
  Sequence
[cte:CT1776]
Reference
2  [PMID:26331578]
  Authors
Harada J, Teramura M, Mizoguchi T, Tsukatani Y, Yamamoto K, Tamiaki H
  Title
Stereochemical conversion of C3-vinyl group to 1-hydroxyethyl group in bacteriochlorophyll c by the hydratases BchF and BchV: adaptation of green sulfur bacteria to limited-light environments.
  Journal
Mol Microbiol 98:1184-98 (2015)
DOI:10.1111/mmi.13208
  Sequence
[cte:CT1776]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.169
IUBMB Enzyme Nomenclature: 4.2.1.169
ExPASy - ENZYME nomenclature database: 4.2.1.169
BRENDA, the Enzyme Database: 4.2.1.169

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