KEGG   ENZYME: 4.2.1.171
Entry
EC 4.2.1.171                Enzyme                                 

Name
cis-L-3-hydroxyproline dehydratase;
cis-L-3-hydroxyproline hydro-lyase;
c3LHypD
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
cis-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming)
Reaction(IUBMB)
cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O [RN:R11625]
Reaction(KEGG)
R11625
Substrate
cis-3-hydroxy-L-proline [CPD:C19706]
Product
1-pyrroline-2-carboxylate [CPD:C03564];
H2O [CPD:C00001]
History
EC 4.2.1.171 created 2017
Pathway
ec00330  Arginine and proline metabolism
Orthology
K09123  cis-L-3-hydroxyproline dehydratase
K21624  cis-L-3-hydroxyproline dehydratase
Genes
LAK: 106158194
FGR: FGSG_12672
FPU: FPSE_04942
FVR: FVEG_06026
FOX: FOXG_08647
NHE: NECHADRAFT_47437 NECHADRAFT_75968
TRE: TRIREDRAFT_59073
TRR: M419DRAFT_74960
PLJ: VFPFJ_04120
CFJ: CFIO01_08286
ANI: AN8629.2
ANG: ANI_1_578044(An05g02230)
SMIN: v1.2.027818.t1(symbB.v1.2.027818.t1)
PAE: PA1259
PAEV: N297_1298
PAEI: N296_1298
PAEP: PA1S_19620
PAEM: U769_19460
PAEL: T223_20710
PAEU: BN889_01338(acnD)
PAEG: AI22_14345
PAEC: M802_1295
PAEO: M801_1298
PFE: PSF113_3724(acnD)
PSTT: CH92_01045
ABX: ABK1_2717
ABH: M3Q_2866
MBS: MRBBS_3090(tfdDII) MRBBS_3771
HAM: HALO1339
PLG: NCTC10937_03090(acnD_2)
DALK: DSCA_32400
MHUA: MCHK_0861
AMIH: CO731_04096(ykfB)
SME: SM_b20269
SMER: DU99_32025
SMD: Smed_3862
ATU: Atu4683
RLE: pRL120183
RLG: Rleg_2143
RHT: NT26_0740
SHZ: shn_20870
SNO: Snov_0156
RUT: FIU92_00705(hpbD1) FIU92_00710(hpbD2) FIU92_00715(hpbD3) FIU92_20915(hpbD5)
PDE: Pden_4854
LAQU: R2C4_00195
LABT: FIU93_09480(hpbD2)
ROH: FIU89_04720(hpbD)
ROP: ROP_33630
MPH: MLP_31270
PSL: Psta_4279
PIR: VN12_04975(hpbD)
RUL: UC8_12350(hpbD)
PLM: Plim_2539
PEH: Spb1_33100(hpbD)
FMR: Fuma_04875(ykfB_3)
BVO: Pan97_28130(hpbD)
GES: VT84_28150(hpbD)
AGV: OJF2_01180(hpbD)
GBA: J421_4704
 » show all
Reference
1  [PMID:25608448]
  Authors
Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA
  Title
A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily.
  Journal
J Am Chem Soc 137:1388-91 (2015)
DOI:10.1021/ja5103986
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.171
IUBMB Enzyme Nomenclature: 4.2.1.171
ExPASy - ENZYME nomenclature database: 4.2.1.171
BRENDA, the Enzyme Database: 4.2.1.171

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