KEGG   ENZYME: 4.2.1.43
Entry
EC 4.2.1.43                 Enzyme                                 

Name
2-dehydro-3-deoxy-L-arabinonate dehydratase;
2-keto-3-deoxy-L-arabinonate dehydratase;
2-dehydro-3-deoxy-L-arabinonate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
Reaction(IUBMB)
2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O [RN:R02278]
Reaction(KEGG)
R02278
Substrate
2-dehydro-3-deoxy-L-arabinonate [CPD:C00684]
Product
2,5-dioxopentanoate [CPD:C00433];
H2O [CPD:C00001]
History
EC 4.2.1.43 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K13876  2-keto-3-deoxy-L-arabinonate dehydratase
Genes
CTU: CTU_06570
KMI: VW41_03260
CAF: AL524_22380
EBT: EBL_c33280
KCO: BWI95_18060
BUF: D8682_18995
BAGE: BADSM9389_06400
SPE: Spro_0707
SLQ: M495_02890
SQU: E4343_13080
SOD: Sant_0675
RPI: Rpic_3006
REH: H16_B0213(dapA2)
CNC: CNE_2c01980(dapA1)
CGD: CR3_3974(araD)
BTQ: BTQ_4919(araD)
BTJ: BTJ_3543(araD)
BTZ: BTL_4392(araD)
BTD: BTI_5591(araD)
BTV: BTHA_3565(araD)
BTHE: BTN_4043(araD)
BTHM: BTRA_4050(araD)
BTHA: DR62_4079
BTHL: BG87_4375(AraD)
BVE: AK36_4877(araD)
BCEN: DM39_5046(araD) DM39_6177(araD)
BCEW: DM40_3367(araD)
BCEO: I35_6679
BMJ: BMULJ_05321(dapA)
BMU: Bmul_3204
BMK: DM80_4584(araD)
BMUL: NP80_3349(araD)
BCED: DM42_5188(araD)
BDL: AK34_5007(araD)
BUB: BW23_3987(araD) BW23_4351(araD)
BLAT: WK25_29415
BTEI: WS51_10640
BGU: KS03_2640(araD)
BGO: BM43_5015(araD)
BUK: MYA_3489
BUL: BW21_5279(araD)
BPH: Bphy_6711
CABA: SBC2_14340(dapA_3) SBC2_66650(araD)
BHO: D560_1639
BHM: D558_1627
AXX: ERS451415_04605(yagE_2)
ODI: ODI_R4258
RFR: Rfer_0453
POL: Bpro_2837
AAV: Aave_2247
DAC: Daci_4983
CTES: O987_23535
HPSE: HPF_09020(araD)
HSE: Hsero_1368(dapA)
HRB: Hrubri_1189(dapA)
URU: DSM104443_00662(araD_1)
MES: Meso_3971
AMIH: CO731_04159(yagE_2)
SMER: DU99_23820
EAD: OV14_a1105(dapA)
SHZ: shn_14790
BJA: bll7953(bll7953)
BRA: BRADO1813
BBT: BBta_2133
BRS: S23_65840
AOL: S58_57230
BRAD: BF49_3436
BRO: BRAD285_5472(araD)
BVZ: BRAD3257_8478(araD)
XAU: Xaut_1021
SNO: Snov_0118
MOR: MOC_5613
MAQU: Maq22A_c05765(dapA)
BID: Bind_3080
HDI: HDIA_0216(araD)
LABT: FIU93_14080(araD1) FIU93_16605(araD2)
SIL: SPOA0244
PDE: Pden_4666
DSH: Dshi_2446
RHC: RGUI_3959
RID: RIdsm_01841(araD)
LVS: LOKVESSMR4R_03077(araD)
MALU: KU6B_19310
PALW: PSAL_020910(araD)
SPHI: TS85_03755
ACR: Acry_2738
AZL: AZL_e03630(dapA)
ALI: AZOLI_p50377(araD)
SRN: A4G23_03540(dapA_3)
MOY: CVS54_01202(araD)
BCV: Bcav_3940
AMYY: YIM_17550(araD)
PAUT: Pdca_64040
ACTI: UA75_20040
ACAD: UA74_19550
RUL: UC8_01250(araD)
ROL: CA51_31580(dapA_3)
LCRE: Pla8534_61970(araD)
AAGG: ETAA8_26400(araD)
PLS: VT03_23390(dapA_3)
FMR: Fuma_05619(araD)
GMR: GmarT_22610(araD)
GPN: Pan110_21890(araD)
SDYN: Mal52_40300(araD_1) Mal52_45600(araD_2)
PLON: Pla110_17110(araD_1) Pla110_46420(araD_2)
ABAC: LuPra_02639(araD_1)
SLI: Slin_0609
 » show all
Reference
1  [PMID:5954356]
  Authors
Stoolmiller AC, Abeles RH.
  Title
Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila.
  Journal
J Biol Chem 241:5764-71 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.43
IUBMB Enzyme Nomenclature: 4.2.1.43
ExPASy - ENZYME nomenclature database: 4.2.1.43
BRENDA, the Enzyme Database: 4.2.1.43
CAS: 37263-10-8

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