KEGG   ENZYME: 4.2.1.48Help
Entry
EC 4.2.1.48                 Enzyme                                 

Name
D-glutamate cyclase;
D-glutamate hydro-lyase (cyclizing)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)
Reaction(IUBMB)
D-glutamate = 5-oxo-D-proline + H2O [RN:R01583]
Reaction(KEGG)
Substrate
D-glutamate [CPD:C00217]
Product
5-oxo-D-proline [CPD:C02237];
H2O [CPD:C00001]
Comment
Also acts on various derivatives of D-glutamate.
History
EC 4.2.1.48 created 1972
Pathway
ec00471  D-Glutamine and D-glutamate metabolism
ec01100  Metabolic pathways
Orthology
K22210  D-glutamate cyclase
Genes
HSA: 80017(DGLUCY)
PTR: 453104(DGLUCY)
PPS: 100971567(C14H14orf159)
GGO: 101153207(DGLUCY)
PON: 100172319(DGLUCY)
NLE: 100586901(DGLUCY)
MCC: 700168(DGLUCY)
MCF: 102135732(C7H14orf159)
CSAB: 103229551(C24H14orf159)
RRO: 104656701(DGLUCY)
RBB: 108523309(CUNH14orf159)
SBQ: 101047007
MMU: 217830(Dglucy)
MCAL: 110306840(C12H14orf159)
MPAH: 110324645(C7H14orf159)
RNO: 362769(RGD1311756)
MUN: 110558364(CUNH14orf159)
CGE: 100753550(Dglucy)
NGI: 103724611(CUNH14orf159)
HGL: 101711224
CCAN: 109699498(CUNH14orf159)
TUP: 102469364
CFA: 100688910(DGLUCY)
VVP: 112907347(DGLUCY)
AML: 100482436(CUNH14orf159)
UMR: 103670181
UAH: 113267360(DGLUCY)
ORO: 101371157
ELK: 111148542
PTG: 102949759
PPAD: 109274456(CUNH14orf159)
AJU: 106987920(DGLUCY)
SSC: 100626547(C7H14orf159)
CFR: 102521322(DGLUCY)
CDK: 105095965(DGLUCY)
BACU: 102999377
LVE: 103084864
OOR: 101287758
DLE: 111175940(DGLUCY)
ECB: 100063012(DGLUCY)
EPZ: 103558013
EAI: 106825335
MYB: 102252495
MYD: 102753826
MNA: 107531588
HAI: 109382680(CUNH14orf159)
DRO: 112311934(DGLUCY)
PALE: 102898067(DGLUCY)
RAY: 107515436
MJV: 108399442(CUNH14orf159)
LAV: 100659904(DGLUCY)
MDO: 100017774(C1H14orf159)
SHR: 100931620(DGLUCY)
PCW: 110217799(CUNH14orf159)
OAA: 100083826(DGLUCY)
GGA: 423409(C5H14orf159)
MGP: 100539918(DGLUCY)
CJO: 107315200(DGLUCY)
NMEL: 110402184(C6H14orf159)
APLA: 101791243(DGLUCY)
ACYG: 106036649
TGU: 100229540(DGLUCY)
LSR: 110471379(DGLUCY)
SCAN: 103826477(DGLUCY)
GFR: 102037421
FAB: 101806679(C5H14orf159)
PHI: 102108442
PMAJ: 107205561(C5H14orf159)
CCAE: 111929884(DGLUCY)
CCW: 104685987(CUNH14orf159)
ETL: 114058212(DGLUCY)
FPG: 101913280
FCH: 102058374(DGLUCY)
CLV: 102096431(CUNH14orf159)
EGZ: 104135348
NNI: 104022218
ACUN: 113480812(DGLUCY)
PADL: 103912999
AAM: 106482923
ASN: 102380281(DGLUCY)
AMJ: 102576478(CUNH14orf159)
PSS: 102453950(DGLUCY)
CMY: 102931212
CPIC: 101937326
ACS: 100562196(c1h14orf159)
PVT: 110086580(CUNH14orf159)
PBI: 103063698(DGLUCY)
PMUR: 107297288(DGLUCY)
TSR: 106546543
PMUA: 114591021(DGLUCY)
GJA: 107113340
XLA: 108698713(c14orf159.L)
XTR: 549215(dglucy)
NPR: 108788696(CUNH14orf159)
DRE: 560387(c17h14orf159)
SRX: 107730207
SANH: 107679776
SGH: 107582942
CCAR: 109107902(c34h14orf159)
AMEX: 103041880(dglucy)
EEE: 113574126(dglucy)
TRU: 101064729(dglucy)
MZE: 101472904(dglucy)
ONL: 100699337(dglucy)
OLA: 101156702(dglucy)
XMA: 102226444(dglucy)
XCO: 114134371(dglucy)
PRET: 103460669
CVG: 107101552
NFU: 107391670(csgr16h14orf159)
KMR: 108247027(dglucy)
ALIM: 106521235
POV: 109628237(cunh14orf159)
BPEC: 110163870 110166339(cunh14orf159)
MALB: 109965009(cunh14orf159)
SASA: 106611165(cssa09h14orf159)
OTW: 112256792(dglucy)
SALP: 111963420(dglucy)
ELS: 105015466(dglucy)
SFM: 108933257(dglucy)
PKI: 111852007(dglucy)
LCM: 102346195
CMK: 103189663
RTP: 109913902(cunh14orf159)
SPU: 577417
SKO: 100368287
ADF: 107345094
DGT: 114520257
HMG: 100204445
AQU: 100637788
SMIN: v1.2.019446.t1(symbB.v1.2.019446.t1) v1.2.019446.t2(symbB.v1.2.019446.t2)
SPAR: SPRG_00060
SMER: DU99_19640
CID: P73_2835
RSU: NHU_04230
LPIL: LIP_2227
BLA: BLA_0133
BBB: BIF_01419
BBC: BLC1_0133
BLV: BalV_0138
BLW: W7Y_0140
BLS: W91_0141
BANI: Bl12_0130
BANL: BLAC_00730
BANM: EN10_00730
BDE: BDP_0108
BDN: BBDE_0098
BTP: D805_1222
BARC: AOA65_1114
 » show all
Taxonomy
Reference
1  [PMID:14087295]
  Authors
MEISTER A, BUKENBERGER MW, STRASSBURGER M.
  Title
THE OPTICALLY-SPECIFIC  ENZYMATIC CYCLIZATION OF D-GLUTAMATE.
  Journal
Biochem Z 338:217-29 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.48
IUBMB Enzyme Nomenclature: 4.2.1.48
ExPASy - ENZYME nomenclature database: 4.2.1.48
BRENDA, the Enzyme Database: 4.2.1.48
CAS: 37290-80-5

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