Entry
Name
3-hydroxybutyryl-CoA dehydratase;
D-3-hydroxybutyryl coenzyme A dehydratase;
D-3-hydroxybutyryl-CoA dehydratase;
enoyl coenzyme A hydrase (D);
(3R)-3-hydroxybutanoyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)
Reaction(IUBMB)
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O [RN:
R03027 ]
Reaction(KEGG)
Substrate
(3R)-3-hydroxybutanoyl-CoA [CPD:
C03561 ]
Product
Comment
Also acts on crotonoyl thioesters of pantetheine and acyl-carrier protein.
History
EC 4.2.1.55 created 1972
Pathway
ec00630 Glyoxylate and dicarboxylate metabolism
ec01120 Microbial metabolism in diverse environments
Orthology
K17865 3-hydroxybutyryl-CoA dehydratase
Genes
KPSE : IP581_10455 IP581_17690
VPF : M634_03020 M634_03165
PAEB : NCGM1900_2978(phaJ1)
PPB : PPUBIRD1_1345(phaJ1)
PMOS : O165_002325 O165_002680
PPRC : PFLCHA0_c27420(maoC1) PFLCHA0_c46750(phaJ)
PFO : Pfl01_4044 Pfl01_4356
PMUD : NCTC8068_04011(phaJ_2)
PTOL : I7845_21090 I7845_22655
PFZ : AV641_11730 AV641_17410
PTAE : NCTC10697_03354(phaJ)
PSNC : C0058_05460 C0058_25055
PALL : UYA_07825 UYA_22875 UYA_22895
AVL : AvCA_30160(phaJ) AvCA_46430
AVD : AvCA6_30160(phaJ) AvCA6_46430
MARA : D0851_02820 D0851_17975
MARJ : MARI_12670(phaJ_1) MARI_25330(phaJ_2)
MSHE : MAALD49_04020 MAALD49_18690
MMEE : NLK58_03300 NLK58_18850
PLZ : S4054249_13830 S4054249_25125
CYQ : Q91_1188 Q91_1189 Q91_1228 Q91_1346(maoC)
CZA : CYCME_1122 CYCME_1200 CYCME_1238 CYCME_1239
CYY : CPC19_06090 CPC19_06465 CPC19_06660 CPC19_06665
SEDS : AAY24_02455 AAY24_13240
MPRF : J8N69_05350 J8N69_15915
MSEC : LN244_06510 LN244_10085 LN244_12405
NCU : F0U83_08575 F0U83_16305
NJP : NEJAP_0761 NEJAP_1792 NEJAP_3517
AJP : AMJAP_0228 AMJAP_1906
EMP : EZMO1_2317(phaJ1) EZMO1_3571(phaJ2)
CFON : HZU75_02510 HZU75_12510
REU : Reut_C6351 Reut_C6428
CUU : BKK79_00400 BKK79_14450
BGP : BGL_1c19610 BGL_2c01630
BPLA : bpln_1g17920 bpln_2g01610
BGE : BC1002_3440 BC1002_5759 BC1002_5762
BUZ : AYM40_05770 AYM40_05775
BCAI : K788_0003005 K788_0006983
PHS : C2L64_24150 C2L64_42385
PTER : C2L65_23925 C2L65_42390
PEW : KZJ38_27760 KZJ38_28450
PSAA : QEN71_14010 QEN71_18705 QEN71_30585 QEN71_35790
PKF : RW095_05140 RW095_05155 RW095_22760
PLG : NCTC10937_04160(phaJ)
BPER : BN118_1971 BN118_3115
BBM : BN115_1094 BN115_2969
BHZ : ACR54_01126(phaJ_1) ACR54_01127
BBRO : BAU06_01355 BAU06_01360
BFZ : BAU07_01265 BAU07_01270
AXY : AXYL_06652 AXYL_06653
PIG : EGT29_28220 EGT29_28225
DAER : H9K75_11435 H9K75_11440
ARES : IWH25_01775 IWH25_13365
ABRE : pbN1_28640 pbN1_28770
THAG : CKCBHOJB_02697(phaJ)
FPHO : SHINM1_005250 SHINM1_022190
RIR : BN877_p0414(maoC) BN877_p0428
ROY : G3A56_21005 G3A56_21010
HOE : IMCC20628_00103 IMCC20628_00104
BARH : WN72_19570 WN72_19575
BVZ : BRAD3257_2223 BRAD3257_5053 BRAD3257_5054
BCOU : IC761_23010 IC761_31935
VGO : GJW-30_1_01981(phaJ)
XDI : EZH22_09630 EZH22_21710
MAQU : Maq22A_c17200(croR)
HMC : HYPMC_3849 HYPMC_4041
BVR : BVIR_1112 BVIR_2606 BVIR_2707
BLAG : BLTE_01590 BLTE_14070
RBM : TEF_02600 TEF_02605 TEF_16395
LAP : ACP90_05605 ACP90_23150
LABR : CHH27_15035 CHH27_25440
LABT : FIU93_00895(phaJ1) FIU93_11245(phaJ3)
LAGG : B0E33_06575 B0E33_17160
PSTG : E8M01_07705 E8M01_17000
CCS : CCNA_00741 CCNA_03613
CHQ : AQ619_02705 AQ619_03860
CAUF : CSW63_02530 CSW63_19775
BVY : NCTC9239_00561(phaJ)
BREU : FKQ52_02985 FKQ52_04580
TSV : DSM104635_01280(phaJ)
RLI : RLO149_c027240 RLO149_c040990
CON : TQ29_03075 TQ29_17495
YAN : AYJ57_19300 AYJ57_19880 AYJ57_19885
SINL : DSM14862_00676(phaJ)
SPSE : SULPSESMR1_02408(phaJ)
RMM : ROSMUCSMR3_00429(phaJ)
RID : RIdsm_04192(phaJ_2) RIdsm_05597
AHT : ANTHELSMS3_02031(phaJ) ANTHELSMS3_05137
SAGU : CDO87_04895 CDO87_26440
RSU : NHU_00311 NHU_03705 NHU_03706
RHM : B5V46_02940 B5V46_16995 B5V46_17000
LVS : LOKVESSMR4R_00151(phaJ)
PGV : SL003B_3440 SL003B_3444
RGI : RGI145_20615 RGI145_20620
ABS : AZOBR_70019 AZOBR_p310108
ABQ : ABAZ39_10485 ABAZ39_28990
ABF : AMK58_10940 AMK58_15735
ATI : AL072_01255 AL072_21580
AZT : TSH58p_01350 TSH58p_08135
AOZ : HUE56_20650 HUE56_26220
NCB : C0V82_02155 C0V82_24630
FER : FNB15_00380 FNB15_09820
HADH : FRZ61_01170(maoC) FRZ61_07030
VSU : P3M64_05570 P3M64_10690
HBI : HBZC1_10240 HBZC1_13270
HET : BBW65_00060 BBW65_07675
DWD : DSCW_26670(maoC) DSCW_55620
DALK : DSCA_24280 DSCA_36530(maoC) DSCA_38200(phaJ)
DML : Dmul_05700 Dmul_35980(maoC)
DLI : dnl_06140 dnl_32660 dnl_35850 dnl_62050
DEK : DSLASN_04820(phaJ) DSLASN_41670
DTI : Desti_4582 Desti_5416
BAH : BAMEG_2661 BAMEG_3270
BAX : H9401_1240 H9401_1827
BANT : A16_13690 A16_19670
BANR : A16R_13890 A16R_19900
BANS : BAPAT_1244 BAPAT_1843
BANH : HYU01_06745 HYU01_09675
BCZ : BCE33L1205(crt) BCE33L1747
BCU : BCAH820_1401 BCAH820_1965
BTC : CT43_CH1243 CT43_CH3193
BTF : YBT020_07210 YBT020_10015
BTG : BTB_c13560(phaJ) BTB_c33270
BTHT : H175_ch1257 H175_ch3248
BTHU : YBT1518_07575 YBT1518_17740
BWE : BcerKBAB4_1227 BcerKBAB4_2984
BWW : bwei_1796 bwei_3696(phaJ)
BMYO : BG05_2820 BG05_4056 BG05_4586
BTY : Btoyo_0490 Btoyo_3952
BWD : CT694_07050 CT694_17180
BTRO : FJR70_02975 FJR70_09950 FJR70_28835
BMOB : MLA2C4_06970 MLA2C4_09795 MLA2C4_17100
BNT : GSN03_06655 GSN03_15445
BALU : QRY64_08990 QRY64_11770
BFD : NCTC4823_01373(phaJ_1) NCTC4823_02207(phaJ_2)
BACO : OXB_2246 OXB_2612 OXB_2769 OXB_3265
BARD : QRY57_08340 QRY57_16455
BCOH : BC6307_06140 BC6307_16805
CFIR : NAF01_03485 NAF01_19920
BDA : FSZ17_03825 FSZ17_17425 FSZ17_20835
GTE : GTCCBUS3UF5_23980 GTCCBUS3UF5_30780
GTK : GT3570_10060 GT3570_13400
GTM : GT3921_05765 GT3921_08980
GLI : GLN3_03490 GLN3_06495
BCAL : CWI35_14535 CWI35_17870
GYC : GYMC61_0784 GYMC61_2956
GYA : GYMC52_2083 GYMC52_2768
GCT : GC56T3_0760 GC56T3_1395
GGH : GHH_c22030 GHH_c28140
GJF : M493_04540 M493_10820 M493_14175
GEA : GARCT_02078(paaZ) GARCT_02788(phaJ)
GSE : GT50_05155 GT50_16730
GSR : GS3922_02550 GS3922_06295
GEJ : A0V43_08510 A0V43_11600
GZA : IC807_04635 IC807_06700 IC807_09880
ACAI : ISX45_05340 ISX45_11950
LFU : HR49_06420 HR49_12285
LIU : OU989_16385 OU989_22705
VIL : CFK37_12970 CFK37_18295
VNE : CFK40_08355 CFK40_15835
VPN : A21D_00474 A21D_02972(phaJ)
FAR : ABE41_006390 ABE41_014290
SJE : AAV35_004695 AAV35_013940
PBUT : DTO10_22600 DTO10_24050 DTO10_24065
PASA : BAOM_1364 BAOM_2688 BAOM_2692 BAOM_4348
PPSR : I6J18_04630 I6J18_04650 I6J18_18595
PERI : RE409_10995 RE409_12305 RE409_12320
PSYO : PB01_00950 PB01_13015
NMK : CHR53_02825 CHR53_21220
MSEM : GMB29_11890 GMB29_20845
AIA : AWH56_014315 AWH56_019445
BLEN : NCTC4824_01401(phaJ)
BVJ : I5776_02905 I5776_06970
BOU : I5818_08265 I5818_19470
BLR : BRLA_c026570 BRLA_c036240
BRW : GOP56_05805 GOP56_10200
PGQ : FK545_14955 FK545_17035
PLIQ : QWY22_07350 QWY22_09620
PSHE : QWY16_07275 QWY16_09850
KUR : ASO14_2938 ASO14_892
KZO : NCTC404_02038(phaJ_1) NCTC404_02837(phaJ_2)
SPSY : AZE41_07730 AZE41_11215
SPAE : E2C16_02790 E2C16_15565
VIJ : JNUCC6_03255 JNUCC6_09660
ECEC : NCTC12421_01170(phaJ)
VCP : H9L18_06295 H9L18_08780
VHY : G7082_11880 G7082_14615
CBE : Cbei_2038 Cbei_3349 Cbei_4279
CBZ : Cbs_2038 Cbs_3349 Cbs_4279
CBEI : LF65_02210 LF65_03834
CSR : Cspa_c20870 Cspa_c50200
CEU : A7L45_02280 A7L45_02305
CDRK : B9W14_06510 B9W14_16390
CDY : F3K33_10125 F3K33_17010
CCAA : KQH81_02190 KQH81_12630
CINT : HZF06_12405 HZF06_22530
CRS : FQB35_01410 FQB35_11710
FPLA : A4U99_15190 A4U99_15635 A4U99_17360
SWO : Swol_1242 Swol_1355 Swol_1356
DMT : DESME_03295 DESME_03310
DKU : Desku_0341 Desku_2927
TFR : BR63_00145 BR63_02840 BR63_07200 BR63_10695
IBU : IB211_00153c IB211_00613 IB211_01395c IB211_02541
ARF : AR1Y2_1561 AR1Y2_2849 AR1Y2_3145
ACAC : EYQ97_02075 EYQ97_04060 EYQ97_09760
PHAR : NCTC13077_00525(phaJ)
MEG : DKB62_02810 DKB62_04045 DKB62_04060 DKB62_07640
MANA : MAMMFC1_02836(phaJ)
STED : SPTER_29440(phaJ_1) SPTER_47280(phaJ_2)
TBM : BK010_00725 BK010_05255
TBZ : BK011_00625 BK011_05225
ACIT : HPK19_08915 HPK19_10730
PSUL : AU252_00650 AU252_00680
BSOL : FSW04_11295 FSW04_11415
GES : VT84_09910(paaZ_1) VT84_34445(paaZ_2)
GMS : SOIL9_19400 SOIL9_63990
LKB : LPTSP3_g10640(maoC_1)
FVA : FV113G1_17260 FV113G1_26850
FUL : C4N20_10240 C4N20_13620
FNF : BSQ88_04040 BSQ88_06305
IPO : Ilyop_0277 Ilyop_2111
CJG : NCTC13459_01817(phaJ)
CANT : NCTC13489_01890(phaJ)
HALJ : G9465_03195 G9465_21230 G9465_22435
HALI : BV210_04405 BV210_08280
HBO : Hbor_14770 Hbor_29980
HLM : DV707_16735 DV707_16740
HSAL : JMJ58_03555 JMJ58_16550
NPE : Natpe_1217 Natpe_2715
NVR : FEJ81_06610 FEJ81_12550
NPL : FGF80_04760 FGF80_12190
HALY : HYG82_00975 HYG82_07110
HJT : DVR14_03545 DVR14_15280
HLO : J0X27_01860 J0X27_02395
NGE : Natgr_0367 Natgr_0541
NOU : Natoc_1091 Natoc_1375 Natoc_2976
HLC : CHINAEXTREME12565 CHINAEXTREME18540
NAJ : B1756_01230 B1756_01895
NBG : DV706_11615 DV706_12155
NAS : GCU68_00520 GCU68_10990
SIS : LS215_0793 LS215_1174
SIA : M1425_0814 M1425_1078
SIY : YG5714_0819 YG5714_1067
SIN : YN1551_1789 YN1551_2032
SULA : BFU36_00745 BFU36_12660
PSYT : DSAG12_00082 DSAG12_00785 DSAG12_01221
» show all
Taxonomy
Reference
Authors
Moskowitz GJ, Merrick JM.
Title
Metabolism of poly-beta-hydroxybutyrate. II. Enzymatic synthesis of D-(-)-beta hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.55
ExPASy - ENZYME nomenclature database: 4.2.1.55