KEGG   ENZYME: 4.2.1.56
Entry
EC 4.2.1.56                 Enzyme                                 

Name
itaconyl-CoA hydratase;
itaconyl coenzyme A hydratase;
citramalyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Reaction(IUBMB)
citramalyl-CoA = itaconyl-CoA + H2O [RN:R02490]
Reaction(KEGG)
R02490 > R02491
Substrate
citramalyl-CoA [CPD:C00904]
Product
itaconyl-CoA [CPD:C00531];
H2O [CPD:C00001]
History
EC 4.2.1.56 created 1972
Pathway
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
Orthology
K18290  itaconyl-CoA hydratase
K18291  itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase
Genes
STM: STM3119
SEO: STM14_3768
SEV: STMMW_30791
SEY: SL1344_3093
SEM: STMDT12_C31720
SEJ: STMUK_3107
SEB: STM474_3268
SEF: UMN798_3389
SETU: STU288_15785
SETC: CFSAN001921_01430
SENI: CY43_16260
SEI: SPC_3186
SEC: SCH_3059(maoC)
SHB: SU5_03617
SED: SeD_A3463
SEG: SG3013
SEL: SPUL_3122
SET: SEN2962
SENA: AU38_15055
SENO: AU37_15065
SENV: AU39_15060
SENQ: AU40_16975
SENL: IY59_15665
SEEP: I137_14920
SENE: IA1_15055
YPE: YPO1927
YPK: y2384
YPA: YPA_1305
YPM: YP_1669(maoC)
YPD: YPD4_1694
YPX: YPD8_1854
YPW: CH59_3723
YPV: BZ15_1615
YPL: CH46_3188
YPS: YPTB1925
YPO: BZ17_546
YPY: YPK_2267
YPB: YPTS_1974
YPQ: DJ40_390
YPU: BZ21_1196
YPR: BZ20_193
YPC: BZ23_1479
YPF: BZ19_1271
SPE: Spro_3023
SOD: Sant_0822
PAE: PA0878
PAEV: N297_906
PAEI: N296_906
PAEP: PA1S_22050
PAEM: U769_21420
PAEL: T223_22685
PAEG: AI22_11890
PAEC: M802_902
PAEO: M801_906
PMK: MDS_3407
PPSE: BN5_1312
PPI: YSA_10993
PPUN: PP4_26620
PSB: Psyr_2172
PFL: PFL_2647
PPRO: PPC_2696
PFS: PFLU_3476
PFB: VO64_0589
PSA: PST_1693
PKC: PKB_4382
PSES: PSCI_4464
PSEM: TO66_12940
PSIL: PMA3_18295
PALL: UYA_16465
PMAO: PMYSY11_1933(meh)
PAT: Patl_2716
MICC: AUP74_02898(paaZ)
CBU: CBU_0373
CBD: CBUD_1709
CBG: CbuG_1636
CBC: CbuK_0564
LLO: LLO_3026
TMC: LMI_0900
FPZ: LA55_828
FNA: OOM_1390
ADI: B5T_02018
APAC: S7S_06600
BMA: BMAA1652
BMAL: DM55_3232
BMAE: DM78_4162
BMAQ: DM76_3930
BMAI: DM57_07715
BMAF: DM51_3350
BMAZ: BM44_3168
BMAB: BM45_4007
BPS: BPSS1638
BPSE: BDL_4991
BPSM: BBQ_4503
BPSU: BBN_5091
BPSD: BBX_4157
BPK: BBK_4297
BPSH: DR55_3632
BPSA: BBU_4389
BPSO: X996_5998
BUT: X994_5470
BTD: BTI_4119
BOK: DM82_5766
BOC: BG90_4867
BUL: BW21_6125
BXE: Bxe_A4088
PPNO: DA70_04325
PPNM: LV28_01985
PPUL: RO07_25455
CABA: SBC2_62820(mch)
BPE: BP0436
BPC: BPTD_0451
BPER: BN118_0287
BPET: B1917_3383
BPEU: Q425_33750
BAV: BAV0713
BHZ: ACR54_01121(paaZ_1) ACR54_03835
TEA: KUI_1574
TEG: KUK_0905
TAS: TASI_1545
TAT: KUM_1150
PUT: PT7_0055
AMIM: MIM_c40140
POL: Bpro_5294
VEI: Veis_1582
HPSE: HPF_13035(paaZ2)
APET: ToN1_12320
CCQ: N149_0440
CCF: YSQ_07650
CCY: YSS_02005
CCOI: YSU_06660
CCOF: VC76_02320
GEB: GM18_3660
VGO: GJW-30_1_01517(paaZ_1)
SNO: Snov_3518
BID: Bind_2533
CMET: K6K41_24180(ripB)
RBM: TEF_02360
PSF: PSE_3169
CSE: Cseg_2763
SPSE: SULPSESMR1_04108(mch)
HNE: HNE_1098
SPHM: G432_00490
SPHI: TS85_14845
SECH: B18_16040
SFLA: SPHFLASMR4Y_02130(mch)
SMIC: SmB9_17900
ANH: A6F65_00044(paaZ_1)
ADO: A6F68_02606(paaZ_3)
SHUM: STHU_28440
SIV: SSIL_0090
MGA: MGA_1305(maoC)
MGH: MGAH_1305
MGF: MGF_3286
MSY: MS53_0536
MLP: MLM_2703
MUL: MUL_4022
MMI: MMAR_4159
MSAK: MSAS_14220
MBAI: MB901379_00390(phaJ)
MSEO: MSEO_43210
MPSE: MPSD_17120
MSHO: MSHO_16380
MSTE: MSTE_02642
CPSE: CPTA_01733
CPSU: CPTB_02030
CPSF: CPTC_01724
CAQU: CAQU_08895
ROP: ROP_30980
RHB: NY08_70
RFA: A3L23_03454(mch)
RHS: A3Q41_04802(mch)
RHU: A3Q40_00682(mch_1)
SRT: Srot_1098
SGR: SGR_558
STRM: M444_14895
SFK: KY5_1011c
SRJ: SRO_1328
KSK: KSE_23690
MOY: CVS54_01932(mch)
AUW: AURUGA1_01431(paaZ)
ARM: ART_3484
ACIJ: JS278_00425(meh)
NCA: Noca_4064
SRO: Sros_6336
FAL: FRAAL3417
SEN: SACE_2330
AORI: SD37_10620
PSEE: FRP1_16985
SAQ: Sare_2919
CWO: Cwoe_2185
STI: Sthe_1792
ABAS: ACPOL_0784
HTU: Htur_3792
NMG: Nmag_3455
ACJ: ACAM_0232
SOL: Ssol_0875
SSOA: SULA_0911
SSOL: SULB_0913
SSOF: SULC_0912
 » show all
Reference
1  [PMID:4284209]
  Authors
Cooper RA, Kornberg HL.
  Title
The utilization of itaconate by Pseudomonas sp.
  Journal
Biochem J 91:82-91 (1964)
DOI:10.1042/bj0910082
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.56
IUBMB Enzyme Nomenclature: 4.2.1.56
ExPASy - ENZYME nomenclature database: 4.2.1.56
BRENDA, the Enzyme Database: 4.2.1.56
CAS: 37290-83-8

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