KEGG   ENZYME: 4.2.1.56
Entry
EC 4.2.1.56                 Enzyme                                 
Name
itaconyl-CoA hydratase;
itaconyl coenzyme A hydratase;
citramalyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Reaction(IUBMB)
citramalyl-CoA = itaconyl-CoA + H2O [RN:R02490]
Reaction(KEGG)
R02490 > R02491
Substrate
citramalyl-CoA [CPD:C00904]
Product
itaconyl-CoA [CPD:C00531];
H2O [CPD:C00001]
History
EC 4.2.1.56 created 1972
Pathway
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
Orthology
K18290  itaconyl-CoA hydratase
K18291  itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase
Genes
STMSTM3119
SEOSTM14_3768
SEVSTMMW_30791
SEYSL1344_3093
SEMSTMDT12_C31720
SEJSTMUK_3107
SEBSTM474_3268
SEFUMN798_3389
SETUSTU288_15785
SETCCFSAN001921_01430
SENRSTMDT2_30131
SENDDT104_31151
SENICY43_16260
SEENSE451236_21710
SPQSPAB_03889
SEISPC_3186
SECSCH_3059(maoC)
SEHSeHA_C3361
SHBSU5_03617
SENHCFSAN002069_16555
SEEHSEEH1578_01720
SEESNSL254_A3368
SENNSN31241_42430
SEWSeSA_A3294
SEDSeD_A3463
SEGSG3013
SELSPUL_3122
SEGASPUCDC_3108
SETSEN2962
SENAAU38_15055
SENOAU37_15065
SENVAU39_15060
SENQAU40_16975
SENLIY59_15665
SENJCFSAN001992_17980
SEEBSEEB0189_004285
SEEPI137_14920
SENBBN855_31910
SENEIA1_15055
SESSARI_04512
SALZEOS98_03725
YPEYPO1927
YPKy2384
YPAYPA_1305
YPMYP_1669(maoC)
YPPYPDSF_1197
YPGYpAngola_A2117
YPDYPD4_1694
YPXYPD8_1854
YPWCH59_3723
YPVBZ15_1615
YPLCH46_3188
YPSYPTB1925
YPOBZ17_546
YPIYpsIP31758_2157
YPYYPK_2267
YPBYPTS_1974
YPQDJ40_390
YPUBZ21_1196
YPRBZ20_193
YPCBZ23_1479
YPFBZ19_1271
YSIBF17_18435
SPESpro_3023
SLQM495_15430
SQUE4343_00900
SENPKHA73_09775(ripB)
SODSant_0822
XHOA9255_04215
STEKAXG53_18865
LCICINQ41_12735
LAVIINQ42_12365
PAEPA0878
PAEVN297_906
PAEIN296_906
PAUPA14_52910
PAPPSPA7_4636
PAGPLES_44381
PAFPAM18_4161
PNCNCGM2_1656
PAEBNCGM1900_1844
PDKPADK2_21310
PSGG655_20960
PRPM062_04280
PAEPPA1S_22050
PAERPA1R_gp4401
PAEMU769_21420
PAELT223_22685
PAESSCV20265_4646
PAEUBN889_00914
PAEGAI22_11890
PAECM802_902
PAEOM801_906
PMKMDS_3407
PPSEBN5_1312
PCQPcP3B5_31060
PMUIG4G71_15745
PPWPputW619_3045
PPIYSA_10993
PPUNPP4_26620
PFVPsefu_2660
PSBPsyr_2172
PFLPFL_2647
PPRCPFLCHA0_c27140
PPROPPC_2696
PFNHZ99_04650
PFSPFLU_3476
PFCPflA506_2552
PFBVO64_0589
PVRPverR02_17225
PAZOAYR47_23830
PRXHRH33_17880
PFWPF1751_v1c29070
PFFPFLUOLIPICF721650
PFXA7318_12055
PLULFOB45_02105 FOB45_04025
PPUUPputUW4_01806 PputUW4_03342
PDRH681_12245
PSKU771_18565
PKCPKB_4382
PCHEY04_12145
PCZPCL1606_35370
PCPJM49_17725
PPVNJ69_15120
PSESPSCI_4464
PSEMTO66_12940
PKRAYO71_15475
PFKPFAS1_01245
PSILPMA3_18295
PYMAK972_2536
PALLUYA_16465
PGGFX982_03217
PPSHG5J76_13785
PSEJHNQ25_04425 HNQ25_09075
PVKEPZ47_18745
PKHJLK41_17685
PTYJWV26_02665
PMAOPMYSY11_1933(meh)
PVWHU752_018375
PSAMHU731_001135
PPRGHU725_012640
PFAKKSS94_12290
PIEHU724_013970 HU724_013990
PTAENCTC10697_01934
PCAVD3880_17735
PPHNHU825_16730
PIZLAB08_R18810
PPEGKUA23_16525
PSAPST_1693
PSZPSTAB_1603
PSRPSTAA_1723
PSCA458_12240
PSJPSJM300_06605
PSHPsest_2670
PSTUUIB01_13505
PSTTCH92_08205 CH92_21350
PSEDDM292_11100
PCHLLLJ08_12810
PBMCL52_10795
PKGLW136_09765
SDEGGOM96_03895
HPEGEAO82_03715
MARIACP86_19600
THTE2K93_09365
PATPatl_2716
GAGGlaag_1578
PMESFX988_04170
OSGBST96_16095
MICCAUP74_02898(paaZ)
MAGAMag101_09735
MIIBTJ40_11590
MICTFIU95_07925 FIU95_13365 FIU95_13370
MHYDGTQ55_10130
MICZGL2_28700 GL2_28710 GL2_29030
HALCEY643_14920
CBUCBU_0373
CBSCOXBURSA331_A0480
CBDCBUD_1709
CBGCbuG_1636
CBCCbuK_0564
LLOLLO_3026
LSHCAB17_01570
LCJNCTC11976_03021
TMCLMI_0900
FPZLA55_828
FNAOOM_1390
FNLM973_04670
ADIB5T_02018
APACS7S_06600
AXEP40_09650 P40_11605 P40_11615
PTESJQU52_08485
CUHBJN34_09010 BJN34_22935
CTIRALTA_B1741 RALTA_B1743
BMABMAA1652
BMVBMASAVP1_1726
BMLBMA10229_1932
BMNBMA10247_A0609
BMALDM55_3232
BMAEDM78_4162
BMAQDM76_3930
BMAIDM57_07715
BMAFDM51_3350
BMAZBM44_3168
BMABBM45_4007
BPSBPSS1638
BPMBURPS1710b_A0702
BPLBURPS1106A_A2221
BPDBURPS668_A2304
BPSEBDL_4991
BPSMBBQ_4503
BPSUBBN_5091
BPSDBBX_4157
BPZBP1026B_II1752
BPQBPC006_II2199
BPKBBK_4297
BPSHDR55_3632
BPSABBU_4389
BPSOX996_5998
BUTX994_5470
BTDBTI_4119
BOKDM82_5766
BOCBG90_4867
BSAVWS86_27025
BHGI6G56_32450
BULBW21_6125
BUDAQ610_22590
BUMAXG89_23910 AXG89_28780 AXG89_40395
BUIAX768_19490
BXEBxe_A4088
BXBDR64_1764 DR64_7611
BPYBphyt_0612
PARBCJU94_03205
PTERC2L65_44455
PACSFAZ98_15395
PDIOPDMSB3_0446
PPKU875_11925
PPNODA70_04325
PPNMLV28_01985
PRBX636_22780
PPULRO07_25455
PTXABW99_05285
PANDDRB87_09750 DRB87_14365
PLGNCTC10937_02755
CABASBC2_62820(mch)
BPEBP0436
BPCBPTD_0451
BPERBN118_0287
BPETB1917_3383
BPEUQ425_33750
BPARBN117_0456 BN117_1032
BPABPP0463 BPP3645
BBHBN112_2949 BN112_4323
BBRBB0463 BB4080
BBMBN115_0450 BN115_3769
BBXBBS798_0460 BBS798_3873
BPTBpet0818 Bpet0844
BAVBAV0713
BHOD560_0129 D560_1020
BHMD558_0125 D558_1006
BHZACR54_01121(paaZ_1) ACR54_03835
BTRMSAMEA390648700436
BPDZBBN53_03945
BOHAKI39_05280
BGMCAL15_19455
AXYAXYL_00899
AXONH44784_012421
AXNAX27061_0915
AXXERS451415_00902
ADTAPT56_04800
AISBUW96_21195
ASWCVS48_01860
ACHRC2U31_09190
ACHBDVB37_03995
ADYHLG70_17360
ACHOH4P35_04015
TEQTEQUI_0591
TEAKUI_1574
TEGKUK_0905
TASTASI_1545
TATKUM_1150
PUTPT7_0055
PUSCKA81_09520
AKATKWG_24830
AMIMMIM_c40140
BOZDBV39_05635 DBV39_17790
OURCEQ07_11010
OUEI6G29_06915
PIGEGT29_18075 EGT29_20245
PARKLSG25_07870 LSG25_20015
RFRRfer_4170 Rfer_4180
RHFEUB48_16960
POLBpro_5294
VEIVeis_1582
DELDelCs14_1625 DelCs14_1627
ADNAlide_0527 Alide_3398
ADKAlide2_0484 Alide2_1037
HYRBSY239_2753
HPSEHPF_13035(paaZ2)
MNRACZ75_13500 ACZ75_18265
XYKGT347_03980
APETToN1_12320
BEBAEM42_06475
CCCG157_06430
CCQN149_0440
CCFYSQ_07650
CCYYSS_02005
CCOIYSU_06660
CCOFVC76_02320
CCOOATE51_03328
GEBGM18_3660
GERKP004_02745
GSUBKP001_12705
GNTKP003_02380
GPLM1B72_18220
MSDMYSTI_02518 MYSTI_04298
MYMA176_004230
MFBMFUL124B02_13435 MFUL124B02_23085
MFULILAB_26410
MMASMYMAC_003593
AGEAA314_08469
VINAKJ08_0764
RLNJ0663_13765
RLSHB780_13270
VGOGJW-30_1_01517(paaZ_1)
BAPIBBC0122_004680
XDIEZH22_28925
SNOSnov_3518
STARG3545_21885
BIDBind_2533
RHZRHPLAN_27280
DEAFPZ08_20295 FPZ08_20300
CMETK6K41_24180(ripB)
RBMTEF_02360
PSFPSE_3169
PHRC6569_20835
ACUTMRB58_13920
CSECseg_2763
CFHC1707_19790
SPSESULPSESMR1_04108(mch)
SALOEF888_16620
HNEHNE_1098
HBCAEM38_15990
NGFFRF71_11070
NOGGKE62_07625
SGISGRAN_1466 SGRAN_1467
SPHOC3E99_04090 C3E99_04095 C3E99_05325
SPHDHY78_17830 HY78_17840
RDICMV14_20755
SPHMG432_00490
SPHITS85_14845
SPANAWL63_23770
SECHB18_16040
SLANGV829_06060
SAERNEF64_09100
SCHSphch_2118
SFLASPHFLASMR4Y_02130(mch)
SPHYCHN51_04325
SPHLLPB140_01050
BLASBSY18_2912 BSY18_3093
BFWB5J99_05640 B5J99_06505
PALGHFP57_14280
PARJJ4G78_13065
PHAOHF685_09495
SMICSmB9_17900
SANDH3309_06830
ALHG6N82_04765
ANHA6F65_00044(paaZ_1)
ADOA6F68_02606(paaZ_3)
EGNBMF35_a1281
ELQGa0102493_11612
PHZCHX26_06045
SHUMSTHU_28440
SVCSTVA_32330
STELSTAQ_25590
ABSAZOBR_p460036
ABQABAZ39_31965
ABFAMK58_24905 AMK58_27770
AZTTSH58p_20920
NCBC0V82_13805 C0V82_17290
TMOTMO_a0440 TMO_a0442 TMO_b0388
HADHFRZ61_45880
PARHI5S86_16400 I5S86_16845
ASEDIRT44_09900
RUEDT065_03735
SALEEPH95_03505
SCIBHUG20_10875
SCIAHUG15_13410
BCOPJD108_17245
SIVSSIL_0090
SSILSOLI23_18375
MTUYH3143_01770
MSYMS53_0536
MSOVY93_02915
MGAMGA_1305(maoC)
MGHMGAH_1305
MGFMGF_3286
MIWEER00_03360
MLPMLM_2703
MULMUL_4022
MMIMMAR_4159
MMAEMMARE11_39690
MLIMULP_04327
MPSEMPSD_17120
MSHOMSHO_16380
MGOAFA91_09670
MSAKMSAS_14220
MBAIMB901379_00390(phaJ)
MSEOMSEO_43210
MLJMLAC_39600
MSTEMSTE_02642
CPUCPFRC_05850
CPLCp3995_1184
CPGCP316_06000
CPPCpP54B96_1180
CPKCP1002_07295
CPQCPC231_05855
CPXCPI19_05665
CPZCpPAT10_1157
CORCp267_1212
COPCP31_06230
CODCp106_1142
COSCp4202_1151
COICPCIP5297_06015
COECP258_06010
COUCP162_05280
CPSECPTA_01733
CPSUCPTB_02030
CPSFCPTC_01724
CMDB841_00430
CAQUCAQU_08895
COKCOCCU_01040
NNONONO_c35120
NOZDMB37_03985
NIEKV110_07705 KV110_22130
ROPROP_30980
ROAPd630_LPD07081 Pd630_LPD07625
RPYY013_25540
RHBNY08_70
RFAA3L23_03454(mch)
RHSA3Q41_04802(mch)
RHUA3Q40_00682(mch_1)
GTABCM27_00330
GRUGCWB2_00255
GAVC5O27_04375
GODGKZ92_00500
GHNMVF96_00300
GAMIIHQ52_03920
SRTSrot_1098
SGRSGR_558
SRCM271_41105 M271_49660
SBHSBI_00757 SBI_09088
STRMM444_14895
SCADDN051_00530 DN051_40280
SNWBBN63_32945
SFKKY5_1011c
SRJSRO_1328
STIRDDW44_01555
SKACP970_37850
SFICEIZ62_01245
SSPODDQ41_10335
SGFHEP81_01295
SBATG4Z16_30040
SVDCP969_00525
KSKKSE_23690
KABB7C62_13320
KAUB6264_30520
KITCFP65_5905
STRIC7M71_005355
MIMAKG07_03660
MIPAXH82_14610
MICRBMW26_08260
MOYCVS54_01932(mch)
AMINAUMI_115630
AUWAURUGA1_01431(paaZ)
HEAHL652_17025 HL652_17030
SUBALQ955_13915 LQ955_17435
ARMART_3484
ARZAUT26_01545
ARXARZXY2_3555
ARTPE5206_12360
ARTYAHiyo4_01850
PEIH9L10_10385
ACIJJS278_00425(meh)
NCANoca_4064
NOIFCL41_07655
NAROCFH99_24510
MUZH4N58_19260
SROSros_6336
NOABKM31_26125
NGNLCN96_20470
FALFRAAL3417
SENSACE_2330
AMYCCU254_42145
AORISD37_10620
PDXPsed_0099 Psed_4113 Psed_6732
PSEEFRP1_16985
PSEQAD006_24435
PECQAD017_04025
PHHAFB00_22120
PAUTPdca_22270 Pdca_38310
PMADBAY61_15180
STPStrop_0462 Strop_1721
SAQSare_2919
MICHFJK98_21010
MCRAID554_06815
AMSAMIS_57130
PLKCIK06_17820 CIK06_17825 CIK06_24305
VERHUT12_06145
PRYPrubr_51730
EKEEK0264_19105
RXYRxyl_0670 Rxyl_2737
RRDRradSPS_1705
RUBGBA63_03935
BSOLFSW04_07165 FSW04_11420
CWOCwoe_2185
ERZER308_17470
STISthe_1792
PBFCFX0092_B0383
ABASACPOL_0784
ARACE0W69_008615
HAGSJT689_10595
HJEHacjB3_13725
HSUHLASF_0426
HSFHLASA_0424
SALRFQU85_08755
HALXM0R89_21420
NHOHWV23_12055
NSALHWV07_13725
HALIBV210_16875
SSAIN0B31_11010
HAQDU484_05285
HAJDU500_05725
HRAEI982_05240
HALBEKH57_10330
HALQHrr1229_005595
HSAIHPS36_05590
SRUBC2R22_10080
HALGHUG10_11570
HALUHUG12_00295 HUG12_04285
HMPK6T50_17560
HREK6T36_16465
HAHHalar_0325
HTUHtur_3792
HDABB347_13355
NMGNmag_3455
NPENatpe_1337
NVRFEJ81_07125
NAYHYG81_23810
HJTDVR14_15860
NGENatgr_2181
NOUNatoc_4274
NBGDV706_20325 DV706_21415
NASGCU68_04235 GCU68_20760
ACJACAM_0232
SOLSsol_0875
SSOASULA_0911
SSOLSULB_0913
SSOFSULC_0912
SACNSacN8_05275
SACRSacRon12I_05265
SACSSUSAZ_05040
SULEGFS03_12045
MEMJMJ1HA_1378
AMANB6F84_05460
ABRIDFR85_14460
SACDHS1genome_2007
 » show all
Reference
1  [PMID:4284209]
  Authors
Cooper RA, Kornberg HL.
  Title
The utilization of itaconate by Pseudomonas sp.
  Journal
Biochem J 91:82-91 (1964)
DOI:10.1042/bj0910082
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.56
IUBMB Enzyme Nomenclature: 4.2.1.56
ExPASy - ENZYME nomenclature database: 4.2.1.56
BRENDA, the Enzyme Database: 4.2.1.56
CAS: 37290-83-8

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