| Entry |
|
|---|
| Name |
scytalone dehydratase;
scytalone 7,8-hydro-lyase
|
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
 |
|---|
| Sysname |
scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)
|
|---|
| Reaction(IUBMB) |
scytalone = 1,3,8-trihydroxynaphthalene + H2O [RN: R02907]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
Involved, with EC 1.1.1.252 tetrahydroxynaphthalene reductase, in the biosynthesis of melanin in pathogenic fungi.
|
|---|
| History |
EC 4.2.1.94 created 1992
|
|---|
| Orthology |
|
|---|
| Genes |
» show all
 |
|---|
| Reference |
1 |
|---|
| Authors |
Butler, M.J., Lazarovits, G., Higgins, V.J. and Lachance, M.-A. |
|---|
| Title |
Partial-purification and characterization of a dehydratase associated with the pentaketide melanogenesis pathway of Phaeococcomyces sp and other fungi. |
|---|
| Journal |
Exp Mycol 12:367-376 (1988) |
|---|
| Reference |
2 |
|---|
| Authors |
Tajima, S., Kubo, Y., Furusawa, I. and Shishiyama, J. |
|---|
| Title |
Purification of a melanin biosynthetic enzyme converting scytalone to 1,3,8-trihydroxynaphthalene from Cochliobolus miyabeanus. |
|---|
| Journal |
Exp Mycol 13:69 (1989) |
|---|
| Reference |
3 |
|---|
| Authors |
Wheeler, M.H. and Greenblatt, G.A. |
|---|
| Title |
The inhibition of melanin biosynthetic reactions in Pyricularia oryzae by compounds that prevent rice blast disease. |
|---|
| Journal |
Exp Mycol 12:151-160 (1988) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.1.94 |
| ExPASy - ENZYME nomenclature database: | 4.2.1.94 |
|
|---|
