KEGG   ENZYME: 4.2.2.9
Entry
EC 4.2.2.9                  Enzyme                                 
Name
pectate disaccharide-lyase;
pectate exo-lyase;
exopectic acid transeliminase;
exopectate lyase;
exopolygalacturonic acid-trans-eliminase;
PATE;
exo-PATE;
exo-PGL;
exopolygalacturonate lyase (ambiguous);
pelW (gene name);
pelX (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
Sysname
(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase
Reaction(IUBMB)
(1,4-alpha-D-galacturonosyl)n = (1,4-alpha-D-galacturonosyl)n-2 + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [RN:R02361 R06240]
Reaction(KEGG)
R02361 R06240(G)
Substrate
(1,4-alpha-D-galacturonosyl)n [CPD:C00470]
Product
(1,4-alpha-D-galacturonosyl)n-2;
4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [CPD:C06118]
Comment
The enzyme catalyses the eliminative cleavage of an unsaturated disaccharide from the reducing end of homogalacturonan (the backbone of smooth regions of pectate, also known as de-esterified pectin).
History
EC 4.2.2.9 created 1972, modified 2002
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K01731  pectate disaccharide-lyase
K22994  pectate disaccharide-lyase
Genes
ECC: c0323
EAB: ECABU_c02850
ELC: i14_0311
ELD: i02_0311
ECAN: CWI88_22765
ENT: Ent638_4134
EAS: Entas_4441
ENR: H650_15125
ENF: AKI40_4954
EHU: D5067_0023365
KOX: KOX_06695
KOE: A225_5810
KOY: J415_03050
KOM: HR38_05185
KOK: KONIH1_29285
KOC: AB185_07140
KLL: BJF97_28845
KLW: DA718_29440
KGR: JJJ10_27690
KPAS: LUW96_06665
KLC: K7H21_27895
KLM: BWI76_00175
REE: electrica_05046(pelX)
ROR: RORB6_18635
RON: TE10_02310
RAO: DSD31_25725
RTG: NCTC13098_07214(pelX)
KSA: C813_15435
KOR: AWR26_24550
KRD: A3780_24760
KCO: BWI95_07865
KOT: EH164_22305
KPSE: IP581_23260
KOB: HF650_24205
KOO: O9K67_24495
KOU: C0557_26245
KIE: NCTC12125_03774(pelX)
KAS: KATP_45140
KLU: K7B04_05140
KCY: RIN60_22700
LAX: APT61_22190
LEI: C2U54_04755
LEH: C3F35_11740
LEE: DVA44_23660
LER: GNG29_23015
LEA: GNG26_22355
LPNU: KQ929_20635
LEY: DVA43_17990
LAZ: A8A57_00130
LEF: LJPFL01_4267
BAGE: BADSM9389_41930
SYM: K6K13_10740
IZH: FEM41_05575
PSGC: G163CM_35660(pelX)
EBF: D782_4530
YPE: YPO1723(kdgC)
YPK: y1885
YPH: YPC_2093(kdgC)
YPA: YPA_1798
YPN: YPN_1907
YPM: YP_1748(pelW)
YPP: YPDSF_1725
YPG: YpAngola_A2644
YPZ: YPZ3_1982(pelW)
YPT: A1122_17265
YPD: YPD4_1533(pelW)
YPX: YPD8_2019(pelW)
YPW: CH59_111
YPJ: CH55_525
YPV: BZ15_1826
YPL: CH46_3400
YPS: YPTB2358(pelW)
YPO: BZ17_98
YPI: YpsIP31758_1692
YPY: YPK_1802
YPB: YPTS_2432
YPQ: DJ40_4215
YPU: BZ21_1644
YPR: BZ20_3849
YPC: BZ23_1930
YPF: BZ19_1721
YEN: YE1886(kdgC)
YEP: YE105_C1965
YEY: Y11_07571
YEW: CH47_1320
YET: CH48_3593
YEF: FORC2_2251
YEE: YE5303_20681(kdgC)
YSI: BF17_20920
YAL: AT01_227
YFR: AW19_1431
YIN: CH53_4262
YKR: CH54_231
YRO: CH64_775
YMA: DA391_10370
YHI: D5F51_07675
YEL: LC20_03007
YCA: F0T03_09890
YMO: HRD69_14695
YAS: N0H69_13100
YKI: HRD70_14500
YEG: PL78_18965
SFW: WN53_25785
SFG: AV650_21450
SOF: NCTC11214_03558(pelX_3)
RAH: Rahaq_4460
RACE: JHW33_24235
RAQ: Rahaq2_4938
RAA: Q7S_22851
ROX: BV494_21955
RVC: J9880_22120
RBON: QNM34_10420
RIU: I2123_22210
RBAD: H2866_18360
SERA: Ser39006_002560 Ser39006_014590
SERQ: CWC46_02560 CWC46_14585
ECA: ECA2402(pelW) ECA4510(pelX)
PATR: EV46_11575 EV46_22450
PATO: GZ59_21550(pelW) GZ59_46090(pelX)
PCT: PC1_1908 PC1_4259
PCC: PCC21_019680 PCC21_042370
PCV: BCS7_09865 BCS7_21380
PWA: Pecwa_2201 Pecwa_4562
PPAR: A8F97_07605 A8F97_18635
PEC: W5S_2143 W5S_4748
PWS: A7983_07710 A7983_18435
PPOA: BJK05_04570 BJK05_16445
PBRA: B5S52_12135 B5S52_22085
PPUJ: E2566_10205 E2566_21650
PARI: I2D83_10380 I2D83_22075
PAQU: DMB82_0011465 DMB82_0020540
PVZ: OA04_23530(pelW) OA04_45670(pelX)
PPAV: LOZ86_00635 LOZ86_09635
PQU: IG609_009430 IG609_020225
PPOO: LW347_09980 LW347_21675
PCAC: OI450_10055 OI450_18445
PACB: M9782_02195 M9782_12065
PARL: PEC302110_19040 PEC302110_40790
PPEU: DUT67_11560(pelW) DUT67_22070(pelX)
DDD: Dda3937_00143(pelX) Dda3937_03361(pelW)
DZE: Dd1591_1970 Dd1591_4196
DDC: Dd586_1962 Dd586_4161
DZC: W909_10230 W909_20195
DSO: A4U42_08850 A4U42_20320
CED: LH89_00845 LH89_12570
DFN: CVE23_11925 CVE23_22315
DDQ: DDI_2102 DDI_4246
DAQ: DAQ1742_02459(pelW) DAQ1742_04477(pelX)
DIC: Dpoa569_001819 Dpoa569_003915
DLC: O1Q98_02975 O1Q98_11655
DDA: Dd703_2033 Dd703_3996
BGJ: AWC36_08305
BNG: EH206_11725
BIZ: HC231_10285
PROD: PCO85_10355 PCO85_22815
EPE: CI789_19155
ERWI: GN242_00350
ERP: LJN55_00455
ETO: RIN69_06505
PALH: B1H58_13815
PGZ: C2E15_14280
PCD: C2E16_14360
MINT: C7M51_02053(pelX)
MTHI: C7M52_00789(pelX)
MHAN: K6958_13825
MSU: MS1742
BSUN: A4G13_06040
ASU: Asuc_1469
VVY: VVA1380 VVA1383
VVM: VVMO6_04291 VVMO6_04295
VVL: VV93_v1c42910 VV93_v1c42940
VPA: VPA0086
VPB: VPBB_A0079
VPK: M636_07910
VPH: VPUCM_20080
VEX: VEA_000914
VFU: vfu_B01220 vfu_B01227
VFL: AL536_00985 AL536_01015
VGA: BSQ33_05600 BSQ33_05635
VSR: Vspart_02703(pelW) Vspart_02709(pelX)
VZI: G5S32_19215 G5S32_19245
VOS: KNV97_03645 KNV97_03675
VRU: RND59_09240 RND59_09270
PPR: PBPRB1725(PELX)
PGB: H744_1c0411
PGH: FH974_23475
GAP: GAPWK_0007
GAQ: RAM11_01195
BACA: FAY30_24085
BHA: BH0494(pelX)
BKW: BkAM31D_11885(pelX)
HLI: HLI_08040
NNV: QNH39_24045
SEDD: ERJ70_07430
RMF: D5E69_01130
CTHU: HUR95_16465
PCX: LPB68_01775
EFC: EFAU004_00534
EFAU: EFAU085_00472
EFU: HMPREF0351_10547(fms12)
EFT: M395_02570
EDU: LIU_03960
ELAC: I4Q40_02775
MPS: MPTP_1486
MPX: MPD5_0537
JEH: EJN90_07475
CCB: Clocel_2642 Clocel_3380
CSR: Cspa_c44020(pelX)
CBUT: ATN24_17765
CRW: CROST_043480
CFB: CLFE_004550
CSS: Cst_c01730(pelX)
CSD: Clst_0166(pelA)
FPR: FP2_32150
BPEN: NQ488_12040
CPY: Cphy_3869
LGG: QJR73_03050
ACEL: acsn021_18180
EEL: EUBELI_00122
CLE: Clole_0686
CEW: EKH84_06800
TIT: Thit_1727
HALS: D7D81_06930
IFN: GM661_04520
COW: Calow_2109
TSG: HLK68_02840
ABRA: BN85302860
SGRF: SGFS_070080
SXI: SXIM_19900
SPAD: DVK44_19990
SHAR: HUT13_08720
AGY: ATC03_04075
IVA: Isova_1147
IDO: I598_2859(pelX)
SKE: Sked_26480
SANW: G7063_10785
TBE: Trebr_2157
TRI: DYE50_02030 DYE50_12275
SCD: Spica_0639
FMO: C4N19_12110
TTA: Theth_1384
 » show all
Reference
1  [PMID:14188174]
  Authors
MACMILLAN JD, VAUGHN RH.
  Title
PURIFICATION AND PROPERTIES OF A POLYGALACTURONIC ACID-TRANS-ELIMINASE PRODUCED BY CLOSTRIDIUM MULTIFERMENTANS.
  Journal
Biochemistry 3:564-72 (1964)
DOI:10.1021/bi00892a016
Reference
2  [PMID:10049400]
  Authors
Shevchik VE, Kester HC, Benen JA, Visser J, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
Characterization of the exopolygalacturonate lyase PelX of Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:1652-63 (1999)
DOI:10.1128/JB.181.5.1652-1663.1999
  Sequence
[ag:CAB39324]
Reference
3  [PMID:10383957]
  Authors
Shevchik VE, Condemine G, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
The exopolygalacturonate lyase PelW and the oligogalacturonate lyase Ogl, two cytoplasmic enzymes of pectin catabolism in Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:3912-9 (1999)
DOI:10.1128/JB.181.13.3912-3919.1999
  Sequence
[ddd:Dda3937_03361]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.2.9
IUBMB Enzyme Nomenclature: 4.2.2.9
ExPASy - ENZYME nomenclature database: 4.2.2.9
BRENDA, the Enzyme Database: 4.2.2.9
CAS: 37290-87-2

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Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (2)   
   KEGG GLYCAN (2)   
Chemical reaction (4)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (1331)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (292)   
   KEGG MGENES (1032)   
   RefGene (5)   
Protein sequence (691)   
   UniProt (142)   
   SWISS-PROT (2)   
   RefSeq(pep) (547)   
DNA sequence (1776)   
   RefSeq(nuc) (1530)   
   GenBank (128)   
   EMBL (118)   
Protein domain (5)   
   InterPro (5)   
All databases (3815)   

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