KEGG ENZYME: 4.2.3.117

ENZYME: 4.2.3.117

Entry

EC 4.2.3.117                Enzyme

Name

(-)-camphene synthase;
CS

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-camphene-forming]

Reaction(IUBMB)

geranyl diphosphate = (-)-camphene + diphosphate [RN:R09972]

Reaction(KEGG)

R09972

Substrate

geranyl diphosphate [CPD:C00341]

Product

(-)-camphene [CPD:C06305];
diphosphate [CPD:C00013]

Comment

(-)-Camphene is the major product in Abies grandis (grand fir) with traces of other monoterpenoids [1]. In Pseudotsuga menziesii (Douglas-fir) there are about equal parts of (-)-camphene and (-)-alpha-pinene with traces of four other monoterpenoids [2,3]. In Solanum lycopersicum (tomato) tricyclene, beta-myrcene, limonene, and traces of several other monoterpenoids are also formed [4]. See also EC 4.2.3.15 myrcene synthase, EC 4.2.3.16 (4S)-limonene synthase, EC 4.2.3.119 (-)-alpha-pinene synthase and EC 4.2.3.105 tricyclene synthase.

History

EC 4.2.3.117 created 2012

Pathway

ec00902

Monoterpenoid biosynthesis

ec01100

Metabolic pathways

Orthology

K21925

(-)-camphene/tricyclene/(4S)-limonene/myrcene synthase

K22208

(-)-camphene synthase

Genes

SLY:	101245212(TPS3) 101249864

SPEN:

107012939 107012948

SOT:	102591915 102602070

CANN:

107840093

NTA:	107785945 107787835

NSY:

104238653

NTO:

104090536

NAU:

109214608

SSPL:

121755010

Reference

1 [PMID:10441373]

Authors

Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R

Title

cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis).

Journal

Arch Biochem Biophys 368:232-43 (1999)
DOI:10.1006/abbi.1999.1332

Sequence

[ag:AAB70707]

Reference

2 [PMID:15921711]

Authors

Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J

Title

Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii.

Journal

Phytochemistry 66:1427-39 (2005)
DOI:10.1016/j.phytochem.2005.04.030