Entry |
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Name |
gamma-muurolene synthase;
Cop3
|
Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lase (cyclizing, gamma-muurolene-forming)
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Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = gamma-muurolene + diphosphate [RN: R10005]
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Reaction(KEGG) |
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Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
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Product |
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Comment |
The enzyme has been characterized from the fungus Coprinus cinereus. Also gives germacrene A and alpha-muurolene, see EC 4.2.3.23, germacrene-A synthase and EC 4.2.3.125, alpha-muurolene synthase.
|
History |
EC 4.2.3.126 created 2012
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Orthology |
K21927 | alpha-muurolene/germacrene-A/gamma-muurolene synthase |
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Genes |
» show all
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Reference |
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Authors |
Agger S, Lopez-Gallego F, Schmidt-Dannert C |
Title |
Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus. |
Journal |
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Sequence |
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Reference |
|
Authors |
Lopez-Gallego F, Wawrzyn GT, Schmidt-Dannert C |
Title |
Selectivity of fungal sesquiterpene synthases: role of the active site's H-1 alpha loop in catalysis. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 4.2.3.126 |
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