KEGG ENZYME: 4.2.3.144

ENZYME: 4.2.3.144

Entry

EC 4.2.3.144                Enzyme

Name

geranyllinalool synthase;
TPS04/GES;
GES

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

geranylgeranyl-diphosphate diphosphate-lyase [(E,E)-geranyllinalool-forming]

Reaction(IUBMB)

geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate [RN:R10533]

Reaction(KEGG)

R10533

Substrate

geranylgeranyl diphosphate [CPD:C00353];
H2O [CPD:C00001]

Product

(6E,10E)-geranyllinalool [CPD:C20681];
diphosphate [CPD:C00013]

Comment

The enzyme is a component of the herbivore-induced indirect defense system. The product, (E,E)-geranyllinalool, is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT), which is released by many plants in response to damage.

History

EC 4.2.3.144 created 2013

Pathway

ec00904

Diterpenoid biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K17982

geranyllinalool synthase

Genes

ATH:	AT1G61120(TPS04)

ALY:

9322626

CRB:

17894892

CSAT:

104716016 104754111

EUS:	EUTSA_v10023261mg

BRP:

103838542

BNA:	106394830 106421978

BOE:

106317451

RSZ:	108825402 108828927

THJ:

104819156

CIT:

102615273

CIC:	CICLE_v10014262mg

PVY:

116145933

MINC:

123218154 123218155

TCC:

18596906

HSYR:

120121786 120192372

DZI:

111318761

GMX:	100801909(TPS17)

GSJ:

114375850

VUM:

124833890

APRC:

113852067 113859895

QSA:	O6P43_012599

PDUL:

117621951

MSYL:

126610088

MNT:

21395364

CSAV:

115696241 115696242

JCU:

105649498

HBR:

110643009

MESC:

110605412

POP:

7494350

PEU:

105128087

PALZ:

118047351 118058321

JRE:	108980512 108980515

CILL:

122275634 122277255

CAVE:

132168887 132169898

TWL:	119987749 119989959

VVI:	100255330 100264943

VRI:	117923513 117924119 117924226 117924269 117924274

SLY:

101262489

SPEN:

107015071

SOT:

102599238

SSTN:

125860537

SDUL:

129896507

LBB:

132618871

ITR:

116028365

SSPL:

121742651 121744697 121789493

SMIL:

130985542

SHIS:

125187743 125209176

APAN:

127249780

ECAD:

122582386

CSIN:

114267916 114295608 114295609 114318211

RVL:	131312085 131312779 131312780 131317277

AEW:	130782577 130795146

ATRI:

130816048

MOF:	131145713 131145715 131145718 131153769

MING:

122075207

TSS:

122650729

ZOF:	121972243 121978100

MSIN:

131221945 131221946 131221957 131221960 131221962 131241231 131241232

» show all

Reference

1 [PMID:18398052]

Authors

Herde M, Gartner K, Kollner TG, Fode B, Boland W, Gershenzon J, Gatz C, Tholl D

Title

Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT.

Journal

Plant Cell 20:1152-68 (2008)
DOI:10.1105/tpc.106.049478

Sequence

[ath:AT1G61120]

Reference

2 [PMID:18842097]

Authors

Attaran E, Rostas M, Zeier J

Title

Pseudomonas syringae elicits emission of the terpenoid (E,E)-4,8,12-trimethyl-1,3,7,11-tridecatetraene in Arabidopsis leaves via jasmonate signaling and expression of the terpene synthase TPS4.

Journal

Mol Plant Microbe Interact 21:1482-97 (2008)
DOI:10.1094/MPMI-21-11-1482

Sequence

[ath:AT1G61120]

Other DBs

ExplorEnz - The Enzyme Database:

4.2.3.144

IUBMB Enzyme Nomenclature:

4.2.3.144

ExPASy - ENZYME nomenclature database:

4.2.3.144

BRENDA, the Enzyme Database:

4.2.3.144

DBGET integrated database retrieval system