KEGG   ENZYME: 4.2.3.144
Entry
EC 4.2.3.144                Enzyme                                 

Name
geranyllinalool synthase;
TPS04/GES;
GES
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranylgeranyl diphosphate diphosphate-lyase ((E,E)-geranyllinalool-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate [RN:R10533]
Reaction(KEGG)
R10533
Substrate
geranylgeranyl diphosphate [CPD:C00353];
H2O [CPD:C00001]
Product
(6E,10E)-geranyllinalool [CPD:C20681];
diphosphate [CPD:C00013]
Comment
The enzyme is a component of the herbivore-induced indirect defense system. The product, (E,E)-geranyllinalool, is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT), which is released by many plants in response to damage.
History
EC 4.2.3.144 created 2013
Pathway
ec00904  Diterpenoid biosynthesis
Orthology
K17982  geranyllinalool synthase
Genes
ATH: AT1G61120(TPS04)
CRB: 17894892
CSAT: 104716016 104754111
EUS: EUTSA_v10023261mg
BNA: 106394830 106421978
BOE: 106317451
CIT: 102615273
CIC: CICLE_v10014262mg
GMX: 100801909(GMTPS17)
GSJ: 114375850
SLY: 101262489
SPEN: 107015071
SOT: 102599238
 » show all
Reference
1  [PMID:18398052]
  Authors
Herde M, Gartner K, Kollner TG, Fode B, Boland W, Gershenzon J, Gatz C, Tholl D
  Title
Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT.
  Journal
Plant Cell 20:1152-68 (2008)
DOI:10.1105/tpc.106.049478
  Sequence
[ath:AT1G61120]
Reference
2  [PMID:18842097]
  Authors
Attaran E, Rostas M, Zeier J
  Title
Pseudomonas syringae elicits emission of the terpenoid (E,E)-4,8,12-trimethyl-1,3,7,11-tridecatetraene in Arabidopsis leaves via jasmonate signaling and expression of the terpene synthase TPS4.
  Journal
Mol Plant Microbe Interact 21:1482-97 (2008)
DOI:10.1094/MPMI-21-11-1482
  Sequence
[ath:AT1G61120]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.144
IUBMB Enzyme Nomenclature: 4.2.3.144
ExPASy - ENZYME nomenclature database: 4.2.3.144
BRENDA, the Enzyme Database: 4.2.3.144

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