KEGG   ENZYME: 4.2.3.169
Entry
EC 4.2.3.169                Enzyme                                 
Name
7-epi-alpha-eudesmol synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-alpha-eudesmol-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = 7-epi-alpha-eudesmol + diphosphate [RN:R11834]
Reaction(KEGG)
R11834
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
7-epi-alpha-eudesmol [CPD:C21689];
diphosphate [CPD:C00013]
Comment
The enzyme, found in the bacterium Streptomyces viridochromogenes, is specific for (2E,6E)-farnesyl diphosphate.
History
EC 4.2.3.169 created 2017
Orthology
K28674  7-epi-alpha-eudesmol synthase
Genes
SFA: Sfla_4535
STRP: F750_2155
SGU: SGLAU_29930
SCW: TU94_31360
SAMB: SAM23877_6746
SLE: sle_05460(sle_05460)
SPAV: Spa2297_29830
SCAD: DN051_06120
SLAU: SLA_0300
SVQ: N6Q81_31120
SDX: C4B68_03315
SGD: ELQ87_03010
SAST: CD934_31940
SNQ: CP978_29965
SFY: GFH48_05405
SPAC: B1H29_03355
SCOE: CP976_39030
SSPB: CP982_04745
STUI: GCM10017668_04680
SPRA: CP972_32765
SLF: JEQ17_06745
SAOV: G3H79_01155
SLAI: P8A22_06155
SCAY: PYS65_01440
SGLY: P8A20_26290
STRV: EZV63_34125
SFLU: ACKTSN_03215
STRK: R2B38_39430
 » show all
Reference
1  [PMID:27829890]
  Authors
Rabe P, Schmitz T, Dickschat JS
  Title
Mechanistic investigations on six bacterial terpene cyclases.
  Journal
Beilstein J Org Chem 12:1839-1850 (2016)
DOI:10.3762/bjoc.12.173
  Sequence
[ag:WP_003994861]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.169
IUBMB Enzyme Nomenclature: 4.2.3.169
ExPASy - ENZYME nomenclature database: 4.2.3.169
BRENDA, the Enzyme Database: 4.2.3.169

  All links  
Protein sequence (637)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (635)   
DNA sequence (1607)   
   RefSeq(nuc) (1537)   
   GenBank (35)   
   EMBL (35)   
All databases (2244)   

Download RDF
DBGET integrated database retrieval system