KEGG   ENZYME: 4.2.3.170
Entry
EC 4.2.3.170                Enzyme                                 
Name
4-epi-cubebol synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 4-epi-cubebol-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = 4-epi-cubebol + diphosphate [RN:R11835]
Reaction(KEGG)
R11835
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
4-epi-cubebol [CPD:C21690];
diphosphate [CPD:C00013]
Comment
The enzyme, found in the bacterium Streptosporangium roseum, is specific for (2E,6E)-farnesyl diphosphate.
History
EC 4.2.3.170 created 2017
Orthology
K23030  4-epi-cubebol synthase
Genes
SRO: Sros_6866
Reference
1  [PMID:27829890]
  Authors
Rabe P, Schmitz T, Dickschat JS
  Title
Mechanistic investigations on six bacterial terpene cyclases.
  Journal
Beilstein J Org Chem 12:1839-1850 (2016)
DOI:10.3762/bjoc.12.173
  Sequence
[sro:Sros_6866]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.170
IUBMB Enzyme Nomenclature: 4.2.3.170
ExPASy - ENZYME nomenclature database: 4.2.3.170
BRENDA, the Enzyme Database: 4.2.3.170

  All links  
Protein sequence (166)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (164)   
DNA sequence (276)   
   RefSeq(nuc) (230)   
   GenBank (23)   
   EMBL (23)   
All databases (442)   

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