KEGG   ENZYME: 4.2.3.181
Entry
EC 4.2.3.181                Enzyme                                 
Name
selina-4(15),7(11)-diene synthase;
SdS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, selina-4(15),7(11)-diene-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = selina-4(15),7(11)-diene + diphosphate [RN:R11846]
Reaction(KEGG)
R11846
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
selina-4(15),7(11)-diene [CPD:C21707];
diphosphate [CPD:C00013]
Comment
Isolated from the bacteria Streptomyces pristinaespiralis and S. somaliensis.
History
EC 4.2.3.181 created 2017
Orthology
K23044  selina-4(15),7(11)-diene synthase
Genes
PFUV: NLK61_04505
MSD: MYSTI_05862
MLAN: JY572_37640
NYA: LTV02_37510
SPRI: SPRI_4868
SRN: A4G23_00263
SGV: B1H19_00030
STIR: DDW44_25060
SGZ: C0216_16010
SRIM: CP984_04900
STSU: B7R87_14380
SBAT: G4Z16_14410
SFB: CP974_01375
SPEU: CGZ69_12110
SGJ: IAG43_10515
STUB: MMF93_01925
SXT: KPP03845_106521
SCHG: NRO40_02035 NRO40_27875
SCHE: QRN89_27550
SSTO: ACE1OC_00990
SLUA: AB8735_37365 AB8735_37840 AB8735_38315
STHU: M1P56_10765
KCM: ABWK59_26390
YIA: LO772_05955
AGLA: OIE69_22260
KBR: Q4V65_42520
 » show all
Reference
1  [PMID:23307484]
  Authors
Rabe P, Dickschat JS
  Title
Rapid chemical characterization of bacterial terpene synthases.
  Journal
Angew Chem Int Ed Engl 52:1810-2 (2013)
DOI:10.1002/anie.201209103
  Sequence
[spri:SPRI_4868]
Reference
2  [PMID:24890698]
  Authors
Baer P, Rabe P, Fischer K, Citron CA, Klapschinski TA, Groll M, Dickschat JS
  Title
Induced-fit mechanism in class I terpene cyclases.
  Journal
Angew Chem Int Ed Engl 53:7652-6 (2014)
DOI:10.1002/anie.201403648
  Sequence
[spri:SPRI_4868]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.181
IUBMB Enzyme Nomenclature: 4.2.3.181
ExPASy - ENZYME nomenclature database: 4.2.3.181
BRENDA, the Enzyme Database: 4.2.3.181

  All links  
Protein sequence (453)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (449)   
DNA sequence (800)   
   RefSeq(nuc) (762)   
   GenBank (19)   
   EMBL (19)   
All databases (1253)   

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