KEGG   ENZYME: 4.2.3.193
Entry
EC 4.2.3.193                Enzyme                                 
Name
(12E)-labda-8(17),12,14-triene synthase;
CldD
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(+)-copalyl-diphosphate diphosphate-lyase [(12E)-labda-8(17),12,14-triene-forming]
Reaction(IUBMB)
(+)-copalyl diphosphate = (12E)-labda-8(17),12,14-triene + diphosphate [RN:R11860]
Reaction(KEGG)
R11860
Substrate
(+)-copalyl diphosphate [CPD:C11901]
Product
(12E)-labda-8(17),12,14-triene [CPD:C21729];
diphosphate [CPD:C00013]
Comment
Isolated from the bacterium Streptomyces cyslabdanicus.
History
EC 4.2.3.193 created 2017
Orthology
K22930  (12E)-labda-8(17),12,14-triene synthase
Reference
1  [PMID:26814669]
  Authors
Yamada Y, Komatsu M, Ikeda H
  Title
Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms.
  Journal
J Antibiot (Tokyo) 69:515-23 (2016)
DOI:10.1038/ja.2015.147
  Sequence
[ag:BAR97453]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.193
IUBMB Enzyme Nomenclature: 4.2.3.193
ExPASy - ENZYME nomenclature database: 4.2.3.193
BRENDA, the Enzyme Database: 4.2.3.193

  All links  
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (2)   
   PDBSTR (4)   
DNA sequence (38)   
   RefSeq(nuc) (38)   
3D Structure (3)   
   PDB (3)   
All databases (49)   

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