KEGG   ENZYME: 4.2.3.196
Entry
EC 4.2.3.196                Enzyme                                 

Name
dolabradiene synthase;
KSL4 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
ent-copalyl-diphosphate diphosphate-lyase (dolabradiene-forming)
Reaction(IUBMB)
ent-copalyl diphosphate = dolabradiene + diphosphate [RN:R12258]
Reaction(KEGG)
R12258
Substrate
ent-copalyl diphosphate [CPD:C06089]
Product
dolabradiene [CPD:C22008];
diphosphate [CPD:C00013]
Comment
The enzyme, which has been characterized from maize, is involved in the biosynthesis of dolabralexins (type of antifungal phytoalexins).
History
EC 4.2.3.196 created 2018
Orthology
K23171  dolabradiene synthase
Genes
ZMA: 100383607(KSL4)
Reference
1  [PMID:29475898]
  Authors
Mafu S, Ding Y, Murphy KM, Yaacoobi O, Addison JB, Wang Q, Shen Z, Briggs SP, Bohlmann J, Castro-Falcon G, Hughes CC, Betsiashvili M, Huffaker A, Schmelz EA, Zerbe P
  Title
Discovery, Biosynthesis and Stress-Related Accumulation of Dolabradiene-Derived Defenses in Maize.
  Journal
Plant Physiol 176:2677-2690 (2018)
DOI:10.1104/pp.17.01351
  Sequence
[zma:100383607]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.196
IUBMB Enzyme Nomenclature: 4.2.3.196
ExPASy - ENZYME nomenclature database: 4.2.3.196
BRENDA, the Enzyme Database: 4.2.3.196

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