KEGG   ENZYME: 4.2.3.2
Entry
EC 4.2.3.2                  Enzyme                                 
Name
ethanolamine-phosphate phospho-lyase;
O-phosphoethanolamine-phospholyase;
amino alcohol O-phosphate phospholyase;
O-phosphorylethanol-amine phospho-lyase;
ethanolamine-phosphate phospho-lyase (deaminating)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
ethanolamine-phosphate phosphate-lyase (deaminating; acetaldehyde-forming)
Reaction(IUBMB)
ethanolamine phosphate + H2O = acetaldehyde + NH3 + phosphate [RN:R00748]
Reaction(KEGG)
R00748
Substrate
ethanolamine phosphate [CPD:C00346];
H2O [CPD:C00001]
Product
acetaldehyde [CPD:C00084];
NH3 [CPD:C00014];
phosphate [CPD:C00009]
Comment
A pyridoxal-phosphate protein. Also acts on D(or L)-1-aminopropan-2-ol O-phosphate.
History
EC 4.2.3.2 created 1972 as EC 4.2.99.7, transferred 2000 to EC 4.2.3.2
Pathway
ec00564  Glycerophospholipid metabolism
ec01100  Metabolic pathways
Orthology
K14286  ethanolamine-phosphate phospho-lyase
Genes
HSA64850(ETNPPL)
PTR461428(ETNPPL)
PPS100969957(ETNPPL)
GGO101144550(ETNPPL)
PON100448531(ETNPPL)
NLE100590020(ETNPPL)
HMH116478756(ETNPPL)
MCC696880(ETNPPL)
MCF102143542(ETNPPL)
MTHB126954932
MNI105486270(ETNPPL)
CSAB103236097(ETNPPL)
CATY105571417(ETNPPL)
PANU101021605(ETNPPL)
TGE112624659(ETNPPL)
MLEU105546581(ETNPPL)
RRO104674699(ETNPPL)
RBB108515462(ETNPPL)
TFN117085767(ETNPPL)
PTEH111547845(ETNPPL)
CANG105514403(ETNPPL)
CJC100395775(ETNPPL)
SBQ101046942(ETNPPL)
CIMI108289680(ETNPPL)
CSYR103254779(ETNPPL)
MMUR105872322(ETNPPL)
LCAT123627743(ETNPPL)
PCOQ105818940(ETNPPL)
OGA100960396(ETNPPL)
MMU71760(Etnppl)
MCAL110291341(Etnppl)
MPAH110320447(Etnppl)
RNO687071(Etnppl)
MCOC116094324(Etnppl)
ANU117707637(Etnppl)
MUN110553305(Etnppl)
CGE100753688(Etnppl)
MAUA101824565(Etnppl)
PROB127223031(Etnppl)
PLEU114682790(Etnppl)
MORG121434998(Etnppl)
MFOT126491596
AAMP119800851(Etnppl)
NGI103742490(Etnppl)
HGL101708633(Etnppl)
CPOC100735915(Etnppl)
CCAN109679845(Etnppl)
DORD105991134(Etnppl)
DSP122127247(Etnppl)
PLOP125341561(Etnppl)
NCAR124994928
MMMA107141381(Etnppl)
OCU100347168
OPI101524508(ETNPPL)
TUP102477402(ETNPPL)
GVR103593697(ETNPPL)
CFA478511(ETNPPL)
CLUD112671628(ETNPPL)
VVP112934214(ETNPPL)
VLG121493274(ETNPPL)
NPO129521237(ETNPPL)
AML100467475(ETNPPL)
UMR103661733(ETNPPL)
UAH113255551(ETNPPL)
UAR123793372(ETNPPL)
ELK111156342
LLV125093271
MPUF101693430(ETNPPL)
MNP132002079(ETNPPL)
MLK131829421(ETNPPL)
NVS122889275(ETNPPL)
ORO101373955(ETNPPL)
EJU114222684(ETNPPL)
ZCA113925836(ETNPPL)
MLX118027083(ETNPPL)
NSU110575518(ETNPPL)
LWW102739736(ETNPPL)
FCA101087400(ETNPPL)
PYU121031390(ETNPPL)
PCOO112858330(ETNPPL)
PBG122477633(ETNPPL)
LRUF124521015
PTG102968560(ETNPPL)
PPAD109247870(ETNPPL)
PUC125923011
AJU106983655
HHV120236137(ETNPPL)
BTA515186(ETNPPL)
BOM102265705(ETNPPL)
BIU109560261(ETNPPL)
BBUB102389697(ETNPPL)
BBIS105002086(ETNPPL)
CHX102185446(ETNPPL)
OAS101120832(ETNPPL)
BTAX128049636(ETNPPL)
ODA120861737(ETNPPL)
CCAD122422331(ETNPPL)
MBEZ129562193(ETNPPL)
SSC100519324(ETNPPL)
CFR102512127(ETNPPL)
CBAI105067947(ETNPPL)
CDK105089893(ETNPPL)
VPC102540016(ETNPPL)
BACU102998195(ETNPPL)
LVE103090736(ETNPPL)
OOR101286361(ETNPPL)
DLE111171494(ETNPPL)
PCAD102979831(ETNPPL)
PSIU116754640(ETNPPL)
NASI112397686(ETNPPL)
ECB100072903(ETNPPL)
EPZ103554830(ETNPPL)
EAI106829807(ETNPPL)
MYB102253899(ETNPPL)
MYD102756358(ETNPPL)
MMYO118673107(ETNPPL)
MLF102427791(ETNPPL)
MNA107534375(ETNPPL)
PKL118702866(ETNPPL)
EFUS103293877(ETNPPL)
HAI109379489(ETNPPL)
DRO112322364(ETNPPL)
SHON118977091(ETNPPL)
AJM119061443(ETNPPL)
PDIC114492421(ETNPPL)
PHAS123806818(ETNPPL)
MMF118640700(ETNPPL)
RFQ117022329(ETNPPL)
PPAM129085295(ETNPPL)
PALE102889096(ETNPPL)
PGIG120591146(ETNPPL)
PVP105293000(ETNPPL)
RAY107508831(ETNPPL)
MJV108397377(ETNPPL)
TOD119243638(ETNPPL)
SARA101549028(ETNPPL)
LAV100667590(ETNPPL)
TMU101346588
ETF101646887(ETNPPL)
DNM101425350(ETNPPL)
MDO100011201(ETNPPL)
GAS123251518(ETNPPL)
SHR100925382(ETNPPL)
AFZ127541355
PCW110218641(ETNPPL)
OAA100088896(ETNPPL)
GGA428743(ETNPPL)
PCOC116238005(ETNPPL)
MGP100542369(ETNPPL)
CJO107313266(ETNPPL)
TPAI128079989(ETNPPL)
LMUT125692576(ETNPPL)
NMEL110397367(ETNPPL)
APLA101793344(ETNPPL)
ACYG106038664(ETNPPL)
CATA118244579(ETNPPL)
AFUL116488711(ETNPPL)
TGU101234009(ETNPPL)
LSR110468000(ETNPPL)
SCAN103826006(ETNPPL)
PMOA120502714(ETNPPL)
OTC121348396(ETNPPL)
PRUF121360171(ETNPPL)
GFR102035271(ETNPPL)
FAB101820476(ETNPPL)
OMA130252147(ETNPPL)
PHI102110492(ETNPPL)
PMAJ107203221(ETNPPL)
CCAE111927770(ETNPPL)
CCW104697121(ETNPPL)
CBRC103617331(ETNPPL)
ETL114057915(ETNPPL)
ZAB102066776(ETNPPL)
ACHL103803819(ETNPPL)
SVG106854416(ETNPPL)
MMEA130576224(ETNPPL)
HRT120752607(ETNPPL)
FPG101911697(ETNPPL)
FCH102046282(ETNPPL)
CLV102093169(ETNPPL)
EGZ104135529(ETNPPL)
NNI104021163(ETNPPL)
PCRI104035415(ETNPPL)
PLET104619471(ETNPPL)
EHS104516750(ETNPPL)
PCAO104047600(ETNPPL)
ACUN113479672(ETNPPL)
TALA104359997(ETNPPL)
PADL103919541(ETNPPL)
AFOR103894236(ETNPPL)
ACHC115347653(ETNPPL)
HALD104310768(ETNPPL)
HLE104843347(ETNPPL)
AGEN126044963
GCL127015604
CCRI104168969(ETNPPL)
CSTI104553203(ETNPPL)
CMAC104479490(ETNPPL)
MUI104541722(ETNPPL)
BREG104633547(ETNPPL)
FGA104082650(ETNPPL)
GSTE104263193(ETNPPL)
LDI104339834
MNB103781236(ETNPPL)
OHA104327246(ETNPPL)
NNT104412787
SHAB115610715(ETNPPL)
DPUB104301794(ETNPPL)
PGUU104468276(ETNPPL)
ACAR104518405
CPEA104394490(ETNPPL)
AVIT104267937(ETNPPL)
CVF104286843(ETNPPL)
RTD128910423(ETNPPL)
CUCA104062861(ETNPPL)
TEO104372035(ETNPPL)
BRHI104501921(ETNPPL)
AAM106491893(ETNPPL)
AROW112972212(ETNPPL)
NPD112957314(ETNPPL)
TGT104578537(ETNPPL)
DNE112987876(ETNPPL)
SCAM104153472(ETNPPL)
ASN102369936(ETNPPL)
AMJ106736641(ETNPPL)
CPOO109309396(ETNPPL)
GGN109301065(ETNPPL)
PSS102456032(ETNPPL)
CMY102931281(ETNPPL)
CCAY125635258(ETNPPL)
DCC119854995(ETNPPL)
CPIC101939791(ETNPPL)
TST117878078(ETNPPL)
CABI116837668(ETNPPL)
MRV120406734(ETNPPL)
ACS100564792(etnppl)
ASAO132776930(ETNPPL)
PVT110087286(ETNPPL)
SUND121930627(ETNPPL)
PBI103063776(ETNPPL)
PMUR107283097(ETNPPL)
CTIG120308256(ETNPPL)
TSR106537552(ETNPPL)
PGUT117679929(ETNPPL)
APRI131203263(ETNPPL)
PTEX113434793(ETNPPL)
NSS113412828(ETNPPL)
VKO123022807(ETNPPL)
PMUA114604288(ETNPPL)
PRAF128421274(ETNPPL)
ZVI118083994(ETNPPL)
HCG128327697(ETNPPL)
GJA107123225(ETNPPL)
STOW125440137(ETNPPL)
EMC129337047(ETNPPL)
XLA108706698 446472(etnppl.L)
XTR100124921(etnppl)
NPR108798298(ETNPPL)
RTEM120917861(ETNPPL)
BBUF120989927(ETNPPL)
BGAR122943868(ETNPPL)
MUO115461174(ETNPPL)
GSH117365649(ETNPPL)
DRE393421(etnppl)
SRX107758277(etnppl)
SANH107702209(etnppl)
SGH107578034
CAUA113074289(etnppl)
PTET122349278
LROH127168854(etnppl)
OMC131543605(etnppl)
PPRM120477654(etnppl)
RKG130077183(etnppl)
MAMB125261331(etnppl)
CIDE127516503
MASI127445069 127455677
TROS130559620(etnppl)
TDW130418305(etnppl)
MANU129449646(etnppl)
IPU108267613
IFU128609975(etnppl)
PHYP113540638(etnppl)
SMEO124388112(etnppl)
TFD125138334(etnppl)
TVC132848552(etnppl)
AMEX103024688(etnppl)
CMAO118826549(etnppl)
EEE113577314(etnppl)
CHAR105904746(etnppl)
TRU101064182(etnppl)
TFS130522077(etnppl)
TNGGSTEN00034857G001
LCO104937523(etnppl)
NCC104966106(etnppl)
TBEN117487952(etnppl)
CGOB115023753(etnppl)
PGEO117463381(etnppl)
GACU117553743(etnppl)
ELY117272760(etnppl)
EFO125883555(etnppl)
PLEP121962060(etnppl)
SLUC116039905(etnppl)
ECRA117934714(etnppl)
ESP116686035(etnppl)
PFLV114545826(etnppl)
GAT120821495(etnppl)
PPUG119222705(etnppl)
AFB129093193(etnppl)
CLUM117747989(etnppl)
MSAM119912513(etnppl)
SCHU122869674(etnppl)
CUD121504649(etnppl)
ALAT119027061(etnppl)
MZE101472558(etnppl)
ONL100692124(etnppl)
OAU116332908(etnppl)
OLA101168404(etnppl)
OML112156261(etnppl)
XMA102219957(etnppl)
XCO114157432(etnppl)
XHE116732907(etnppl)
PRET103480702(etnppl)
PFOR103143400(etnppl)
PLAI106946570(etnppl)
PMEI106929286(etnppl)
GAF122820618(etnppl)
PPRL129373276(etnppl)
CVG107086392(etnppl)
CTUL119776120(etnppl)
GMU124880264(etnppl)
NFU107377083(etnppl)
KMR108234824(etnppl)
ALIM106514874(etnppl)
NWH119416692(etnppl)
AOCE111589165(etnppl)
MCEP125005157(etnppl)
CSEM103390449(etnppl)
POV109634766(etnppl)
SSEN122766744(etnppl)
HHIP117752255(etnppl)
HSP118102449(etnppl)
LCF108892860
SDU111231620(etnppl)
SLAL111649906(etnppl)
XGL120797698(etnppl)
HCQ109507021(etnppl)
SSCV125978207
SBIA133494637(etnppl)
PEE133397828(etnppl)
PTAO133472800(etnppl)
BPEC110159302(etnppl)
MALB109974270(etnppl)
BSPL114868468(etnppl)
SJO128384278(etnppl)
SASA106577459
STRU115194091
OTW112260124(etnppl)
OMY110531931(etnppl)
OGO124008245(etnppl)
ONE115138226(etnppl)
OKI109906635(etnppl)
OKE118368607(etnppl)
SALP111960266(etnppl)
SNH120030145(etnppl)
CCLU121554619(etnppl)
ELS105009072(etnppl)
SFM108927834(etnppl)
PKI111852760(etnppl)
AANG118227962(etnppl)
LOC102691132(etnppl)
PSPA121296472 121321715
ARUT117409331 117420588
PSEX120532282(etnppl)
LCM102358069(ETNPPL)
CMK103175786(etnppl)
RTP109911531
CPLA122552249
HOC132816102
LERI129699379
PMRN116940190
LRJ133350706
BFO118410862
BBEL109478260
CIN100184516
SCLV120338732
SPU588990
LPIC129281891
APLC110982125
AJC117112332
DMEDmel_CG8745(CG8745)
DER6545612
DSE6605607
DSIDsimw501_GD12648(Dsim_GD12648)
DYADyak_GE20050
DAN6501826
DSR110179541
DPO6901500
DPE6599171
DMN108158506
DWI6644187
DGR6569305
DMODmoj_GI21508
DAZ108619486
DNV115564759
DHE111594891
DVI6632193
CCAT101453086
BOD106615905
BDR105229745
RZE108363633 108376654
TDA119670965
MDE101888323 101890114
SCAC106092798
LSQ119608100
GFS119644653
ECOE129944331
CLON129605306
HIS119657200
AGA1271947
ACOZ120961520
AARA120906308
AMER121598345
ASTE118504119
AFUN125774938
AMOU128307074
AALI118458142
AAG5576312
AALB109421834 109422780 115253777
CQUCpipJ_CPIJ006409
CPII120426460 120430556
CNS116344808
BCOO119067531
AME408817
ACER108000000
ALAB122712522
ADR102672982
AFLR100871917
BIM100747062
BBIF117207365
BVK117231929
BVAN117162712
BTER100650318
BAFF126914585
BPYO122566530
BPAS132910097
FVI122532833
CCAL108625872
OBB114872478
MGEN117226587
CGIG122396373
SOC105205780
MPHA105835917
AEC105150490
ACEP105625926
PBAR105425367
VEM105568181
HST105181725
DQU106741190
CFO105254428
FEX115243030
LHU105671956
PGC109859879
OBO105281321
PCF106787455
PFUC122522253
VPS122634580
VCRB124430161
NVI100122119
CSOL105364073
TPRE106650800
LHT122498062
LBD127287729
MDL103578841
CGLO123259643
FAS105268103
DAM107041615
AGIF122854812
CINS118064953
VCAN122409153
CCIN107270185
DSM124408278
NLO107225157
TCA656564
DPA109538509
SOY115891596
AGRG126743320
ATD109597022
CSET123315279
AGB108906364
LDC111514524
NVL108566258
APLN108732811
PPYR116163427
OTU111420681
BMOR101743589
BMAN114240794
MSEX115445609
DPLKGM_208998
BANY112042859
MJU123867820
NIQ126768947
VCD124532379
MCIX123654975
PMAC106720379
PPOT106103763
PXU106120923
PRAP110994575
PBX123711257
PNAP125053223
ZCE119840342
CCRC123693127
LSIN126967183
HAW110374579
HZE124631793
TNL113500448
SLIU111355594
OFU114363810
PXY105381966 105384463
PGW126369872
CFEL113386779
CCRN123297605
API100165269
DNX107166959
AGS114128260
RMD113549128
ACOO126838411
DVT126900567
BTAB109036494 109042296
DCI103515527
CLEC106664015
HHAL106687656
NLU111048974
HVI124359196
MQU128983218 128988939
PHUPhum_PHUM285460
FOC113211699
TPAL117647668
ZNE110838756
CSEC111871059
SGRE126284717
IEL124160165 124171745
FCD110851792
DPXDAPPUDRAFT_202337 DAPPUDRAFT_209533 DAPPUDRAFT_308321
DMK116928742 116932377
DPZ124311164 124349289
PVM113804714 113814898 113818469 113819760
PJA122242355 122250058 122255254
PCHN125033168 125036715 125041671
PMOO119578046 119581877 119592764
HAME121856856 121861468 121879078
PCLA123754015 123773250 123773411
CQD128694447 128696280
PTRU123505038 123519899
ESN126981316 126981855
HAZT108669541 108676322 108678888
EAF111703083 111711729
LSM121127723
TCF131883262 131886515 131887154 131892042
PPOI119092169 119096876 119103429 119104463 119104497 119104720
ISC8030734
DSV119437644
RSAN119376410 119379596
RMP119161932
VDE111244905
VJA111258573 111271131
TUT107370862
DPTE113790755
DFR124496671
CSCU111640055
PTEP107456533
UDV129227043
SDM118203968
LPOL106457289 106458945
PMEO129584951
CELCELE_T01B11.2(eppl-1)
CBRCBG_18478
CRQGCK72_015367
NAINECAME_07923
HROHELRODRAFT_108850
LGILOTGIDRAFT_210543 LOTGIDRAFT_81966
PVUL126810760 126812449
PCAN112561769 112561781 112568944
BGT106054843
GAE121379266
HRF124131667 124142291
HRJ124280916 124291740
CRG105333580 105341701
CVN111120839 111122045 111122410
CANU128166296 128167404
OED125668452 125669791
MYI110447364 110451507
PMAX117323135 117328553
MCAF127708683 127708689
MMER123563106 123564829
RPHI132726698 132753430
DPOL127866062 127868153
OBI106873832
OSN115213940
LAK106151457 106153187
NVE5512740
EPA110238800
ATEN116291063
ADF107356041
AMIL114955058
PDAM113664984
SPIS111329396
DGT114537750 114537751 114537944
XEN124453467
HMG100207719
TADTRIADDRAFT_33925
AQU100633968 100636649
CRECHLRE_16g650650v5
VCNVOLCADRAFT_92827
MNGMNEG_5549
CSLCOCSUDRAFT_36628
CVRCHLNCDRAFT_19399
APROF751_2216
MBRMONBRDRAFT_30473
SREPTSG_00900
PTIPHATR_52110
FCYFRACYDRAFT_275149
TPSTHAPSDRAFT_2775
EHXEMIHUDRAFT_416568 EMIHUDRAFT_457990
NGRNAEGRDRAFT_1387
THINCRN91_00395
DODDCS32_11705
LACICW733_14395
MLTVC82_1162
MUREQY75_05865
 » show all
Reference
1  [PMID:5498429]
  Authors
Fleshood HL, Pitot HC.
  Title
The metabolism of O-phosphorylethanolamine in animal tissues. I. O-phosphorylethanolamine phospho-lyase: partial purification and characterization.
  Journal
J Biol Chem 245:4414-20 (1970)
Reference
2  [PMID:4357716]
  Authors
Jones A, Faulkner A, Turner JM.
  Title
Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1-aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and amino alcohol o-phosphate phospho-lyase in aldehyde formation.
  Journal
Biochem J 134:959-68 (1973)
DOI:10.1042/bj1340959
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.2
IUBMB Enzyme Nomenclature: 4.2.3.2
ExPASy - ENZYME nomenclature database: 4.2.3.2
BRENDA, the Enzyme Database: 4.2.3.2
CAS: 37290-88-3

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