KEGG   ENZYME: 4.2.3.206
Entry
EC 4.2.3.206                Enzyme                                 
Name
(-)-cyatha-3,12-diene synthase;
eriG (gene name);
CyaTC
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranylgeranyl diphosphate-lyase [(-)-cyatha-3,12-diene-forming]
Reaction(IUBMB)
geranylgeranyl diphosphate = (-)-cyatha-3,12-diene + diphosphate [RN:R13099]
Reaction(KEGG)
R13099
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
(-)-cyatha-3,12-diene [CPD:C22612];
diphosphate [CPD:C00013]
Comment
The enzyme, characterized from the fungi Hericium erinaceus and Cyathus africanus, requires Mg2+ for activity.
History
EC 4.2.3.206 created 2022
Orthology
K26350  (-)-cyatha-3,12-diene synthase
Reference
1  [PMID:28371074]
  Authors
Yang YL, Zhang S, Ma K, Xu Y, Tao Q, Chen Y, Chen J, Guo S, Ren J, Wang W, Tao Y, Yin WB, Liu H.
  Title
Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi.
  Journal
Angew Chem Int Ed Engl 56:4749-4752 (2017)
DOI:10.1002/anie.201700565
  Sequence
[ag:ARE72244 ARE72248]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.206
IUBMB Enzyme Nomenclature: 4.2.3.206
ExPASy - ENZYME nomenclature database: 4.2.3.206
BRENDA, the Enzyme Database: 4.2.3.206

  All links  
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (2)   

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