KEGG   ENZYME: 4.2.3.218
Entry
EC 4.2.3.218                Enzyme                                 
Name
variediene synthase;
EvVS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, variediene-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate = variediene + diphosphate [RN:R13234]
Reaction(KEGG)
R13234
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
variediene [CPD:C22844];
diphosphate [CPD:C00013]
Comment
A diterpenoid synthase enzyme isolated from the fungus Aspergillus stellatus.
History
EC 4.2.3.218 created 2023
Orthology
K27205  variediene synthase
Reference
1  [PMID:26546087]
  Authors
Qin B, Matsuda Y, Mori T, Okada M, Quan Z, Mitsuhashi T, Wakimoto T, Abe I.
  Title
An Unusual Chimeric Diterpene Synthase from Emericella variecolor and Its Functional Conversion into a Sesterterpene Synthase by Domain Swapping.
  Journal
Angew Chem Int Ed Engl 55:1658-61 (2016)
DOI:10.1002/anie.201509263
  Sequence
[ag:BAT32888]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.218
IUBMB Enzyme Nomenclature: 4.2.3.218
ExPASy - ENZYME nomenclature database: 4.2.3.218
BRENDA, the Enzyme Database: 4.2.3.218

  All links  
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (2)   

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