KEGG   ENZYME: 4.2.3.224
Entry
EC 4.2.3.224                Enzyme                                 
Name
allokutznerene synthase;
PmS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, allokutznerene-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate = allokutznerene + diphosphate [RN:R13296]
Reaction(KEGG)
R13296
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
allokutznerene [CPD:C22898];
diphosphate [CPD:C00013]
Comment
A diterpene synthase isolated from the bacterium Allokutzneria albata. It also produces phomopsene (EC 4.2.3.222, phomopsene synthase) and traces of (-)-spiroviolene (EC 4.2.3.158, (-)-spiroviolene synthase).
History
EC 4.2.3.224 created 2024
Reference
1  [PMID:29758116]
  Authors
Lauterbach L, Rinkel J, Dickschat JS.
  Title
Two Bacterial Diterpene Synthases from Allokutzneria albata Produce Bonnadiene, Phomopsene, and Allokutznerene.
  Journal
Angew Chem Int Ed Engl 57:8280-8283 (2018)
DOI:10.1002/anie.201803800
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.224
IUBMB Enzyme Nomenclature: 4.2.3.224
ExPASy - ENZYME nomenclature database: 4.2.3.224
BRENDA, the Enzyme Database: 4.2.3.224

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