KEGG   ENZYME: 4.2.3.25
Entry
EC 4.2.3.25                 Enzyme                                 
Name
S-linalool synthase;
LIS;
Lis;
3S-linalool synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming]
Reaction(IUBMB)
geranyl diphosphate + H2O = (3S)-linalool + diphosphate [RN:R07631]
Reaction(KEGG)
R07631
Substrate
geranyl diphosphate [CPD:C00341];
H2O [CPD:C00001]
Product
(3S)-linalool [CPD:C11389];
diphosphate [CPD:C00013]
Comment
Requires Mn2+ or Mg2+ for activity. Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the enzyme from the flower Clarkia breweri [1]. Unlike many other monoterpene synthases, only a single product, (3S)-linalool, is formed.
History
EC 4.2.3.25 created 2006
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15086  (3S)-linalool synthase
K22049  S-linalool synthase
Genes
ATHAT1G61680(TPS14)
CSAT104705165
BNA106393947
BOE106314371
THJ104809528 104818931 104818943
CSV101204552
RCU8267425
VVI100244313 100852527
OSA4328124
DOSAOs02t0121700-01(Os02g0121700)
BDI100823591
ATS109736851
TDC119314480 119315591 119315592 119318901 119320186 119320773 119320774 119320901 119321507 119321735 119321939 119322945 119324776 119325690 119326303 119342952 119344547 119352067 119365784
TAES123039445 123054688 123130192 123130193 123130194 123130195 123130196 123133528 123133529 123133531 123133532 123133533 123135858 123138836 123138838 123138839 123138844 123138847 123138848 123139433 123140864 123140976 123140978 123140979 123140980 123140983 123140984 123170376 123186200
TUA125515763 125516239 125516497 125517417 125529189 125530472
SBI8085232 8085234
ZMA103654934 732758
SITA101779235
SVS117837512 117844560 117862933
PVIR120704116 120704456 120704531 120704606
PHAI112877004 112877011
 » show all
Reference
1  [PMID:7864636]
  Authors
Pichersky E, Lewinsohn E, Croteau R.
  Title
Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri.
  Journal
Arch Biochem Biophys 316:803-7 (1995)
DOI:10.1006/abbi.1995.1107
Reference
2  [PMID:11532177]
  Authors
Lucker J, Bouwmeester HJ, Schwab W, Blaas J, van der Plas LH, Verhoeven HA.
  Title
Expression of Clarkia S-linalool synthase in transgenic petunia plants results in the accumulation of S-linalyl-beta-D-glucopyranoside.
  Journal
Plant J 27:315-24 (2001)
DOI:10.1046/j.1365-313x.2001.01097.x
Reference
3  [PMID:8768373]
  Authors
Dudareva N, Cseke L, Blanc VM, Pichersky E
  Title
Evolution of floral scent in Clarkia: novel patterns of S-linalool synthase gene expression in the C. breweri flower.
  Journal
Plant Cell 8:1137-48 (1996)
DOI:10.1105/tpc.8.7.1137
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.25
IUBMB Enzyme Nomenclature: 4.2.3.25
ExPASy - ENZYME nomenclature database: 4.2.3.25
BRENDA, the Enzyme Database: 4.2.3.25
CAS: 160477-81-6

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