KEGG   ENZYME: 4.2.3.43Help
Entry
EC 4.2.3.43                 Enzyme                                 

Name
fusicocca-2,10(14)-diene synthase;
fusicoccadiene synthase;
PaFS;
PaDC4
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranylgeranyl diphosphate-lyase (fusicocca-2,10(14)-diene-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate [RN:R09123]
Reaction(KEGG)
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
fusicocca-2,10(14)-diene [CPD:C18229];
diphosphate [CPD:C00013]
Comment
A multifunctional enzyme with EC 2.5.1.29 farnesyltranstransferase activity.
History
EC 4.2.3.43 created 2009
Pathway
ec00904  Diterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K14047  fusicocca-2,10(14)-diene synthase
Reference
1  [PMID:17360612]
  Authors
Toyomasu T, Tsukahara M, Kaneko A, Niida R, Mitsuhashi W, Dairi T, Kato N, Sassa T
  Title
Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi.
  Journal
Proc Natl Acad Sci U S A 104:3084-8 (2007)
DOI:10.1073/pnas.0608426104
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.43
IUBMB Enzyme Nomenclature: 4.2.3.43
ExPASy - ENZYME nomenclature database: 4.2.3.43
BRENDA, the Enzyme Database: 4.2.3.43

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