KEGG   ENZYME: 4.2.3.46
Entry
EC 4.2.3.46                 Enzyme                                 

Name
alpha-farnesene synthase;
(E,E)-alpha-farnesene synthase;
AFS1;
MdAFS1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate lyase [(3E,6E)-alpha-farnesene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate [RN:R08696]
Reaction(KEGG)
R08696
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(3E,6E)-alpha-farnesene [CPD:C09665];
diphosphate [CPD:C00013]
History
EC 4.2.3.46 created 2010
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K14173  alpha-farnesene synthase
Genes
CPAP: 110812202
CIT: 102618658 102625123
CIC: CICLE_v10014790mg CICLE_v10018045mg
TCC: 18597031
GRA: 105775103
GHI: 107925033 107941108
GAB: 108451362
DZI: 111275141 111278493 111278668 111318785
EGR: 104429922 104430427 104430515 104441154 104441155 104442740 104442741 104442742 104442748 104442750 104442752 104442754
GMX: 100805428(TPS27) 100812119(TPS21)
GSJ: 114374943
VRA: 106778111
VAR: 108339494
VUN: 114170633
CAM: 101497499
LJA: Lj3g3v3653420.2(Lj3g3v3653420.2)
LANG: 109353649
FVE: 101301453
MDM: 103446592
ZJU: 107421480
RCU: 8267421
JCU: 105650120
HBR: 110646158
POP: 7495294
PEU: 105107359
INI: 109167313
SIND: 105175393
LSV: 111897134
BVG: 104883054
 » show all
Reference
1  [PMID:14740213]
  Authors
Pechous SW, Whitaker BD
  Title
Cloning and functional expression of an ( E, E)-alpha-farnesene synthase cDNA from peel tissue of apple fruit.
  Journal
Planta 219:84-94 (2004)
DOI:10.1007/s00425-003-1191-4
  Sequence
[mdm:103446592]
Reference
2  [PMID:19181671]
  Authors
Green S, Squire CJ, Nieuwenhuizen NJ, Baker EN, Laing W
  Title
Defining the potassium binding region in an apple terpene synthase.
  Journal
J Biol Chem 284:8661-9 (2009)
DOI:10.1074/jbc.M807140200
  Sequence
[mdm:103446592]
Reference
3  [PMID:19516075]
  Authors
Nieuwenhuizen NJ, Wang MY, Matich AJ, Green SA, Chen X, Yauk YK, Beuning LL, Nagegowda DA, Dudareva N, Atkinson RG
  Title
Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa).
  Journal
J Exp Bot 60:3203-19 (2009)
DOI:10.1093/jxb/erp162
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.46
IUBMB Enzyme Nomenclature: 4.2.3.46
ExPASy - ENZYME nomenclature database: 4.2.3.46
BRENDA, the Enzyme Database: 4.2.3.46

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