KEGG   ENZYME: 4.2.3.49Help
Entry
EC 4.2.3.49                 Enzyme                                 

Name
(3R,6E)-nerolidol synthase;
terpene synthase 1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3R,6E)-nerolidol-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = (3R,6E)-nerolidol + diphosphate [RN:R09618]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
(3R,6E)-nerolidol [CPD:C19746];
diphosphate [CPD:C00013]
Comment
The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores [1]. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants.
History
EC 4.2.3.49 created 2010
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15793  acyclic sesquiterpene synthase
Genes
BDI: 100833760
SBI: 8072328
ZMA: 541974(tps1)
SITA: 101771563
Taxonomy
Reference
1  [PMID:12481088]
  Authors
Schnee C, Kollner TG, Gershenzon J, Degenhardt J
  Title
The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
  Journal
Plant Physiol 130:2049-60 (2002)
DOI:10.1104/pp.008326
  Sequence
[zma:541974]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.49
IUBMB Enzyme Nomenclature: 4.2.3.49
ExPASy - ENZYME nomenclature database: 4.2.3.49
BRENDA, the Enzyme Database: 4.2.3.49

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