KEGG   ENZYME: 4.2.3.57
Entry
EC 4.2.3.57                 Enzyme                                 
Name
(-)-beta-caryophyllene synthase;
beta-caryophyllene synthase;
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (caryophyllene-forming)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-beta-caryophyllene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (-)-beta-caryophyllene + diphosphate [RN:R08541]
Reaction(KEGG)
R08541
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(-)-beta-caryophyllene [CPD:C09629];
diphosphate [CPD:C00013]
Comment
Widely distributed in higher plants, cf. EC 4.2.3.89 (+)-beta-caryophyllene synthase.
History
EC 4.2.3.57 created 2011, modified 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K14184  alpha-humulene/beta-caryophyllene synthase
K15808  beta-caryophyllene synthase
Genes
ATHAT5G23960(TPS21)
CRB17882696 17886620
CSAT104706692
EUSEUTSA_v10012105mg EUTSA_v10012129mg
BRP103849526 103849591 103874257
BNA106352011 106380498
BOE106301560 106326551
RSZ108831150 108840558
THJ104818160 104818164 104818498
TWL119985452 119988733 120010736
TDC119345609
EGU105034997
MUS103992270
 » show all
Reference
1  [PMID:12409018]
  Authors
Cai Y, Jia JW, Crock J, Lin ZX, Chen XY, Croteau R
  Title
A cDNA clone for beta-caryophyllene synthase from Artemisia annua.
  Journal
Phytochemistry 61:523-9 (2002)
DOI:10.1016/S0031-9422(02)00265-0
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.57
IUBMB Enzyme Nomenclature: 4.2.3.57
ExPASy - ENZYME nomenclature database: 4.2.3.57
BRENDA, the Enzyme Database: 4.2.3.57
CAS: 110639-18-4

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