KEGG   ENZYME: 4.2.3.85Help
Entry
EC 4.2.3.85                 Enzyme                                 

Name
alpha-eudesmol synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-eudesmol-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = alpha-eudesmol + diphosphate [RN:R09788]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
alpha-eudesmol [CPD:C09663];
diphosphate [CPD:C00013]
Comment
The recombinant enzyme from ginger (Zingiber zerumbet) gives 62.6% beta-eudesmol, 16.8% 10-epi-gamma-eudesmol, 10% alpha-eudesmol, and 5.6% aristolene. cf. EC 4.2.3.68 (beta-eudesmol synthase) and EC 4.2.3.84 (10-epi-gamma-eudesmol synthase)
History
EC 4.2.3.85 created 2011
Orthology
K22055  beta/10-epi-gamma/alpha-eudesmol synthase
Reference
1  [PMID:18242187]
  Authors
Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R
  Title
Isolation and functional characterization of a beta-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith.
  Journal
FEBS Lett 582:565-72 (2008)
DOI:10.1016/j.febslet.2008.01.020
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.85
IUBMB Enzyme Nomenclature: 4.2.3.85
ExPASy - ENZYME nomenclature database: 4.2.3.85
BRENDA, the Enzyme Database: 4.2.3.85

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