KEGG   ENZYME: 4.3.1.2
Entry
EC 4.3.1.2                  Enzyme                                 
Name
methylaspartate ammonia-lyase;
beta-methylaspartase;
3-methylaspartase;
L-threo-3-methylaspartate ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
Sysname
L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)
Reaction(IUBMB)
L-threo-3-methylaspartate = mesaconate + NH3 [RN:R03696]
Reaction(KEGG)
R03696
Substrate
L-threo-3-methylaspartate [CPD:C03618]
Product
mesaconate [CPD:C01732];
NH3 [CPD:C00014]
Comment
A cobalamin protein.
History
EC 4.3.1.2 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04835  methylaspartate ammonia-lyase
Genes
AFM: AFUA_3G00790
NFI: NFIA_001410
AOR: AO090010000710
AFV: AFLA_014211
ACHE: ACHE_70014S
PDP: PDIP_33520
ECE: Z0892
ECS: ECs_0761
ECF: ECH74115_0829
ETW: ECSP_0779
ELX: CDCO157_0741
ECOO: ECRM13514_0750
ECOH: ECRM13516_0697
EOK: G2583_0892
ELR: ECO55CA74_04340
ECM: EcSMS35_0749
EUM: ECUMN_0814
ECT: ECIAI39_0701
EOC: CE10_0730
ELO: EC042_0753
EFE: EFER_2378
EMA: C1192_08695
ESZ: FEM44_18110
SES: SARI_02201
SDY: SDY_0673
SDZ: Asd1617_00848
ESH: C1N69_07900
EPU: QVH39_07900
KOX: KOX_14665
KOE: A225_1756
KOY: J415_22870
KOM: HR38_13440
KOK: KONIH1_08640
KOC: AB185_27495
KLL: BJF97_09010
KLW: DA718_19620
KGR: JJJ10_19550
KPAS: LUW96_15420
KLC: K7H21_19535
KLM: BWI76_08475
CKO: CKO_02419
CFD: CFNIH1_13770
CBRA: A6J81_09350
CWE: CO701_15165
CYO: CD187_16565
CPOT: FOB25_04015
CFQ: C2U38_07700
CSED: JY391_14750
CAMA: F384_03285
CAF: AL524_19000
CIF: AL515_08250
CFAR: CI104_08015
CIR: C2U53_17235
CIE: AN232_22705
CPAR: CUC49_03400
CTEL: GBC03_21985
CITZ: E4Z61_09960
CARS: E1B03_08815
CIX: M4I31_15970
CIB: HF677_016175
CENS: P2W74_15920
ESC: Entcl_1732
KLE: AO703_13285
BUF: D8682_20785
BFT: MNO13_05010
BSEL: RHD99_04810
YRE: HEC60_20895
PVJ: LMA04_06040
YEN: YE4043
YEP: YE105_C3763
YEY: Y11_31521
YEW: CH47_3688
YET: CH48_1495
YEF: FORC2_0151
YEE: YE5303_38771
YAL: AT01_1098
YIN: CH53_313
YRO: CH64_1340
YHI: D5F51_21360
YEL: LC20_00182
YCA: F0T03_21045
YAS: N0H69_09490
MMK: MU9_1023
HAV: AT03_08650
OPO: DSM2777_13860
PPUL: RO07_15990
BPE: BP0806 BP3177
BPC: BPTD_0804 BPTD_3139
BPER: BN118_0709
BPET: B1917_0643 B1917_2973
BPEU: Q425_31590 Q425_7420
BPAR: BN117_3385 BN117_3938
BPA: BPP3422 BPP3864
BBH: BN112_4085 BN112_4543
BBR: BB3872 BB4337
BBM: BN115_3544 BN115_4013
BBX: BBS798_3652 BBS798_4114
BFZ: BAU07_20575
BOH: AKI39_19475
BGM: CAL15_20690
XYK: GT347_12540
MLO: mlr6095
MLN: A9174_31760
MCI: Mesci_5690
MCIC: A4R28_21445
MOP: Mesop_6269
MAM: Mesau_05741
MAMO: A6B35_31635 A6B35_31710
MESW: A9K65_030880
MESM: EJ066_12585
MJR: EB229_32430
MERD: EB233_30065
MMEI: LRP31_10480
RSUL: N2599_36735
BIC: LMTR13_26000
PPAN: ESD82_15275
GFU: KM031_18930
ALH: G6N82_05195
ELQ: Ga0102493_112996
CTC: CTC_02563
CTET: BN906_02814
CLJ: CLJU_c40610
CAH: CAETHG_1904
CSQ: CSCA_4328
CACE: CACET_c34410
CCK: Ccar_17555 Ccar_19615
CEU: A7L45_08020
CFM: BJL90_02575
CARG: RSJ17_03855
CDRK: B9W14_23400
CCOH: SAMEA4530647_2259
CLOS: DMR38_20135
CCAA: KQH81_15280
CTAG: LL095_20705
HHW: NCTC503_02397
CALE: FDN13_04640
OCW: OW730_04540
PROQ: P6M73_02460
PETR: QKW49_11540
DSY: DSY3233
DHD: Dhaf_4400
DDH: Desde_3779
DMT: DESME_13810
DOR: Desor_5275
DAI: Desaci_4373
DMI: Desmer_4259
DCA: Desca_0604
DRM: Dred_2689
DRU: Desru_0927
DFG: B0537_13815
FWA: DCMF_09590
AACX: DEACI_0128
ACAE: HYG86_02375
CTHM: CFE_0619
FMS: M1R53_04075
PROM: QO263_09920
EUU: ADJ67_05945
BYL: A4V09_10270
BHAN: CGC63_11295
BPRO: PMF13cell1_03217
BLAR: LC508_07905
BCOC: BLCOC_23090
VGU: HYG85_02135
VPY: HZI73_09950
AMT: Amet_3414
TEM: JW646_17970
TGC: L0P85_10055
TMY: TEMA_08780
TPET: TPHSE_23060
PBQ: C3V37_01025
EAC: EAL2_808p05890
CHY: CHY_0484 CHY_0582
TPZ: Tph_c20250
TEP: TepRe1_0115
TAE: TepiRe1_0120
HOR: Hore_15430
HPK: Hprae_1850
HALS: D7D81_15595
IFN: GM661_12735
AAR: Acear_0480
HHL: Halha_1649
AFT: BBF96_08380
TIS: P3962_02615
ECOU: M1R54_02150
PUF: UFO1_3073
PFT: JBW_01516
MANA: MAMMFC1_00632
STED: SPTER_10690
MANR: MPAN_001680
MBJ: KQ51_00879
XCL: G4Z02_00740
TBK: HF295_06620
TBM: BK010_00845
TBZ: BK011_00735
MSED: E3O41_00265
FRP: AX769_17710
NMES: H9L09_01760
MHAI: OHB01_26590
MMAR: MODMU_4014
MOM: KUM42_03575
KAL: KALB_5717
MTUA: CSH63_31865
BSOL: FSW04_00285
BALA: DSM104299_03890
ABAO: BEQ56_05600
MTAR: DF168_01552
TDE: TDE_2235
TPI: TREPR_1304
TPED: TPE_1176
TPK: JO40_01075
SCD: Spica_1659
FVA: FV113G1_25160
FUL: C4N20_01145
FMO: C4N19_13190
FHO: H9Q81_10155
IPO: Ilyop_0556
CSOM: MKD34_06450
CPOR: BED41_14050
PAH: Poras_1170
PCRE: NCTC12858_01580
PSOE: CE91St14_10350
PET: PEIBARAKI_4288
PROJ: KDN43_05785
TOH: BCB71_00035
PIT: PIN17_0467
PNI: J5A59_01360
DTH: DICTH_1229
DTU: Dtur_1344
HAL: VNG_2289G(mal)
HSL: OE_4207F(mal)
HANR: LJ422_09240
HAGS: JT689_10590
HABO: JRZ79_08965
HALX: M0R89_18080
HAXY: NGM07_04610
SALI: L593_04670
HMA: rrnAC0687(mal)
HHI: HAH_1339(mal)
HHN: HISP_06855
HAB: SG26_14700
HTA: BVU17_06525
HALJ: G9465_08575
HSIN: KDQ40_06775
HMU: Hmuk_2982
HALZ: E5139_02185
HALL: LC1Hm_2319(mal)
HAZP: GBQ70_02185
HRR: HZS55_19995
HPEL: HZS54_23495
HGI: ABY42_16395
HTU: Htur_1592
HSAL: JMJ58_00675
HAKZ: J0X25_14770
NMG: Nmag_3336(mal)
HXA: Halxa_3157
NAT: NJ7G_3291
NPE: Natpe_2592
NVR: FEJ81_11890
NPL: FGF80_10930
NAY: HYG81_14700
HALY: HYG82_17320
HJT: DVR14_02945
HLO: J0X27_02305
NGE: Natgr_2182 Natgr_3386
HRU: Halru_1550
SAWL: NGM29_08780
HALV: NGM15_00945
NOU: Natoc_1511
HLR: HALLA_00800 HALLA_10845
HLC: CHINAEXTREME16085
NAJ: B1756_12015
NAG: AArcMg_1647
NAN: AArc1_1992
NARA: QQ977_05690
NBG: DV706_12990
NAS: GCU68_13735
HDA: BB347_04020
 » show all
Reference
1  [PMID:13618029]
  Authors
BARKER HA, SMYTH RD, WAWSZKIEWICZ EJ, LEE MN, WILSON RM.
  Title
Enzymic preparation and characterization of an alpha-L-beta-methylaspartic acid.
  Journal
Arch Biochem Biophys 78:468-76 (1958)
DOI:10.1016/0003-9861(58)90371-0
Reference
2
  Authors
Bright HJ, Ingraham LL.
  Title
The preparation of crystalline beta-methylaspartase.
  Journal
Biochim Biophys Acta 44:586-588 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.2
IUBMB Enzyme Nomenclature: 4.3.1.2
ExPASy - ENZYME nomenclature database: 4.3.1.2
BRENDA, the Enzyme Database: 4.3.1.2
CAS: 9033-26-5

  All links  
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1403)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (292)   
   KEGG MGENES (986)   
   RefGene (124)   
Protein sequence (3571)   
   UniProt (1432)   
   SWISS-PROT (5)   
   RefSeq(pep) (2122)   
   PDBSTR (12)   
DNA sequence (21873)   
   RefSeq(nuc) (17200)   
   GenBank (2384)   
   EMBL (2289)   
3D Structure (6)   
   PDB (6)   
Protein domain (7)   
   InterPro (5)   
   Pfam (2)   
All databases (26874)   

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