KEGG   ENZYME: 4.3.1.31Help
Entry
EC 4.3.1.31                 Enzyme                                 

Name
L-tryptophan ammonia lyase;
WAL
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
L-tryptophan ammonia-lyase (3-indoleacrylate-forming)
Reaction(IUBMB)
L-tryptophan = 3-indoleacrylate + NH3 [RN:R11328]
Reaction(KEGG)
Substrate
L-tryptophan [CPD:C00078]
Product
3-indoleacrylate [CPD:C21283];
NH3 [CPD:C00014]
Comment
The enzyme, characterized from the bacterium Rubrivivax benzoatilyticus JA2, requires no cofactors. It acts on L-phenylalanine and L-glutamate with about 60% of the activity with L-tryptophan, and on L-tyrosine, glycine, and L-alanine with about 30% of the activity.
History
EC 4.3.1.31 created 2016
Reference
1  [PMID:25961404]
  Authors
Kumavath RN, Ramana ChV, Sasikala Ch, Barh D, Kumar AP, Azevedo V
  Title
Isolation and Characterization of L-Tryptophan Ammonia Lyase from Rubrivivax benzoatilyticus Strain JA2.
  Journal
Curr Protein Pept Sci 16:775-81 (2015)
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.31
IUBMB Enzyme Nomenclature: 4.3.1.31
ExPASy - ENZYME nomenclature database: 4.3.1.31
BRENDA, the Enzyme Database: 4.3.1.31

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