KEGG   ENZYME: 4.3.3.4
Entry
EC 4.3.3.4                  Enzyme                                 
Name
deacetylipecoside synthase;
deacetylipecoside dopamine-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Amine-lyases
Sysname
deacetylipecoside dopamine-lyase (secologanin-forming)
Reaction(IUBMB)
deacetylipecoside + H2O = dopamine + secologanin [RN:R05749]
Reaction(KEGG)
R05749
Substrate
deacetylipecoside [CPD:C07307];
H2O [CPD:C00001]
Product
dopamine [CPD:C03758];
secologanin [CPD:C01852]
Comment
The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC 4.3.3.3 deacetylisoipecoside synthase. The product is rapidly converted to demethylalangiside.
History
EC 4.3.3.4 created 2000
Pathway
ec00950  Isoquinoline alkaloid biosynthesis
Reference
1
  Authors
DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H.
  Title
Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii.
  Journal
Phytochemistry 45:477-484 (1997)
Other DBs
ExplorEnz - The Enzyme Database: 4.3.3.4
IUBMB Enzyme Nomenclature: 4.3.3.4
ExPASy - ENZYME nomenclature database: 4.3.3.4
BRENDA, the Enzyme Database: 4.3.3.4
CAS: 192827-93-3

  All links  
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
All databases (9)   

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