KEGG   ENZYME: 4.4.1.14
Entry
EC 4.4.1.14                 Enzyme                                 
Name
1-aminocyclopropane-1-carboxylate synthase;
1-aminocyclopropanecarboxylate synthase;
1-aminocyclopropane-1-carboxylic acid synthase;
1-aminocyclopropane-1-carboxylate synthetase;
aminocyclopropanecarboxylic acid synthase;
aminocyclopropanecarboxylate synthase;
ACC synthase;
S-adenosyl-L-methionine methylthioadenosine-lyase;
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)
Class
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
Sysname
S-adenosyl-L-methionine S-methyl-5'-thioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)
Reaction(IUBMB)
S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine [RN:R00179]
Reaction(KEGG)
R00179
Substrate
S-adenosyl-L-methionine [CPD:C00019]
Product
1-aminocyclopropane-1-carboxylate [CPD:C01234];
S-methyl-5'-thioadenosine [CPD:C00170]
Comment
A pyridoxal 5'-phosphate protein. The enzyme catalyses an alpha,gamma-elimination.
History
EC 4.4.1.14 created 1984, modified 2021
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01762  1-aminocyclopropane-1-carboxylate synthase
K20772  1-aminocyclopropane-1-carboxylate synthase 1/2/6
Genes
SDM118199925
OSN118768601
ATHAT1G01480(ACS2) AT2G22810(ACS4) AT3G49700(ACS9) AT3G61510(ACS1) AT4G08040(ACS11) AT4G11280(ACS6) AT4G26200(ACS7) AT4G37770(ACS8) AT5G65800(ACS5)
ALY9301057 9303005 9305694 9308639 9310585 9312060 9314454 9314705 9325428
CRB17875111 17878182 17880867 17881710 17883512 17886384 17886694 17889661 17898028
CSAT104699746 104699855 104707149 104707428 104711491 104716344 104717627 104718982 104722199 104722336 104727242 104729387 104730789 104737125 104737126 104738269 104738648 104744258 104749193 104754295 104758959 104762767 104780793 104788442 104791197
EUSEUTSA_v10000582mg EUTSA_v10004145mg EUTSA_v10005927mg EUTSA_v10007457mg EUTSA_v10011085mg EUTSA_v10027155mg EUTSA_v10027427mg EUTSA_v10028605mg EUTSA_v10029359mg
BRP103833884 103835047 103837595 103841975 103844651 103855315 103857842 103858466 103860626 103861616 103864396 103865940 103873033 103874018
BNA106351310 106351622 106351946 106357963 106359937 106360328 106368473 106370875 106385536 106385546 106394583 106395853 106396236 106397217 106399918 106407459 106409122 106414306 106414853 106415781 106422378 106426257 106426788 106426806 106431216 106432488 106432491 106444821 106445177 106449687 106449806 111204708 111214175 111214679
BOE106292450 106293242 106299018 106301527 106304473 106310902 106310923 106316789 106319341 106325916 106332403 106332625 106333209 106340279
RSZ108810287 108811567 108826348 108827978 108828192 108830480 108834828 108840732 108841986 108841991 108844731 108852117 108852226 108852663 108860374 108860375 108861750 108861871 108862661
THJ104798348 104811738 104814722 104817315 104819275 104824936 104825800 104825862 104827602
CPAP110809089 110810587 110811354 110815304 110819154
CIT102611477 102612741 102614629 102614668 102621630
CICCICLE_v10003248mg CICLE_v10010572mg CICLE_v10019920mg CICLE_v10019970mg CICLE_v10027248mg
PVY116105149 116107530 116110313 116133680 116141384
MINC123193661 123193821 123195312 123199743 123204748 123206204 123206888 123207827 123211268 123216302 123216851 123222742
TCC18588438 18591920 18606590 18611347 18614078
GRA105763853 105765261 105766030 105767540 105767610 105777048 105788281 105789777 105791126 105791392 105801920 105802246 105802741 105804075
GHI107897109 107899213 107902833 107903140 107904481 107905210 107911503 107915933 107917665 107923295 107923331 107932215 107935250 107938597 107945955 107947061 107947488 107949019 107949506 107950911 107952122 121217890 121220091 121222422 121223065 121223641 121229227 121231937
GAB108450653 108451870 108464961 108465156 108469142 108469270 108472553 108472862 108478912 108478985 108485771 108487597
DZI111284503 111289473 111292064 111292921 111300706 111304187 111304783 111310818 111313319 111313897 111315659 111316169
EGR104414047 104416907 104429768 104430670 104430671 104439025 104441716 104441717 104441718 104443409 104449230
GMX100037458(ACS) 100500423 100775969 100778925 100783062 100789346 100790271(ACS2) 100791024 100791928 100793020 100793912 100797692 100799562 100803507 100813347 100817401 547976(ACS1)
GSJ114367354 114375337 114375655 114390360 114393033 114395994 114407347 114408070 114412505 114413410 114413514 114414798 114417692 114419044 114421046 114422607 114424448
PVUPHAVU_002G008900g PHAVU_002G159800g PHAVU_002G293000g PHAVU_002G305000g PHAVU_003G232400g PHAVU_004G172300g PHAVU_008G058400g PHAVU_009G074800g PHAVU_010G103900g
VRA106756270 106759016 106760450 106766638 106767925 106769161 106773917 106777325 106777389
VAR108320353 108328137 108330524 108335566 108341300 108343970 108346272 108346573 108347299
VUN114162708 114167484 114173246 114173267 114178008 114179207 114179415 114179446 114184021
CCAJ109792173 109796318 109799512 109799665 109800648 109803088 109805792 109810552 109818867
APRC113850216 113854068 113855769 113859086 113862976 113866254 113867669 113869425 113869663
MTRMTR_3g103550 MTR_4g097540 MTR_5g015020 MTR_6g091760 MTR_7g079080 MTR_8g028600 MTR_8g098930 MTR_8g101750 MTR_8g101820
CAM101489267 101495414 101498086 101501111 101501866 101508051 101510660 101514377(ACS)
LJALj0g3v0243559.1(Lj0g3v0243559.1) Lj1g3v2766570.1(Lj1g3v2766570.1) Lj2g3v0909590.1(Lj2g3v0909590.1) Lj2g3v1982940.1(Lj2g3v1982940.1) Lj2g3v2051190.1(Lj2g3v2051190.1) Lj4g3v0706600.1(Lj4g3v0706600.1) Lj4g3v2990130.1(Lj4g3v2990130.1) Lj4g3v3017360.1(Lj4g3v3017360.1)
ADU107461133 107472766 107479619 107479870 107482547 107485807 107487560 107488156 107490118
AIP107607955 107617450 107628111 107630758 107634514 107638081 107641657 107644474
AHF112705087 112720599 112726355 112732346 112732600 112732856 112744203 112748160 112751325 112764004 112790692 112790850 112797527 112799681 112800461 112800765 112802033
LANG109330731 109330942 109332274 109337389 109349978 109349996 109351095 109356400 109358370 109359263
FVE101291920 101297773 101303587 101308797 101313158 105350288 105350769
RCN112173847 112180548 112182025 112189646 112189904 112189922
PPER18769044 18769052 18775476 18775762 18787058 18791560
PMUM103320507 103332068 103334841 103337567 103340764 103340765
PAVI110744374 110745926 110751100 110751120 110751761 110762457
PDUL117614605 117619189 117627994 117631761 117633661 117633662
MDM103400119 103405045 103406931 103408235 103411726 103415406 103428489 103430893 103439201 103443111 103450091 114821009
PXB103929658 103931408 103931583 103933174 103935793 103943957 103951619 103952690 103953381 103956316
ZJU107420607 107423985 107425000 107430205 107432928 107432945
MNT21390503 21391167 21396109 21406964 21409866
CSV101205326 101211475(CS-ACS1) 101212728(CS-ACS2) 101213522 101216963 101217331 116402703
CMO103484881 103488536(ACS11) 103492295(ACS-7) 103493143(CMe-ACS2) 103497687(CMe-ACS1)
BHJ120071750 120074437 120075316 120076491 120091810 120092851
MCHA111004776 111005492 111005744 111008139 111008407 111016173 111016473 111025659
CMAX111478535 111479912 111482963 111483220 111483239 111485190 111491962 111496971 111497071 111499253 111499264
CMOS111434077 111435906 111437574 111446996 111448029 111453796 111460262 111460306 111461528 111462752 111463483
CPEP111780669 111782101 111786147 111792971 111804369 111805837 111806625 111806626 111807362 111810417 111810625
RCU8265090 8265240 8267665 8286682 8287433
JCU105630798 105631005 105638336 105639890 105642929
HBR110633588 110635898 110638009 110638594 110656120 110657409 110664184 110664711 110667029 110669775 110672268 110673406
MESC110604211 110605770 110609805 110610310 110615063 110623138 110627552 110628831 110630477
POP18107686 7457358 7465553 7472629 7472745 7497311 7497612 7497805
PEU105107619 105111138 105117577 105120519 105124333 105124831 105129109 105130489
PALZ118028427 118031639 118033744 118037099 118048004 118056673 118057808 118063348
JRE108983882 108989033 108989760 108997341 108998101 109006403 109007326 109009229 109013607
QSU111986768 111997192 112007481 112010787 112035875
QLO115950708 115970076 115972430 115978352 115983881
TWL119980802 119983292 119987564 119995304 119997386 120004434 120009500 120013436
VVI100250639 100251690 100258512(ACS1) 100261151 100261943 100263876 100853374
VRI117907340 117915440 117919034 117925499 117931832 117932327
SLY101246650(LE-ACS1B) 101258054 101258353 101260914 101265900 101267421 112940919 543621(ACS7) 544028(ACS1A) 606300(ACS5) 606301(ACS8) 606302(ACS6) 606304(ACS2) 778292(ACS3) 778356(ACS4)
SPEN107006832 107007246 107007601 107010547 107010712 107010736 107014033 107017393 107018465 107025598 107027121 107027241 107027321
SOT102577574 102577619(STACS5) 102580821 102582615 102582710 102583042 102583502 102584590 102584912 102588307 102598934 102599253 102605100 102606459
SSTN125842385 125842388 125842393 125846358 125848507 125848582 125852505 125855503 125859844 125862892 125867071 125867074 125868397 125868399 125876731
CANN107839239 107841837 107844520 107845014 107861366 107864513 107864521 107869470
NTA107761132 107762799 107767058 107768881 107770971(ACCS2) 107771294 107771295 107772014(Acs7) 107773178 107776354 107778431(Acs8) 107785978 107787372 107791579 107792036(acs4) 107792558 107792559 107810571 107814996 107817443 107821040 107829216(acs2) 107829754 107831434(ACS1)
NSY104210634 104211860 104222299 104222407 104226114 104228033 104234875 104237480 104238493 104244092 104248383
NTO104087006 104087335 104088223 104112748 104115210 104115306 104115319 104116790 104117136 104119568 104120077
NAU109205644 109210465 109218840 109220219 109220530 109223202 109229811 109237500 109239471 109241083 109241084
INI109147706 109148244(ACS1) 109148245 109149201 109152762 109157165 109165764 109168460 109177530(ACS2) 109186234 109186722 109188612 109193908
ITR115999540 115999979 116000285 116012987 116013217 116014004 116014164 116023713 116027452 116027810 116030630 116032033
SIND105158273 105158571 105162012 105162155 105162216 105164055 105171944 105171945 105173022 105173819 105177851
OEU111365850 111367269 111374985 111380501 111383012 111385510 111390291 111390331 111398553 111407790
EGT105952698 105953451 105958911 105964048 105965418 105973667 105973822 105975860
SSPL121749286 121750705 121752722 121754871 121758032 121767164 121769895 121774046 121776474 121778735 121783914 121786483 121793774 121794072 121799936 121801136
HAN110864420 110865480 110883606 110895485 110897828 110909510 110911122 110911123 110922519 110922539 110922546 110936703 110936878 118489062
ECAD122578887 122579855 122589291 122593791 122596038 122597705 122602635 122603513
LSV111878569 111886468 111892562 111894665 111900308 111900984 111910693 111912966
CCAV112501623 112503173 112507458 112508951 112512610 112517266 112520827 112522365 112522408 112527503
DCR108195391 108198745 108205292 108206882 108211632 108214624 108226715
CSIN114261661 114261887 114275145 114278008 114279312 114284227 114307269 114307286 114312510 114313394 114316468
BVG104883947 104886974 104892244 104894995
SOE110778359 110779500 110788691 110803641 110805592 110805602
CQI110681722 110685603 110714439 110716696 110716943 110719582 110722600 110731584
NNU104591223 104600214 104600772 104604621 104609198 104613052
MING122070970 122072217 122072252 122082565 122082576 122082639 122085510
TSS122646222 122646404 122655644 122659875 122662309 122666060 122669755
PSOM113278032 113293988 113293991 113299227 113300486 113300521 113300612 113316306 113316308 113319170 113319212 113319394 113328949 113347971 113351239 113353425 113354097 113354154 113354155 113358382 113361394
NCOL116250006 116250847 116255951 116260317
OSA107275635 107275928 4327307 4333976 4336750
DOSAOs01t0192900-00(Os01g0192900) Os03t0727600-01(Os03g0727600) Os04t0578000-01(Os04g0578000) Os05t0196600-00(Os05g0196600) Os05t0319200-00(Os05g0319200)
OBR102701155 102701486 102709919 102716218 102720524
BDI100823860 100833332 100836412
ATS109742142 109756625 109766279 109774526
TDC119267206 119275063 119286804 119294913 119355993 119365129
TAES123046237 123057967 123064987 123074124 123082324 123094397 123099519 123189996 543237
TUA125532278 125547985 125553478
SBI8057616 8060541 8084354
ZMA100217270 100279981 103646045 107521951
SITA101753646 101756021 101758233 101759620
SVS117835029 117850503 117858251 117865806
PVIR120641527 120649903 120667556 120675147 120683464 120687243 120697656 120710430
PHAI112876230 112887357 112894523 112901520
PDA103699314 103704271 103707525 103709553
EGU105040474 105043325 105043536 105048002 105055886 105058291
MUS103969948 103973808 103976009(MA-ACS2) 103977650 103979532(MA-ACS4) 103980533 103982300 103982436 103982773 103984412 103985952(MA-ACS3)
DCT110096818 110099456 110101080 110101882 110104506 110106891 110112049
PEQ110019694 110029746 110030067 110030670 110038028 110038434
AOF109821268 109835287 109837839 109842938
ATR18424527 18428280 18443752 18445561
SMOSELMODRAFT_124697 SELMODRAFT_450990 SELMODRAFT_450992 SELMODRAFT_450993
PPP112280073
CRECHLRE_06g306400v5 CHLRE_06g306501v5
VCNVOLCADRAFT_120406
MNGMNEG_8138
CSLCOCSUDRAFT_57347
CVRCHLNCDRAFT_137035
OLUOSTLU_42674
OTAOT_ostta08g02660
MPPMICPUCDRAFT_16049
CMECYME_CMS398C
GSLGasu_16050
MAWMAC_04900
MAJMAA_09080
PLJVFPFJ_05984
BFUBCIN_04g01000
PSCOLY89DRAFT_637838 LY89DRAFT_733325
GLZGLAREA_13015
AORAO090103000336
ANGANI_1_628024(An02g04430)
PCSPc16g08030
ABEARB_02992
TVETRV_05130
PTEPTT_18741
NPAUCRNP2_3082
CNECNK02050
CNBCNBK1490
CNGCNAG_01865
TASAA1Q1_04002 A1Q1_04988
UMAUMAG_05676
PFPPFL1_01684
MLRMELLADRAFT_102000
MBRMONBRDRAFT_24686
SREPTSG_04007
DPPDICPUDRAFT_152148 DICPUDRAFT_25072
FCYFRACYDRAFT_178412
AAFAURANDRAFT_4027 AURANDRAFT_9697
SPARSPRG_03997
GTTGUITHDRAFT_84787
NGRNAEGRDRAFT_77215
TVATVAG_458460
SLDT261_7787
LMOIVV02_08020
KQIF1D05_11650
FSYFsymDg_0633
SENSACE_4299
SSYIEKG83_10730
SPDRG6053_17615 G6053_18345
EVIEchvi_4583
CPRVCYPRO_1870
 » show all
Reference
1  [PMID:24317737]
  Authors
Boller T, Herner RC, Kende H
  Title
Assay for and enzymatic formation of an ethylene precursor, 1-aminocyclopropane-1-carboxylic acid.
  Journal
Planta 145:293-303 (1979)
DOI:10.1007/BF00454455
Reference
2  [PMID:507845]
  Authors
Yu YB, Adams DO, Yang SF.
  Title
1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene biosynthesis.
  Journal
Arch Biochem Biophys 198:280-6 (1979)
DOI:10.1016/0003-9861(79)90420-X
Other DBs
ExplorEnz - The Enzyme Database: 4.4.1.14
IUBMB Enzyme Nomenclature: 4.4.1.14
ExPASy - ENZYME nomenclature database: 4.4.1.14
BRENDA, the Enzyme Database: 4.4.1.14
CAS: 72506-68-4

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