KEGG   ENZYME: 4.99.1.2
Entry
EC 4.99.1.2                 Enzyme                                 
Name
alkylmercury lyase;
organomercury lyase;
organomercurial lyase;
alkylmercury mercuric-lyase
Class
Lyases;
Other lyases;
Sole sub-subclass for lyases that do not belong in the other subclasses
Sysname
alkylmercury mercury(II)-lyase (alkane-forming)
Reaction(IUBMB)
an alkylmercury + H+ = an alkane + Hg2+ [RN:R03529]
Reaction(KEGG)
R03529 > R09339
Substrate
alkylmercury [CPD:C01343];
H+ [CPD:C00080]
Product
alkane [CPD:C01371];
Hg2+ [CPD:C00703]
Comment
Acts on CH3Hg+ and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.
History
EC 4.99.1.2 created 1978
Orthology
K00221  alkylmercury lyase
Genes
EUNpUMNK88_145(merB)
SEESNSL254_p_0164(merB)
EHMAB284_00875
KLLBJF97_30980
PAZOAYR47_00245
PUMHGP31_24370(merB) HGP31_25850(merB)
PTZHU718_021355(merB) HU718_021380(merB)
MAQMaqu_0243
MARAD0851_16925(merB)
AJORZ95_18695 RZ95_18770
ADVDJ533_01870(merB) DJ533_01955(merB)
AMCMADE_1005535 MADE_1005595
CZACYCME_0208(merB) CYCME_2512(merB2)
HAXIHAALTHF_21200n(merB_1) HAALTHF_21350n(merB_2)
REVHUE57_17010
BSAVWS86_30230
BMKDM80_6094
BMECWJ16_21395
BYIBYI23_E002720(merB) BYI23_E002860
BFNOI25_7578(merB) OI25_8287(merB)
LIMNHKT17_07530
VBOCKY39_25245
GBMGbem_0319
GNTKP003_12325(merB)
DEUDBW_0285(merB)
BRKCWS35_37295
MEEDA075_33940
MMRMmar10_2330
SMAZLH19_05245
SBDATN00_21245
SBARH5V43_01300
GXYGLX_31480
GEAGARCT_03142(merB)
SUWSATW20_00610(merB) SATW20_p1010(merB)
SAUASAAG_03506
SAUZSAZ172_0061(merB) SAZ172_p119(merB)
SAUTSAI1T1_10180(merB)
SAUJSAI2T2_20180(merB)
SAUKSAI3T3_20180(merB)
SAUQSAI4T8_20180(merB)
SAUXSAI6T6_20190(merB)
SAURSABB_01777(merB)
SEPSE_0086
JEAJEM45_07880(merB)
EACEKKI46_16640(merB2) KKI46_16645(merB)
TMRTmar_1607
MMIMMAR_p10(merB)
MDXBTO20_38560
MGROFZ046_13780(merB)
MXEMYXE_04590
MLJMLAC_02650
MBRDMBRA_27840
MSHJMSHI_15300
MKRMKOR_17760 MKOR_34280 MKOR_34290
MGIMflv_3214
MSPMspyr1_25010
MCBMycch_5492 Mycch_5642 Mycch_5855
MDUMDUV_25770
MAUBMAUB_63750
MPHUMPHO_07630
MFLVNCTC10271_02228(merB_1) NCTC10271_02260(merB_2) NCTC10271_02390(merB_3)
MABMAB_p08
CUVCUREI_04375
CDOCDOO_08070
CSPHCSPHI_00990
CGKCGERO_00525(merB)
NAHF5544_04905
NIEKV110_14400(merB)
RHSA3Q41_05015(merB)
RHODAOT96_34060
GBRGbro_2647
GTABCM27_13480
GOCCXX93_04540
GRUGCWB2_23315(merB)
GOILK459_12280(merB)
GHNMVF96_12930(merB) MVF96_24320(merB)
GAMIIHQ52_14150(merB)
DTMBJL86_1893
STRCAA958_19120
SALFSMD44_04521
SGOBtest1122_05730(merB)
LEIFHF024_01840(merB)
LSEF1C12_18150(merB)
MHOSCXR34_00810
MOYCVS54_00759(merB)
ARQBWQ92_19165
ACHAchl_4512
MICKB1A86_00010260(merB)
KSEKsed_25630
JTEASJ30_01305
BRIFDF13_13850(merB)
BCAUI6G59_15415(merB)
NCANoca_4942
NROK8W59_19780(merB)
NGVCDO52_16015
AMDAMED_2700
AMNRAM_13730
AMMAMES_2672
AMZB737_2673
AOIAORI_2677
AJAAJAP_25435
AMYBBKN51_06025
AORISD37_14485
PDXPsed_1314
PBROHOP40_20285(merB) HOP40_35015(merB)
SSYIEKG83_24615 EKG83_24645
ALOCRK55259
SACEGIY23_03330 GIY23_03340(merB)
SNASnas_5374
RXYRxyl_1768 Rxyl_1769
IAMHC251_04795
ERZER308_15625
EUZDVS28_a1446
KBSEPA93_34845(merB)
TTRTter_2087
PMETG4Y79_01330(merB)
MHDMarky_2021
SMUII6J00_08410
BBDBelba_2844
ZPRZPR_4027
MARBCJ263_16230
SALTAO058_06440
SMISLDL76_13295
CGLENCTC11432_01486(merB)
SCASSACC_13720
NVNNVIE_012660
NEVNTE_02676
 » show all
Reference
1  [PMID:9382]
  Authors
Tezuka T, Tonomura K.
  Title
Purification and properties of an enzyme catalyzing the splitting of carbon-mercury linkages from mercury-resistant Pseudomonas K-62 strain. I. Splitting enzyme 1.
  Journal
J Biochem (Tokyo) 80:79-87 (1976)
DOI:10.1093/oxfordjournals.jbchem.a131261
Other DBs
ExplorEnz - The Enzyme Database: 4.99.1.2
IUBMB Enzyme Nomenclature: 4.99.1.2
ExPASy - ENZYME nomenclature database: 4.99.1.2
UM-BBD (Biocatalysis/Biodegradation Database): 4.99.1.2
BRENDA, the Enzyme Database: 4.99.1.2
CAS: 72560-99-7

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