KEGG   ENZYME: 5.1.1.13Help
Entry
EC 5.1.1.13                 Enzyme                                 

Name
aspartate racemase;
D-aspartate racemase;
McyF
Class
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
BRITE hierarchy
Sysname
aspartate racemase
Reaction(IUBMB)
L-aspartate = D-aspartate [RN:R00491]
Reaction(KEGG)
Substrate
L-aspartate [CPD:C00049]
Product
D-aspartate [CPD:C00402]
Comment
Also acts, at half the rate, on L-alanine.
History
EC 5.1.1.13 created 1976
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
Orthology
K01779  aspartate racemase
Genes
ECP: ECP_2853
ECM: EcSMS35_1090
ESO: O3O_09670
ESM: O3M_15610
ESL: O3K_15625
EAL: EAKF1_ch2998
STY: STY4866
STT: t4560
SEX: STBHUCCB_48100
SENT: TY21A_23215
STM: STM4510
SENI: CY43_23485
SPT: SPA4330
SEK: SSPA4021
SEI: SPC_4647
SEC: SCH_4365(pnl)
SHB: SU5_0554
SENS: Q786_22395
SED: SeD_A4912
SEG: SG4340
SEL: SPUL_4499
SET: SEN4271
SENA: AU38_22030
SENO: AU37_22045
SENV: AU39_22065
SENQ: AU40_24660
SENL: IY59_22615
SEEP: I137_21515
SENE: IA1_22030
SBG: SBG_3926
SBZ: A464_4556
KOX: KOX_18745
KOE: A225_2620
CKO: CKO_02076
EBF: D782_2774
PSTS: E05_25020
YPE: YPO2758
YPK: y1592
YPA: YPA_2085
YPN: YPN_2188
YPM: YP_2405(racX)
YPZ: YPZ3_2546
YPD: YPD4_2531
YPX: YPD8_2526
YPH: YPC_1511
YPW: CH59_3645
YPJ: CH55_18
YPV: BZ15_767
YPL: CH46_2343
YPS: YPTB2625
YPO: BZ17_4014
YPY: YPK_1521
YPB: YPTS_2720
YPQ: DJ40_3919
YPU: BZ21_1921
YPR: BZ20_3585
YPC: BZ23_2205
YPF: BZ19_1985
YEN: YE1289
YEY: Y11_01571
YEW: CH47_707
YET: CH48_365
YAL: AT01_1226
YFR: AW19_1914
YIN: CH53_426
YKR: CH54_3871
YRO: CH64_1253
SPE: Spro_3409
SRL: SOD_c33240(ygeA)
SPLY: Q5A_018020
SMAF: D781_3190
SMAR: SM39_3020
SERF: L085_11035
PVA: Pvag_pPag30500(ygeA)
PSTW: DSJ_26250
XBO: XBJ1_0108
XNE: XNC1_4228
XNM: XNC2_4079
XDO: XDD1_0710
XPO: XPG1_1926
PSI: S70_19760
PSX: DR96_2862
ETE: ETEE_2862
HIA: H733_0086
MHT: D648_2320
MHAT: B824_24300
MHAE: F382_06955
MHAM: J450_08085
MHAO: J451_09265
MHAL: N220_01130
MHAQ: WC39_12935
MHAY: VK67_12940
MVI: X808_7980
MVG: X874_8090
BTO: WQG_2330
BTRE: F542_19630
BTRH: F543_21530
BTRA: F544_1900
XCC: XCC1785(ygeA)
XCB: XC_2451
XCP: XCR_2027
XCV: XCV1832
XAX: XACM_1825
XAC: XAC1802(ygeA)
XCI: XCAW_02603(racX)
SML: Smlt3366
SMT: Smal_2793
SMZ: SMD_2938
VAG: N646_4334
VSP: VS_II0630
VTA: B0549(ygeA)
VFI: VF_1547 VF_A0624(ygeA)
PPR: PBPRA2356(STY4866)
PPX: T1E_4880(ygeA)
PMON: X969_10225
PMOT: X970_09885
PFL: PFL_2830
PPRO: PPC_2876
PFS: PFLU_3010
PFB: VO64_0376
PMAN: OU5_0628
PSES: PSCI_5089
PSEM: TO66_14205
PSOS: POS17_3230
PANR: A7J50_2994
ACB: A1S_2202
ABY: ABAYE1354
ABN: AB57_2538
ABX: ABK1_1287
ABH: M3Q_2671
ABAD: ABD1_21980
ABAZ: P795_5955
ABAU: IX87_06990
ABAA: IX88_13550
ACI: ACIAD0318
SFR: Sfri_1897
SAZ: Sama_2886
SSE: Ssed_2728
SPL: Spea_0941
SHL: Shal_0991
SWD: Swoo_1908
SWP: swp_4573
SVO: SVI_2656
SPSW: Sps_01536
ILO: IL1778
PAT: Patl_0005
PSM: PSM_A0877
PSEO: OM33_21520
PSPO: PSPO_b1622
MAQ: Maqu_1062
MHC: MARHY2216
MAD: HP15_1403
MBS: MRBBS_2586(ygeA)
AMAL: I607_18705
AMAE: I876_19080
AMAO: I634_18845
AMAD: I636_19005
AMAI: I635_19855
AMAG: I533_18780
AMAC: MASE_19270
AAUS: EP12_19560
GNI: GNIT_0683
PIN: Ping_2098
FBL: Fbal_0565
MVS: MVIS_2520
SAGA: M5M_06425
LLO: LLO_3361
HCH: HCH_00437
CSA: Csal_0199
HEL: HELO_3136(ygeA)
HAM: HALO3458
HBE: BEI_2545(racD)
APAC: S7S_01200
AHA: AHA_3590
ASA: ASA_3552
AVR: B565_0708
AMED: B224_5791
ASR: WL1483_2547(ygeA)
ACAV: VI35_17105
ECOR: SAMEA4412678_0872(ygeA_1)
CVI: CV_0113
LHK: LHK_00054
RSO: RSc0212
RSE: F504_227
REH: H16_B2421(racX)
RME: Rmet_4003
CGD: CR3_3203
BTQ: BTQ_4440
BTJ: BTJ_5422
BTZ: BTL_3881
BTD: BTI_3753
BTV: BTHA_3996
BTHE: BTN_3777
BTHM: BTRA_4477
BTHA: DR62_3816
BTHL: BG87_3896
BVE: AK36_1745
BCN: Bcen_5934
BCJ: BCAL2215
BCEN: DM39_2216
BCEW: DM40_2783
BCEO: I35_2144
BMU: Bmul_1127
BMJ: BMULJ_02127(racD)
BMK: DM80_2824
BMUL: NP80_2262
BCED: DM42_2945
BUB: BW23_2773
BLAT: WK25_10385
BSEM: WJ12_10800
BPSL: WS57_29305
BMEC: WJ16_11050
BSTG: WT74_11195
BUK: MYA_1928
BUL: BW21_5747
PAPI: SG18_00680
BPE: BP0053
BPC: BPTD_0051
BPER: BN118_3216
BPET: B1917_0055
BPEU: Q425_550
BPT: Bpet2326
BAV: BAV1890
BHO: D560_3606
BHM: D558_3582
PUT: PT7_2778
AMIM: MIM_c05960
AAV: Aave_1663
ACRA: BSY15_2553
VEI: Veis_4736
LIM: L103DPR2_02625(racX)
CFU: CFU_3166
CARE: LT85_1332
RGE: RGE_30070
AZA: AZKH_3014
HHE: HH_0075(ygeA)
CJU: C8J_0077
CJI: CJSA_0076
CJM: CJM1_0084
CJS: CJS3_0084
CJEJ: N564_00078
CJEU: N565_00077
CJEN: N755_00077
CJEI: N135_00085
CJER: H730_00450
CJQ: UC78_0086
CFZ: CSG_15500
CLA: Cla_0734
CCQ: N149_0079
CCF: YSQ_00430
CCY: YSS_00420
CCOI: YSU_00415
CCOF: VC76_00410
CIS: CINS_0712
CPEL: CPEL_0804
CURE: CUREO_0914
SDL: Sdel_0053
SMUL: SMUL_0108
SHAL: SHALO_0097
SULJ: SJPD1_0086
NAM: NAMH_0865
GBM: Gbem_1222
GEM: GM21_3053
GEB: GM18_1086
DMA: DMR_02200
PPRF: DPRO_3023(ygeA)
DPS: DP1920
DAL: Dalk_4759
DAT: HRM2_03110(racD1) HRM2_07710(racD2)
CCX: COCOR_03243(ygeA)
CCRO: CMC5_021350(racD)
DPB: BABL1_gene_779(racX)
MLO: mll4070
SME: SMc01404
SMX: SM11_chr1241(asr)
SMER: DU99_11715
SMD: Smed_1970
RHI: NGR_c19850(asr)
SFD: USDA257_c43990(ygeA)
SIX: BSY16_723
EAD: OV14_3471(asr) OV14_a1652(asr)
ATU: Atu4081
ARA: Arad_2875
AVI: Avi_2787
RLE: RL3216(asr)
RLG: Rleg_2760
RHL: LPU83_2654(asr)
RHT: NT26_2088
OAN: Oant_0550
OAH: DR92_2391
BJA: bll8154
BBT: BBta_4741
RPB: RPB_1147
RPC: RPC_2977
RPD: RPD_1249
AZC: AZC_0103
MNO: Mnod_2741
MAQU: Maq22A_1p37380(racX)
PHL: KKY_3174
HDI: HDIA_4350
SIL: SPO2662
RDE: RD1_0818
KVU: EIO_1875
KVL: KVU_1335
PSF: PSE_0817
RSU: NHU_03861
RHC: RGUI_1873
ZMB: ZZ6_0878
NAR: Saro_1847
SPHP: LH20_10305
SMAZ: LH19_09995
STAX: MC45_07275
SSAN: NX02_26685
SSY: SLG_15700
SPMI: K663_12250
SPHR: BSY17_2390
SPHT: K426_09210
SFLA: SPHFLASMR4Y_02798(racX)
ELI: ELI_02375
AAY: WYH_00966(racX)
ADO: A6F68_01614(racX)
GDJ: Gdia_0972
RCE: RC1_0431
ABS: AZOBR_p1140101(ygeA)
PUB: SAR11_1277(racX)
BSU: BSU34430(racX)
BSR: I33_3562
BSL: A7A1_2662
BSH: BSU6051_34430(racX)
BSUT: BSUB_03671(racX)
BSUL: BSUA_03671(racX)
BSUS: Q433_18855
BSS: BSUW23_16920(racX)
BST: GYO_3777
BSO: BSNT_10028(racX)
BSQ: B657_34430(racX)
BSX: C663_3323(racX)
BAY: RBAM_005490(racX)
BAQ: BACAU_0469(racX)
BYA: BANAU_0462(racX)
BAMP: B938_02515
BAML: BAM5036_0484(racX) BAM5036_2330(racD)
BAMA: RBAU_0436(racD) RBAU_0510(racX)
BAMN: BASU_0421(racD) BASU_0502(racX)
BAMB: BAPNAU_0474(racX)
BAMT: AJ82_03050
BAMY: V529_04910(racX) V529_26840
BMP: NG74_00521(racX)
BAO: BAMF_0460(racX) BAMF_2494(racD)
BAZ: BAMTA208_02390(racX)
BQL: LL3_00490(racX)
BXH: BAXH7_00496(racX)
BQY: MUS_0503(racX)
BAMI: KSO_017005
BAMC: U471_05150
BAMF: U722_02710
BCQ: BCQ_2161(racD) BCQ_2504(asp) BCQ_4567
BTL: BALH_1986(racD) BALH_2374(asp) BALH_4328
BWW: bwei_0136(asp2) bwei_2331(asp1) bwei_2815(asp3)
BCL: ABC3598(racX)
BPU: BPUM_1136
BPUM: BW16_06455
BPUS: UP12_06030
BMH: BMWSH_1591(racD)
BMEG: BG04_494
BJS: MY9_3487
BACB: OY17_05340
BACO: OXB_0271
BACY: QF06_15590
BACL: BS34A_37510(racX)
BALM: BsLM_3449
BEO: BEH_13190
BGY: BGLY_0227
BBEV: BBEV_0086
OIH: OB3391
HHD: HBHAL_4975(racX)
BSE: Bsel_3253
PMS: KNP414_02511(ygeA)
PMW: B2K_14035
PSAB: PSAB_23660
JEO: JMA_03540
KUR: ASO14_444
LLA: L92665(racD)
LLK: LLKF_2493(racD)
LLT: CVCAS_2269(racD)
LLS: lilo_2194(racD)
LLC: LACR_2531
LLM: llmg_2504(racD)
LLR: llh_12960
LLI: uc509_2197(racD)
LLW: kw2_2285
LLJ: LG36_2163(racD)
SMU: SMU_54
SMUA: SMUFR_0047
SSA: SSA_0042
SIE: SCIM_0039
SIB: SIR_0065
SCG: SCI_0061
SCON: SCRE_0061
SCOS: SCR2_0061
LPL: lp_1523(racD)
LPT: zj316_1530(racD)
LPS: LPST_C1201(racD)
LPZ: Lp16_1153
LJO: LJ_0566
LJF: FI9785_1659(racD)
LJH: LJP_1642c
LAC: LBA1817
LAF: SD55_1813
LSA: LCA_0099(racD)
LSL: LSL_0018(racX)
LSI: HN6_00014(racX)
LSJ: LSJ_0021(racX)
LDB: Ldb2043(racD)
LBU: LBUL_1890
LDE: LDBND_1889(racD)
LDL: LBU_1660
LBR: LVIS_1499
LCA: LSEI_0224
LPAP: LBPC_0226
LCB: LCABL_02130(racD)
LCS: LCBD_0213
LCE: LC2W_0204
LGA: LGAS_1732
LRE: Lreu_0282
LRF: LAR_0270
LRT: LRI_1656
LHE: lhv_1852
LHV: lhe_0362
LHH: LBH_1564
LHD: HUO_10355
LFE: LAF_0241
LFF: LBFF_0261
LRH: LGG_00258(racD)
LRG: LRHM_0254
LRL: LC705_00249(racD)
LRA: LRHK_259
LCR: LCRIS_01836(racD)
LAM: LA2_10030
LBH: Lbuc_1238
LBN: LBUCD034_1362(racD)
LKE: WANG_1355(racD)
LAE: LBAT_1444
PPE: PEPE_0662
PPEN: T256_03530
PCE: PECL_1166
EFU: HMPREF0351_11642(racX)
EFM: M7W_1233
EHR: EHR_10610
ECAS: ECBG_00821
EMU: EMQU_1640(racX)
EDU: LIU_09535
THL: TEH_12790
OOE: OEOE_1048
CRN: CAR_c05700(racX)
CTC: CTC_00823
CBE: Cbei_3176
CBZ: Cbs_3176
CBEI: LF65_01577
AMT: Amet_4258
AOE: Clos_0547
CSD: Clst_1610
BFI: CIY_31600
HSD: SD1D_1578
DSY: DSY4104
DHD: Dhaf_1262
EHL: EHLA_2038
OVA: OBV_38560
TMR: Tmar_0886
TTE: TTE1724(RacX)
PMIC: NW74_01815
VPR: Vpar_0296
SRI: SELR_27620(racD) SELR_27950(racD)
PUF: UFO1_1757
CVA: CVAR_2622
RER: RER_54750
REY: O5Y_26080
SGB: WQO_32705
SCT: SCAT_2681
SVE: SVEN_6253
SALS: SLNWT_0524
SALU: DC74_913
SALL: SAZ_05020
STRE: GZL_08391
SLD: T261_0165
STRM: M444_04230
SPRI: SPRI_4483
SALJ: SMD11_6829
SFK: KY5_3235c
AMIN: AUMI_17190
XCE: Xcel_1886
IDO: I598_0466
CFL: Cfla_1731
PFRE: RM25_1552
NCA: Noca_4055
PSIM: KR76_22135
MGG: MPLG2_1868(ygeA) MPLG2_3581(ygeA)
SRO: Sros_4590
GOB: Gobs_2649
KRA: Krad_4072
SEN: SACE_2953(racX) SACE_5069(racX)
AOI: AORI_6491
KAL: KALB_981
ALL: CRK62187
ACTN: L083_6299
BAD: BAD_1087(racD)
BADL: BADO_1138
BDE: BDP_1524
BDN: BBDE_1448
BBI: BBIF_0601(aspA)
BBP: BBPR_0577
BBF: BBB_0557(racD)
BCOR: BCOR_0476
BANG: BBAG_0554
PDO: PSDT_0276
CWO: Cwoe_4374
EYY: EGYY_26840(RacX_(BS))
AEQ: AEQU_1454
OLS: Olsu_1291
MAR: MAE_38620(mcyF)
MPK: VL20_5555
ANB: ANA_C10980(mcyF)
HAU: Haur_4559
TRO: trd_1098(murI)
STI: Sthe_0684
TPED: TPE_1804
SUS: Acid_3866
LBA: Lebu_1754
SBR: SY1_05350
FSC: FSU_0969
GBA: J421_5478
BACC: BRDCF_p670
MBAS: ALGA_3537
RMR: Rmar_2418
CPI: Cpin_3404
MGOT: MgSA37_03168(racX)
GFL: GRFL_1653
FJO: Fjoh_2497
CBAL: M667_10080
EAO: BD94_0750
CTS: Ctha_1448
TLE: Tlet_0908
PMO: Pmob_1573
MARN: LN42_01290
DTN: DTL3_0884
KOL: Kole_0509
NJA: NSJP_2825
MMP: MMP0739
METM: MSMTP_1214
MMET: MCMEM_1206
MPI: Mpet_0441
MBN: Mboo_2031
MPD: MCP_0433
MEB: Abm4_0367
FPL: Ferp_0277
GAC: GACE_0518
GAH: GAH_01169
HSU: HLASF_1687(racD)
HSF: HLASA_1674(racD)
HVO: HVO_B0183
HME: HFX_5011(racX)
PTO: PTO0149
FAI: FAD_0823
PHO: PH0670(PH0670)
PAB: PAB0912(racD-1)
PFU: PF0980
TKO: TK0504
TGA: TGAM_1341(racD-1) TGAM_1356(racD-2)
TSI: TSIB_0542
THS: TES1_0399
ABI: Aboo_0870
LOKI: Lokiarch_06140(racX)
 » show all
Taxonomy
Reference
1  [PMID:4626916]
  Authors
Lamont HC, Staudenbauer WL, Strominger JL.
  Title
Partial purification and characterization of an aspartate racemase from Streptococcus faecalis.
  Journal
J Biol Chem 247:5103-6 (1972)
Reference
2  [PMID:1526977]
  Authors
Yamauchi T, Choi SY, Okada H, Yohda M, Kumagai H, Esaki N, Soda K.
  Title
Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase.
  Journal
J Biol Chem 267:18361-4 (1992)
Reference
3  [PMID:12051922]
  Authors
Liu L, Iwata K, Kita A, Kawarabayasi Y, Yohda M, Miki K.
  Title
Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization.
  Journal
J Mol Biol 319:479-89 (2002)
DOI:10.1016/S0022-2836(02)00296-6
  Sequence
[pho:PH0670]
Reference
4  [PMID:12713441]
  Authors
Sielaff H, Dittmann E, Tandeau De Marsac N, Bouchier C, Von Dohren H, Borner T, Schwecke T.
  Title
The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase.
  Journal
Biochem J 373:909-16 (2003)
DOI:10.1042/BJ20030396
Reference
5  [PMID:15606767]
  Authors
Yamashita T, Ashiuchi M, Ohnishi K, Kato S, Nagata S, Misono H.
  Title
Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum.
  Journal
Eur J Biochem 271:4798-803 (2004)
DOI:10.1111/j.1432-1033.2004.04445.x
  Sequence
[bbf:BBB_0557]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.1.13
IUBMB Enzyme Nomenclature: 5.1.1.13
ExPASy - ENZYME nomenclature database: 5.1.1.13
BRENDA, the Enzyme Database: 5.1.1.13
CAS: 37237-56-2

DBGET integrated database retrieval system