| Entry |
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| Name |
2-aminohexano-6-lactam racemase;
alpha-amino-epsilon-caprolactam racemase
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| Class |
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
 |
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| Sysname |
2-aminohexano-6-lactam racemase
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| Reaction(IUBMB) |
(S)-2-aminohexano-6-lactam = (R)-2-aminohexano-6-lactam [RN: R04736]
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| Reaction(KEGG) |
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| Substrate |
(S)-2-aminohexano-6-lactam [CPD: C02837]
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| Product |
(R)-2-aminohexano-6-lactam [CPD: C05328]
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| Comment |
Contains pyridoxal 5'-phosphate. Also racemises 2-aminopentano-5-lactam (alpha-amino-delta-valerolactam) and 2-amino-4-thiahexano-6-lactam (where S replaces CH2 of C-4). It does not catalyse the racemisation of alpha-amino acids but has some transaminase activity with them.
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| History |
EC 5.1.1.15 created 1999
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| Reference |
1 |
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| Authors |
Ahmed, S.A., Esaki, N., Tanaka, H., Soda, K. |
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| Title |
L-alpha-Amino-beta-thio-epsilon-caprolactam, a new sulfur-containing substrate for alpha-amino-epsilon-caprolactam racemase. |
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| Journal |
FEBS Lett 174:76-79 (1984) |
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| Reference |
|
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| Authors |
Ahmed SA, Esaki N, Tanaka H, Soda K. |
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| Title |
Mechanism of alpha-amino-epsilon-caprolactam racemase reaction. |
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| Journal |
Biochemistry 25:385-8 (1986) |
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| Reference |
|
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| Authors |
Okazaki S, Suzuki A, Mizushima T, Kawano T, Komeda H, Asano Y, Yamane T |
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| Title |
The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 5.1.1.15 |
| ExPASy - ENZYME nomenclature database: | 5.1.1.15 |
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