KEGG   ENZYME: 5.1.3.26
Entry
EC 5.1.3.26                 Enzyme                                 
Name
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase;
GlcNAc-P-P-Und epimerase;
GlcNAc-P-P-Und 4-epimerase;
gne (gene name)
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase
Reaction(IUBMB)
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10554]
Reaction(KEGG)
R10554
Substrate
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C01289]
Product
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Comment
The enzyme is involved in biosynthesis of the repeating tetrasaccharide unit of the O-antigen produced by some Gram-negative bacteria.
History
EC 5.1.3.26 created 2013
Orthology
K19997  GlcNAc-P-P-Und epimerase
Genes
ECEZ3206
ECSECs_2847(gne)
ECFECH74115_2976(gne)
ETWECSP_2797(gne)
ELXCDCO157_2627
ESLO3K_09215
ESOO3O_16405
ESMO3M_09180
ECKEC55989_2298(gne)
ECGE2348C_2184(gne)
EOKG2583_2565(gne)
ELRECO55CA74_12340
ECMEcSMS35_1020(gne)
ECRECIAI1_2117(gne)
ECQECED1_2388(gne)
ECLEcolC_1599
EMAC1192_01700
SBGSBG_1917
SBCSbBS512_E1190(gne)
ESAESA_01176
CSKES15_1414
CSJCSK29544_02495
CDMAFK67_13190
CSIP262_02069
CMJAFK66_006885
CFDCFNIH1_21450
CYOCD187_08940
CPOTFOB25_20225
HDEHDEF_0179(galE_1)
CNTJT31_20440
KCOBWI95_20085
KASKATP_15980
LEFLJPFL01_2722
IZHFEM41_21510
YPYYPK_3179
YSIBF17_13495
YAKACZ76_14280
YMADA391_16660
SMARSM39_2357(gne)
SMACSMDB11_2153(gne)
SMWSMWW4_v1c28970
SPESpro_2896
SRRSerAS9_2978
SRLSOD_c27230(gne)
SRYM621_14820
SPLYQ5A_015045(gnu)
SRSSerAS12_2979
SRASerAS13_2980
SMAFD781_2683
SLQM495_14930
SERFL085_14300
SERSSERRSCBI_13680
SRZAXX16_2369
SERMCLM71_13860
SQUE4343_01560
SFJSAMEA4384070_2913
SOFNCTC11214_03911(rmlB)
SSURATE40_011090
SURIJ0X03_09460
SRHZFO014_19800
SENPKHA73_14235
SFOZ042_22575
GQUAWC35_22200
FSMCCS41_00970
PCVBCS7_06710
PPARA8F97_03570
PANPPSNIH2_05160
MINTC7M51_01871(gnu)
XHOA9255_14900
PRGRB151_044070(galE_3)
PHEINCTC12003_03344
PRQCYG50_16625
ANSArsFIN_07600(gnu)
AETLDL57_00465
EICNT01EI_1309
ETCETAC_05710
EHOA9798_10735
LPVHYN51_14485
LRINCTC12151_01024(galE_1)
XBCELE36_18940
XBAC7S18_03780
PCQPcP3B5_48010(galE_1)
SLJEGC82_14445
SPOLFH971_12795
PCARPC2016_1873
MYAMORIYA_3321
MARQMARGE09_P2537
LADLNCTC12735_01331(galE_3)
MPADKEF85_04055 KEF85_11835
HHKHH1059_04080
OCMCBP12_12885
AQSDKK66_15875
COXE0W60_29830 E0W60_31350
SNIVSFSGTM_06310
PACOAACT_2575
DSFUWK_01606 UWK_02527
REIIE4771_CH00813
RHTNT26_1041
SZOK8M09_21100
BGQX265_13735
BDGLPJ38_34180
XAUXaut_3561
PHLKKY_3120
DSALK1X15_10460
BVRBVIR_903
MLUTJET14_10150
BRND1F64_22760
LABPFJ695_14230
CAKCaul_0135
CHQAQ619_13015
ROTFIV09_18515
RCPRCAP_rcc01936(gne)
PGVSL003B_3042(gne)
RBZB9057_14975
GAKX907_1850
BSTOC0V70_07320
PCELHUB94_27635
FPRACG447_13080
FDUGXM22_10875
DORDesor_5194
DMIDesmer_4163
MHOLK3U96_21885
MPAEK0O64_02915
MRHMycrhN_1275
MAUUNCTC10437_05040(galE_3)
MMORMMOR_59920(gnu)
MAICMAIC_50230(gnu)
MPOFMPOR_19860
ASUNKG104_12840
BCVBcav_1168
PSEIGCE65_04465
HALTIM660_13960
EUZDVS28_a1014
SYNCCB0101_05320
PRCEW14_1482
FGIOP10G_3275
OBTOPIT5_05060
CAACaka_1981
VBSEGM51_07950
MFFMFFC18_01490(galE_1)
PBASSMSP2_01877
TAERGT409_12350
TDETDE_1439
TBETrebr_2227
TPKJO40_09965
TRMJO41_03080
TPHGFUT81_06790
TRZGWP43_02880
SLRL21SP2_3136
ADINH7849_13860
FSUFisuc_0995
FSCFSU_1441
GGRHKW67_12240
GBAJ421_2491
BTHBT_2887
BTHOBtheta7330_02119(rmd)
BFRBF3647
BFSBF9343_1488 BF9343_2511 BF9343_3583
BFGBF638R_2586
BHLBache_1980 Bache_2164 Bache_2248 Bache_2957
BXYBXY_37990
BOABovatus_00886 Bovatus_01171(galE_1) Bovatus_04914(galE_2)
BCELBcellWH2_04981(rmd_3)
BCACCGC64_12060
BISDXK01_010855 DXK01_020645
BVUBVU_2955 BVU_4018
BSABacsa_1196
BDOEL88_07835
BDHGV66_15720 GV66_17420
PETPEIBARAKI_4444
PSACPSM36_1384
PARYA4V02_05275
OSPOdosp_3011
PRUPRU_0452 PRU_1755
PHERprwr041_16330
ALQC7Y71_007870
ADAA5CPEGH6_13570
DRCG0Q07_12735
MCOSGM418_23815
CPICpin_4748
CHIHGWR21_01140
FLSGLV81_01955
PSTYBFS30_06935
PEKFFJ24_019800
PSNPedsa_3243
SPHNBV902_01955
SMIZ4412673_02365(galE_2)
SPHZE3D81_03160
SPHEGFH32_08535
SDJNCTC13534_03419 NCTC13534_03420(galE_1)
MUCMuYL_1759
MGKFSB76_19880
MMABHQ865_06455
SBXCA265_19225
EVIEchvi_4391
ESTDN752_19970
SPIRCWM47_29065
SPIBG8759_28100
FBTD770_16760
FJGBB050_02180(galE_3)
FGLEM308_00720
FSNGS03_00613(fcl_1)
FNKE1750_13660
MARTBTR34_14750
MUTGVT53_17505
NDODDD_3538
FORFORMB_13010
MESQC7H62_1061
EAOBD94_3329
EMNM876_13835
EENBBD30_09955
ELBVO54_03300(galE_3)
EGOBBD34_06100
EGMAYC65_00590
ELZFCS00_14520
CIOCEQ15_13450
CHRZCO230_02280
CCAUEG346_11910
EVAEIB75_15450
EBVF0358_04420
CPBCphamn1_1916
CLIClim_1879
PVICvib_0649
PAAPaes_1748
CACICLOAM1566
TLETlet_0256
TYETHEYE_A0495
 » show all
Reference
1  [PMID:19923219]
  Authors
Rush JS, Alaimo C, Robbiani R, Wacker M, Waechter CJ
  Title
A novel epimerase that converts GlcNAc-P-P-undecaprenol to GalNAc-P-P-undecaprenol in Escherichia coli O157.
  Journal
J Biol Chem 285:1671-80 (2010)
DOI:10.1074/jbc.M109.061630
  Sequence
[ece:Z3206]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.26
IUBMB Enzyme Nomenclature: 5.1.3.26
ExPASy - ENZYME nomenclature database: 5.1.3.26
BRENDA, the Enzyme Database: 5.1.3.26

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