KEGG   ENZYME: 5.1.3.28
Entry
EC 5.1.3.28                 Enzyme                                 
Name
UDP-N-acetyl-L-fucosamine synthase;
WbjD;
Cap5G
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase
Reaction(IUBMB)
UDP-2-acetamido-2,6-dideoxy-beta-L-talose = UDP-N-acetyl-beta-L-fucosamine [RN:R10676]
Reaction(KEGG)
R10676
Substrate
UDP-2-acetamido-2,6-dideoxy-beta-L-talose [CPD:C20768]
Product
UDP-N-acetyl-beta-L-fucosamine [CPD:C20774]
Comment
Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis.
History
EC 5.1.3.28 created 2014
Pathway
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K24258  UDP-N-acetyl-L-fucosamine synthase
Genes
EOJ: ECO26_2943(fnl3)
ECOO: ECRM13514_2752(fnlC)
ECOH: ECRM13516_2620(fnlC)
EAB: ECABU_c23600(fnlC)
ELP: P12B_c2136(capG)
SBZ: A464_2211
SBV: N643_09260
ECAN: CWI88_07920
CCON: AFK62_12525
CUI: AFK65_12835
CTU: CTU_27290
CFAR: CI104_16430
CIE: AN232_13740 AN232_31065
LEA: GNG26_14685
YFR: AW19_2185
YKR: CH54_3601
PALH: B1H58_14585
PGZ: C2E15_13430
PTT: VY86_07670
ASY: AUT07_00150(wbpI)
OPO: DSM2777_17410
HPAS: JL26_05865
PMU: PM1009(wbjD)
PMV: PMCN06_0221(wecB)
PUL: NT08PM_0218
PMP: Pmu_01520(wbjD)
PMUL: DR93_960
PDAG: 4362423_00267(wbjD)
LUS: E5843_03565
THES: FHQ07_00280
THEH: G7079_07110(wecB)
VCZ: VAB027_3590
VFL: AL536_19545
VFI: VF_0193(rffE)
PMAI: CF386_03160
PAP: PSPA7_1982
PAEB: NCGM1900_3149(wbjD)
PSG: G655_09075
PAEU: BN889_06736
PPG: PputGB1_1375
PPUH: B479_06965
PMOS: O165_002655
PMOL: CLJ08_05525
PCI: PCH70_40490
PFS: PFLU_1659(fnl3)
PMAN: OU5_1707
PTV: AA957_05805
PFW: PF1751_v1c16230
PFF: PFLUOLIPICF700205
PEN: PSEEN1502
PBA: PSEBR_a1567
PFZ: AV641_08235
PSEC: CCOS191_3870
PUM: HGP31_08960(wecB)
PPSH: G5J76_11630(wecB)
PVK: EPZ47_08545
PMAO: PMYSY11_1869
PTRT: HU722_0009240(wecB)
PXN: HU772_006865(wecB)
PNN: KEM63_05745(wecB)
PFAK: KSS94_07165(wecB)
PORY: EJA05_07545
HAES: LO767_04845(wecB)
MBS: MRBBS_2500(wecB)
MLQ: ASQ50_04325
MARA: D0851_05370
PALI: A3K91_0728
PSYP: E5677_09745
ABZ: ABZJ_00089
ABR: ABTJ_03752
ABAD: ABD1_00600(wecB)
ABAB: BJAB0715_00106
ABAU: IX87_14890
ABAL: ABLAC_36940
AHL: AHTJS_16400
AID: CTZ23_14890
ABER: BSR55_00415
AVB: RYU24_00900(wecB)
SBP: Sbal223_1482
SJA: SJ2017_1341
PNG: PNIG_a0509(wecB)
PMAA: CPA52_14010
FTD: AS84_1080
FTY: CH70_512
FCF: FNFX1_1462
FCN: FN3523_1489
FRC: KX01_1759
AFRI: E3E15_05640
AII: E4K63_02195
TXA: HQN79_09380(wecB)
TANI: J8380_09235(wecB)
TEE: Tel_08640
GAI: IMCC3135_22515(wbpI)
APAC: S7S_10525
MPRF: J8N69_05370(wecB)
NIK: F5I99_05210
AAJ: BOQ57_14815
AVR: B565_2779
OCE: GU3_12820
ZDF: AN401_12705
CFON: HZU75_02530(wecB)
CPAU: EHF44_09270
BSTL: BBJ41_07745
PDQ: CL55_00003320
PPNO: DA70_17330
PPNM: LV28_13495
PRB: X636_09590
POX: MB84_03545
CABA: SBC2_28920(wbpI)
AXY: AXYL_06296
AIS: BUW96_24750
AAQU: D3M96_17710
ODI: ODI_R2815
BOZ: DBV39_04040
PACR: FXN63_16090
PARK: LSG25_14385(wecB)
RAC: RA876_17030
PVAC: HC248_00279(wbpI)
AJS: Ajs_3032
ACIP: CBP36_03070
ACIS: CBP35_15870
VBO: CKY39_06065
COF: FOZ74_09630
CBX: Cenrod_0486(wecB-1)
HYR: BSY239_4259
HYB: Q5W_21535
HYN: F9K07_02080
SIMP: C6571_03415
CBAA: SRAA_0130
CBAB: SMCB_0541
KIA: G8A07_07105(wecB)
HSE: Hsero_4220(wecB)
HSZ: ACP92_21080
GCA: Galf_2832
EBA: ebA5890
APET: ToN1_17460(wecB)
AZA: AZKH_0897
TMZ: Tmz1t_3803
THU: AC731_013185
THK: CCZ27_21925
AZQ: G3580_04700(wecB)
APP: CAP2UW1_0114
SULG: FJR48_03850
SSEI: FJR45_04475
ABT: ABED_0640
AMYT: AMYT_0883 AMYT_0912
GPI: GPICK_06390
GUR: Gura_1696
GBM: Gbem_1623(wbjD)
DEU: DBW_1520
DFL: DFE_2837
DTO: TOL2_C08110(wecB)
DMM: dnm_096980(wecB2)
DEK: DSLASN_12290(rffE)
RLU: RLEG12_13415
RHT: NT26_3155(capG)
SZO: K8M09_15610(wecB)
SNO: Snov_3209
ANC: GBB76_10280
HDN: Hden_0187
HDT: HYPDE_23138
DEA: FPZ08_13240
MARU: FIU81_15475(wbpI)
PAMO: BAR1_15465
SMAG: AN936_18590
SPHO: C3E99_07085
SECH: B18_28740
SPHG: AZE99_15320
SPHL: LPB140_06510
BFW: B5J99_05770
PHAO: HF685_11055(wecB)
PORL: BG023_111104
PHZ: CHX26_09065
TII: DY252_04925
BBA: Bd1695(capG)
MFN: Ga0123462_1141
BCR: BCAH187_A5442
BNC: BCN_5194
BTHU: YBT1518_33536
BACI: B1NLA3E_20915
BFD: NCTC4823_03154(mnaA_3)
LYZ: DCE79_04815
LPAK: GDS87_03480
HMN: HM131_05140
VIM: GWK91_11140
BMUR: ABE28_016000
PPSR: I6J18_19585(wecB)
PSYO: PB01_03870
PRD: F7984_17690
GRC: GI584_20430
SCIB: HUG20_11460(wecB)
NMK: CHR53_26465
MSEM: GMB29_25210
BOU: I5818_12870(wecB)
SAU: SA0150(capG)
SAV: SAV0155(capG)
SAW: SAHV_0154(capG)
SAH: SaurJH1_0146
SAJ: SaurJH9_0141
SAM: MW0130(cap8G)
SAS: SAS0130
SAR: SAR0157(capG)
SAC: SACOL0142(cap5G)
SAA: SAUSA300_0158(cap5G)
SAO: SAOUHSC_00120
SAE: NWMN_0101(capG)
SAD: SAAV_0123(cap5G)
SUU: M013TW_0145
SUV: SAVC_00545
SUE: SAOV_0102
SUJ: SAA6159_00139(cap5G)
SUK: SAA6008_00133(cap5G)
SUC: ECTR2_112
SUT: SAT0131_00145
SUQ: HMPREF0772_10343
SUZ: MS7_0149
SUD: ST398NM01_0169
SUX: SAEMRSA15_01210(capG)
SUW: SATW20_01660(capG)
SUG: SAPIG0169
SUF: SARLGA251_01290(capG)
SAUA: SAAG_00638
SAUE: RSAU_000109(capG)
SAUN: SAKOR_00135
SAUS: SA40_0122(capG)
SAUU: SA957_0137(capG)
SAUG: SA268_0134(capG)
SAUZ: SAZ172_0165
SAUT: SAI1T1_2001100(capG)
SAUJ: SAI2T2_1001100(capG)
SAUK: SAI3T3_1001100(capG)
SAUQ: SAI4T8_1001100(capG)
SAUV: SAI7S6_1001100(capG)
SAUW: SAI5S5_1001090(capG)
SAUX: SAI6T6_1001100(capG)
SAUY: SAI8T7_1001100(capG)
SAUF: X998_0138
SAB: SAB0096(capG)
SUY: SA2981_0156(capG)
SAUB: C248_0144(capG)
SAUM: BN843_1610
SAUC: CA347_166
SAUR: SABB_01686(wecB)
SAUI: AZ30_00815
SAUD: CH52_04950
SAMS: NI36_00710
SUH: SAMSHR1132_01290
SHA: SH0394(capG)
SHH: ShL2_00299(cap5G)
SLG: SLGD_00329
SLN: SLUG_03260(capG)
SHU: SHYC_02150
SAGQ: EP23_07985(wecB)
SARL: SAP2_22720
SSH: NCTC13712_00110(mnaA_1)
SDB: CNQ82_05970
MVT: I6J10_00255(wecB)
MACR: BHM04_11835
SHV: AAT16_04060
LGZ: NCTC10812_01729(mnaA_1)
EAT: EAT1b_1193
EAP: KB235_04670(wecB) KB235_04835(wecB)
PAEH: H70357_28050
PAEJ: H70737_24325
PSON: JI735_06095(wecB)
PDH: B9T62_25300
SOB: CSE16_04880
PLN: Plano_2326
PLL: I858_011155
PMAR: B0X71_14585
PLAY: DNR44_008535
LLR: llh_0480
SPN: SP_0360(cps4L)
EFD: EFD32_1893
EGA: AL523_16075
MPS: MPTP_0533
MPX: MPD5_1384
VFV: K5K99_13350(wecB)
AUN: AWM73_05380
AUI: APT62_03045
ASAN: AWM72_07000
CARC: NY10_926
CARN: FPV25_02525
JEP: BW721_05890
JAR: G7057_08185(wecB) G7057_08370(wecB)
CCHV: BTM20_03720
CIA: BEN51_06340
CGAS: J1C67_09580(wecB)
CCAA: KQH81_02660(wecB)
GFE: Gferi_11330
FSA: C5Q98_00740
CTHD: CDO33_01155
RAL: Rumal_3598
FPR: FP2_31560
BPB: bpr_I0346
BFI: CIY_26620
BHU: bhn_I0402
BYL: A4V09_01950
CPY: Cphy_3502
CSO: CLS_28760
HSD: SD1D_1289
PXV: FXF36_15575
ACEL: acsn021_22610(capG)
ACHT: bsdcttw_26870(capG)
RGN: RGna_12015
CBOL: CGC65_13105
EAC: EAL2_c20130(wecB)
SLP: Slip_0165
CALK: HUE98_16960(wecB)
DDH: Desde_3834
DDL: Desdi_2895
DRS: DEHRE_09880
DRM: Dred_3031
AACX: DEACI_3974
ELM: ELI_4557
ELIM: B2M23_15720
ALKA: J0B03_04220(wecB)
CBAR: PATL70BA_0361
ACAE: HYG86_00845(wecB)
AMIC: Ami3637_06435
CKI: Calkr_2279
CLC: Calla_0174
TXY: Thexy_1802
AFT: BBF96_11315
PUF: UFO1_4149
ERH: ERH_0860(wecB)
ERS: K210_02155
ERL: AOC36_02530
ERI: EEI45_05835
ERD: G7062_06985(wecB)
EIO: H9L01_07870(wecB)
EUC: EC1_02770 EC1_12040
AARG: Aargi30884_24450
ERM: EYR00_04315
LCG: L3BBH23_17540
ACL: ACL_1043(wecB2)
AAXA: NCTC10138_00338(mnaA)
MBJ: KQ51_00736(wbpI)
CMD: B841_09305
CPEG: CPELA_00505(wbpI)
CGK: CGERO_00495(wbpI)
CPSO: CPPEL_00480(wbpI)
CSUR: N24_0492
DIZ: CT688_13280
LXX: Lxx05070(wbjD)
LXY: O159_05200
AGY: ATC03_14110
MYL: C3E77_02895
AGG: C1N71_10860
MANT: BHD05_03285
ARU: ASPU41_19420
AJG: KKR91_12380(wecB)
APN: Asphe3_25560
PSEY: GU243_10745
RSA: RSal33209_1611
KSE: Ksed_18640
CFL: Cfla_0759
JME: EEW87_010820
DCO: SAMEA4475696_2249(mnaA)
AUS: IPK37_01970(wecB)
MICG: GJV80_08205
TDF: H9L22_12375(wecB)
NDK: I601_1758(wbpI)
NOI: FCL41_02140
NOO: FE634_12360
NDP: E2C04_02760
NSN: EXE58_10535
NPI: G7071_07155(wecB)
MICH: FJK98_09920
MCAB: HXZ27_11025(wecB)
MSAG: GCM10017556_43860(rffE)
MCRA: ID554_03055(wecB)
PLK: CIK06_10370
PLAB: C6361_29220
PLAT: C6W10_06220
PSUU: Psuf_011590
VER: HUT12_10085(wecB)
FLH: EJ997_04860
ATQ: GH723_15165
EGD: GS424_003820
CSTC: LK434_09635
DMR: Deima_2966
DPT: Deipr_2060
DPD: Deipe_0922
DEZ: DKM44_11280
DFC: DFI_17505
OBG: Verru16b_02064(wbpI)
ROO: G5S37_11400(wecB)
RUL: UC8_50250(wbpI)
MFF: MFFC18_22190(wbpI)
PND: Pla175_07570(wbpI)
PBU: L21SP3_00952(wbpI_1)
PBP: STSP1_00659(wbpI_1)
VBC: C5Q97_18395
TBE: Trebr_1801
SCD: Spica_0526
SPER: EW093_13170
SBU: SpiBuddy_0259
LIL: LA_1645(wecB)
LIE: LIF_A1331(wecB)
LIC: LIC_12139(rffE)
LIS: LIL_12273(wecB)
LMAY: DPV73_15780
LWL: FHG68_08495
FNC: HMPREF0946_01287
FPD: CTM68_07395
FVA: FV113G1_07640(wbpI)
FUL: C4N20_02500
FMO: C4N19_00415
FPEI: C4N17_00400
CPOR: BED41_13420 BED41_15225
FSU: Fisuc_2681 Fisuc_2695
FSC: FSU_3249 FSU_3262
BTH: BT_0383
BTHO: Btheta7330_02109(wbpI_2) Btheta7330_02997(wbpI_4)
BFR: BF1108 BF1844.1
BFS: BF9343_1827(wcgT)
BFG: BF638R_1090 BF638R_1879
BFB: VU15_04780 VU15_07840
BHL: Bache_2246
BCEL: BcellWH2_04979(wbpI_2)
BHF: C3V43_13535
BUN: Bun01g_26130
BFE: K6V30_14850 K6V30_24435
BNO: K8P02_02080(wecB)
BVU: BVU_0692 BVU_1542
PBT: ING2E5B_0565
PPN: Palpr_0957
PDI: BDI_0574 BDI_3833
PARC: CI960_13470
PMER: INE87_00425(wbpI)
PGOL: K6V26_10515(wecB) K6V26_11945(wecB)
PJO: LK449_12400
BUY: D8S85_13775
PRU: PRU_0103
PCOI: LK433_14510
ALQ: C7Y71_007850
APUT: L6V35_00850
RBC: BN938_0768 BN938_1958
TTZ: FHG85_00425
BACC: BRDCF_p1470
DORI: FH5T_21515
CPI: Cpin_4750
CHIH: GWR21_01130(wecB)
NIA: A8C56_07975
PCM: AY601_4545
PSTY: BFS30_06925
SHT: KO02_22555
SPHZ: E3D81_15980
MDA: IPZ59_16895(wecB)
ALS: DJ013_17380
FPS: FP1285(fnlC)
FPC: FPSM_02197
FPY: FPG101_11010
FPQ: IB65_06060
FPV: IA03_06165
FPW: IA04_06070
FPK: IA06_06105
FBR: FBFL15_1034(fnlC)
FIN: KQS_03325(fnlC)
FGL: EM308_00740
FKI: FK004_09025
FEN: J0383_14330(wecB)
COC: Coch_1112
CCM: Ccan_23360
CAPH: CGC49_04765
MART: BTR34_14760
CLY: Celly_2636
CBAT: M666_12270
KDI: Krodi_2766
DDO: I597_2181(wbpI)
MLT: VC82_2497
NDO: DDD_3540(fnlC)
POB: LPB03_07075
MYR: MYRA21_3292
TDI: AUW17_02395
MESQ: C7H62_1056
MARX: INR76_09915(wecB)
SINH: LS482_11760(wecB)
ASAG: FGM00_01230
ELZ: FCS00_14715
CIH: ATE47_11260
CHH: A0O34_14040
CIO: CEQ15_13460
CHRY: CEY12_09715
CHRZ: CO230_02270
CARH: EGY05_16405
CSHA: EG350_15230
CNK: EG343_08465
CJT: EG359_09450
CIL: EG358_16290
CGLE: NCTC11432_02308(mnaA)
CTAI: NCTC12078_01303(mnaA)
CTAK: 4412677_01079(mnaA)
CSAL: NBC122_00351(wbpI_1) NBC122_02874(wbpI_2)
CBP: EB354_02700
CJG: NCTC13459_02734(mnaA)
CANT: NCTC13489_01521(mnaA)
KHI: EG338_06415
CNR: EB819_08325
ESTE: HNV03_12275(wecB)
BBAU: AEM51_06825
CLZ: BIU88_00475
PPH: Ppha_0560
THER: Y592_04245
FPE: Ferpe_0106
FIA: NA23_00525
DTN: DTL3_0981
MINF: MESINF_0678
CABY: Cabys_3396
NMV: NITMOv2_3487
BBGW: UT28_C0001G0406
MEF: MSWH1_3012
NCL: C5F47_00705
 » show all
Reference
1  [PMID:12464616]
  Authors
Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS
  Title
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
  Journal
J Biol Chem 278:3615-27 (2003)
DOI:10.1074/jbc.M203867200
Reference
2  [PMID:15778500]
  Authors
Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS
  Title
Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
  Journal
J Biol Chem 280:19535-42 (2005)
DOI:10.1074/jbc.M500612200
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.28
IUBMB Enzyme Nomenclature: 5.1.3.28
ExPASy - ENZYME nomenclature database: 5.1.3.28
BRENDA, the Enzyme Database: 5.1.3.28

  All links  
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (11685)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (532)   
   KEGG MGENES (11152)   
Protein sequence (10)   
   UniProt (10)   
DNA sequence (24)   
   GenBank (12)   
   EMBL (12)   
All databases (11728)   

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