KEGG   ENZYME: 5.1.3.28
Entry
EC 5.1.3.28                 Enzyme                                 
Name
UDP-N-acetyl-L-fucosamine synthase;
WbjD;
Cap5G
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase
Reaction(IUBMB)
UDP-2-acetamido-2,6-dideoxy-beta-L-talose = UDP-N-acetyl-beta-L-fucosamine [RN:R10676]
Reaction(KEGG)
R10676
Substrate
UDP-2-acetamido-2,6-dideoxy-beta-L-talose [CPD:C20768]
Product
UDP-N-acetyl-beta-L-fucosamine [CPD:C20774]
Comment
Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis.
History
EC 5.1.3.28 created 2014
Pathway
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K24258  UDP-N-acetyl-L-fucosamine synthase
Genes
EOJECO26_2943(fnl3)
ECOOECRM13514_2752(fnlC)
ECOHECRM13516_2620(fnlC)
EABECABU_c23600(fnlC)
ELPP12B_c2136(capG)
SBZA464_2211
SBVN643_09260
ECANCWI88_07920
CCONAFK62_12525
CUIAFK65_12835
CTUCTU_27290
CFARCI104_16430
CIEAN232_13740 AN232_31065
LEAGNG26_14685
YFRAW19_2185
YKRCH54_3601
PALHB1H58_14585
PGZC2E15_13430
PTTVY86_07670
ASYAUT07_00150(wbpI)
OPODSM2777_17410
HPASJL26_05865
PMUPM1009(wbjD)
PMVPMCN06_0221(wecB)
PULNT08PM_0218
PMPPmu_01520(wbjD)
PMULDR93_960
PDAG4362423_00267(wbjD)
LUSE5843_03565
THESFHQ07_00280
THEHG7079_07110(wecB)
VCZVAB027_3590
VFLAL536_19545
VFIVF_0193(rffE)
PMAICF386_03160
PAPPSPA7_1982
PAEBNCGM1900_3149(wbjD)
PSGG655_09075
PAEUBN889_06736
PPGPputGB1_1375
PPUHB479_06965
PMOSO165_002655
PMOLCLJ08_05525
PCIPCH70_40490
PFSPFLU_1659(fnl3)
PMANOU5_1707
PTVAA957_05805
PFWPF1751_v1c16230
PFFPFLUOLIPICF700205
PENPSEEN1502
PBAPSEBR_a1567
PFZAV641_08235
PSECCCOS191_3870
PUMHGP31_08960(wecB)
PPSHG5J76_11630(wecB)
PVKEPZ47_08545
PMAOPMYSY11_1869
PTRTHU722_0009240(wecB)
PXNHU772_006865(wecB)
PNNKEM63_05745(wecB)
PFAKKSS94_07165(wecB)
PORYEJA05_07545
HAESLO767_04845(wecB)
MBSMRBBS_2500(wecB)
MLQASQ50_04325
MARAD0851_05370
PALIA3K91_0728
PSYPE5677_09745
ABZABZJ_00089
ABRABTJ_03752
ABADABD1_00600(wecB)
ABABBJAB0715_00106
ABAUIX87_14890
ABALABLAC_36940
AHLAHTJS_16400
AIDCTZ23_14890
ABERBSR55_00415
AVBRYU24_00900(wecB)
SBPSbal223_1482
SJASJ2017_1341
PNGPNIG_a0509(wecB)
PMAACPA52_14010
FTDAS84_1080
FTYCH70_512
FCFFNFX1_1462
FCNFN3523_1489
FRCKX01_1759
AFRIE3E15_05640
AIIE4K63_02195
TXAHQN79_09380(wecB)
TANIJ8380_09235(wecB)
TEETel_08640
GAIIMCC3135_22515(wbpI)
APACS7S_10525
MPRFJ8N69_05370(wecB)
NIKF5I99_05210
AAJBOQ57_14815
AVRB565_2779
OCEGU3_12820
ZDFAN401_12705
CFONHZU75_02530(wecB)
CPAUEHF44_09270
BSTLBBJ41_07745
PDQCL55_00003320
PPNODA70_17330
PPNMLV28_13495
PRBX636_09590
POXMB84_03545
CABASBC2_28920(wbpI)
AXYAXYL_06296
AISBUW96_24750
AAQUD3M96_17710
ODIODI_R2815
BOZDBV39_04040
PACRFXN63_16090
PARKLSG25_14385(wecB)
RACRA876_17030
PVACHC248_00279(wbpI)
AJSAjs_3032
ACIPCBP36_03070
ACISCBP35_15870
VBOCKY39_06065
COFFOZ74_09630
CBXCenrod_0486(wecB-1)
HYRBSY239_4259
HYBQ5W_21535
HYNF9K07_02080
SIMPC6571_03415
CBAASRAA_0130
CBABSMCB_0541
KIAG8A07_07105(wecB)
HSEHsero_4220(wecB)
HSZACP92_21080
GCAGalf_2832
EBAebA5890
APETToN1_17460(wecB)
AZAAZKH_0897
TMZTmz1t_3803
THUAC731_013185
THKCCZ27_21925
AZQG3580_04700(wecB)
APPCAP2UW1_0114
SULGFJR48_03850
SSEIFJR45_04475
ABTABED_0640
AMYTAMYT_0883 AMYT_0912
GPIGPICK_06390
GURGura_1696
GBMGbem_1623(wbjD)
DEUDBW_1520
DFLDFE_2837
DTOTOL2_C08110(wecB)
DMMdnm_096980(wecB2)
DEKDSLASN_12290(rffE)
RLURLEG12_13415
RHTNT26_3155(capG)
SZOK8M09_15610(wecB)
SNOSnov_3209
ANCGBB76_10280
HDNHden_0187
HDTHYPDE_23138
DEAFPZ08_13240
MARUFIU81_15475(wbpI)
PAMOBAR1_15465
SMAGAN936_18590
SPHOC3E99_07085
SECHB18_28740
SPHGAZE99_15320
SPHLLPB140_06510
BFWB5J99_05770
PHAOHF685_11055(wecB)
PORLBG023_111104
PHZCHX26_09065
TIIDY252_04925
BBABd1695(capG)
MFNGa0123462_1141
BCRBCAH187_A5442
BNCBCN_5194
BTHUYBT1518_33536
BACIB1NLA3E_20915
BFDNCTC4823_03154(mnaA_3)
LYZDCE79_04815
LPAKGDS87_03480
HMNHM131_05140
VIMGWK91_11140
BMURABE28_016000
PPSRI6J18_19585(wecB)
PSYOPB01_03870
PRDF7984_17690
GRCGI584_20430
SCIBHUG20_11460(wecB)
NMKCHR53_26465
MSEMGMB29_25210
BOUI5818_12870(wecB)
SAUSA0150(capG)
SAVSAV0155(capG)
SAWSAHV_0154(capG)
SAHSaurJH1_0146
SAJSaurJH9_0141
SAMMW0130(cap8G)
SASSAS0130
SARSAR0157(capG)
SACSACOL0142(cap5G)
SAASAUSA300_0158(cap5G)
SAOSAOUHSC_00120
SAENWMN_0101(capG)
SADSAAV_0123(cap5G)
SUUM013TW_0145
SUVSAVC_00545
SUESAOV_0102
SUJSAA6159_00139(cap5G)
SUKSAA6008_00133(cap5G)
SUCECTR2_112
SUTSAT0131_00145
SUQHMPREF0772_10343
SUZMS7_0149
SUDST398NM01_0169
SUXSAEMRSA15_01210(capG)
SUWSATW20_01660(capG)
SUGSAPIG0169
SUFSARLGA251_01290(capG)
SAUASAAG_00638
SAUERSAU_000109(capG)
SAUNSAKOR_00135
SAUSSA40_0122(capG)
SAUUSA957_0137(capG)
SAUGSA268_0134(capG)
SAUZSAZ172_0165
SAUTSAI1T1_2001100(capG)
SAUJSAI2T2_1001100(capG)
SAUKSAI3T3_1001100(capG)
SAUQSAI4T8_1001100(capG)
SAUVSAI7S6_1001100(capG)
SAUWSAI5S5_1001090(capG)
SAUXSAI6T6_1001100(capG)
SAUYSAI8T7_1001100(capG)
SAUFX998_0138
SABSAB0096(capG)
SUYSA2981_0156(capG)
SAUBC248_0144(capG)
SAUMBN843_1610
SAUCCA347_166
SAURSABB_01686(wecB)
SAUIAZ30_00815
SAUDCH52_04950
SAMSNI36_00710
SUHSAMSHR1132_01290
SHASH0394(capG)
SHHShL2_00299(cap5G)
SLGSLGD_00329
SLNSLUG_03260(capG)
SHUSHYC_02150
SAGQEP23_07985(wecB)
SARLSAP2_22720
SSHNCTC13712_00110(mnaA_1)
SDBCNQ82_05970
MVTI6J10_00255(wecB)
MACRBHM04_11835
SHVAAT16_04060
LGZNCTC10812_01729(mnaA_1)
EATEAT1b_1193
EAPKB235_04670(wecB) KB235_04835(wecB)
PAEHH70357_28050
PAEJH70737_24325
PSONJI735_06095(wecB)
PDHB9T62_25300
SOBCSE16_04880
PLNPlano_2326
PLLI858_011155
PMARB0X71_14585
PLAYDNR44_008535
LLRllh_0480
SPNSP_0360(cps4L)
EFDEFD32_1893
EGAAL523_16075
MPSMPTP_0533
MPXMPD5_1384
VFVK5K99_13350(wecB)
AUNAWM73_05380
AUIAPT62_03045
ASANAWM72_07000
CARCNY10_926
CARNFPV25_02525
JEPBW721_05890
JARG7057_08185(wecB) G7057_08370(wecB)
CCHVBTM20_03720
CIABEN51_06340
CGASJ1C67_09580(wecB)
CCAAKQH81_02660(wecB)
GFEGferi_11330
FSAC5Q98_00740
CTHDCDO33_01155
RALRumal_3598
FPRFP2_31560
BPBbpr_I0346
BFICIY_26620
BHUbhn_I0402
BYLA4V09_01950
CPYCphy_3502
CSOCLS_28760
HSDSD1D_1289
PXVFXF36_15575
ACELacsn021_22610(capG)
ACHTbsdcttw_26870(capG)
RGNRGna_12015
CBOLCGC65_13105
EACEAL2_c20130(wecB)
SLPSlip_0165
CALKHUE98_16960(wecB)
DDHDesde_3834
DDLDesdi_2895
DRSDEHRE_09880
DRMDred_3031
AACXDEACI_3974
ELMELI_4557
ELIMB2M23_15720
ALKAJ0B03_04220(wecB)
CBARPATL70BA_0361
ACAEHYG86_00845(wecB)
AMICAmi3637_06435
CKICalkr_2279
CLCCalla_0174
TXYThexy_1802
AFTBBF96_11315
PUFUFO1_4149
ERHERH_0860(wecB)
ERSK210_02155
ERLAOC36_02530
ERIEEI45_05835
ERDG7062_06985(wecB)
EIOH9L01_07870(wecB)
EUCEC1_02770 EC1_12040
AARGAargi30884_24450
ERMEYR00_04315
LCGL3BBH23_17540
ACLACL_1043(wecB2)
AAXANCTC10138_00338(mnaA)
MBJKQ51_00736(wbpI)
CMDB841_09305
CPEGCPELA_00505(wbpI)
CGKCGERO_00495(wbpI)
CPSOCPPEL_00480(wbpI)
CSURN24_0492
DIZCT688_13280
LXXLxx05070(wbjD)
LXYO159_05200
AGYATC03_14110
MYLC3E77_02895
AGGC1N71_10860
MANTBHD05_03285
ARUASPU41_19420
AJGKKR91_12380(wecB)
APNAsphe3_25560
PSEYGU243_10745
RSARSal33209_1611
KSEKsed_18640
CFLCfla_0759
JMEEEW87_010820
DCOSAMEA4475696_2249(mnaA)
AUSIPK37_01970(wecB)
MICGGJV80_08205
TDFH9L22_12375(wecB)
NDKI601_1758(wbpI)
NOIFCL41_02140
NOOFE634_12360
NDPE2C04_02760
NSNEXE58_10535
NPIG7071_07155(wecB)
MICHFJK98_09920
MCABHXZ27_11025(wecB)
MSAGGCM10017556_43860(rffE)
MCRAID554_03055(wecB)
PLKCIK06_10370
PLABC6361_29220
PLATC6W10_06220
PSUUPsuf_011590
VERHUT12_10085(wecB)
FLHEJ997_04860
ATQGH723_15165
EGDGS424_003820
CSTCLK434_09635
DMRDeima_2966
DPTDeipr_2060
DPDDeipe_0922
DEZDKM44_11280
DFCDFI_17505
OBGVerru16b_02064(wbpI)
ROOG5S37_11400(wecB)
RULUC8_50250(wbpI)
MFFMFFC18_22190(wbpI)
PNDPla175_07570(wbpI)
PBUL21SP3_00952(wbpI_1)
PBPSTSP1_00659(wbpI_1)
VBCC5Q97_18395
TBETrebr_1801
SCDSpica_0526
SPEREW093_13170
SBUSpiBuddy_0259
LILLA_1645(wecB)
LIELIF_A1331(wecB)
LICLIC_12139(rffE)
LISLIL_12273(wecB)
LMAYDPV73_15780
LWLFHG68_08495
FNCHMPREF0946_01287
FPDCTM68_07395
FVAFV113G1_07640(wbpI)
FULC4N20_02500
FMOC4N19_00415
FPEIC4N17_00400
CPORBED41_13420 BED41_15225
FSUFisuc_2681 Fisuc_2695
FSCFSU_3249 FSU_3262
BTHBT_0383
BTHOBtheta7330_02109(wbpI_2) Btheta7330_02997(wbpI_4)
BFRBF1108 BF1844.1
BFSBF9343_1827(wcgT)
BFGBF638R_1090 BF638R_1879
BFBVU15_04780 VU15_07840
BHLBache_2246
BCELBcellWH2_04979(wbpI_2)
BHFC3V43_13535
BUNBun01g_26130
BFEK6V30_14850 K6V30_24435
BNOK8P02_02080(wecB)
BVUBVU_0692 BVU_1542
PBTING2E5B_0565
PPNPalpr_0957
PDIBDI_0574 BDI_3833
PARCCI960_13470
PMERINE87_00425(wbpI)
PGOLK6V26_10515(wecB) K6V26_11945(wecB)
PJOLK449_12400
BUYD8S85_13775
PRUPRU_0103
PCOILK433_14510
ALQC7Y71_007850
APUTL6V35_00850
RBCBN938_0768 BN938_1958
TTZFHG85_00425
BACCBRDCF_p1470
DORIFH5T_21515
CPICpin_4750
CHIHGWR21_01130(wecB)
NIAA8C56_07975
PCMAY601_4545
PSTYBFS30_06925
SHTKO02_22555
SPHZE3D81_15980
MDAIPZ59_16895(wecB)
ALSDJ013_17380
FPSFP1285(fnlC)
FPCFPSM_02197
FPYFPG101_11010
FPQIB65_06060
FPVIA03_06165
FPWIA04_06070
FPKIA06_06105
FBRFBFL15_1034(fnlC)
FINKQS_03325(fnlC)
FGLEM308_00740
FKIFK004_09025
FENJ0383_14330(wecB)
COCCoch_1112
CCMCcan_23360
CAPHCGC49_04765
MARTBTR34_14760
CLYCelly_2636
CBATM666_12270
KDIKrodi_2766
DDOI597_2181(wbpI)
MLTVC82_2497
NDODDD_3540(fnlC)
POBLPB03_07075
MYRMYRA21_3292
TDIAUW17_02395
MESQC7H62_1056
MARXINR76_09915(wecB)
SINHLS482_11760(wecB)
ASAGFGM00_01230
ELZFCS00_14715
CIHATE47_11260
CHHA0O34_14040
CIOCEQ15_13460
CHRYCEY12_09715
CHRZCO230_02270
CARHEGY05_16405
CSHAEG350_15230
CNKEG343_08465
CJTEG359_09450
CILEG358_16290
CGLENCTC11432_02308(mnaA)
CTAINCTC12078_01303(mnaA)
CTAK4412677_01079(mnaA)
CSALNBC122_00351(wbpI_1) NBC122_02874(wbpI_2)
CBPEB354_02700
CJGNCTC13459_02734(mnaA)
CANTNCTC13489_01521(mnaA)
KHIEG338_06415
CNREB819_08325
ESTEHNV03_12275(wecB)
BBAUAEM51_06825
CLZBIU88_00475
PPHPpha_0560
THERY592_04245
FPEFerpe_0106
FIANA23_00525
DTNDTL3_0981
MINFMESINF_0678
CABYCabys_3396
NMVNITMOv2_3487
BBGWUT28_C0001G0406
MEFMSWH1_3012
NCLC5F47_00705
 » show all
Reference
1  [PMID:12464616]
  Authors
Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS
  Title
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
  Journal
J Biol Chem 278:3615-27 (2003)
DOI:10.1074/jbc.M203867200
Reference
2  [PMID:15778500]
  Authors
Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS
  Title
Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
  Journal
J Biol Chem 280:19535-42 (2005)
DOI:10.1074/jbc.M500612200
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.28
IUBMB Enzyme Nomenclature: 5.1.3.28
ExPASy - ENZYME nomenclature database: 5.1.3.28
BRENDA, the Enzyme Database: 5.1.3.28

DBGET integrated database retrieval system