KEGG   ENZYME: 5.1.3.31Help
Entry
EC 5.1.3.31                 Enzyme                                 

Name
D-tagatose 3-epimerase;
L-ribulose 3-epimerase;
ketose 3-epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
D-tagatose 3-epimerase
Reaction(IUBMB)
(1) D-tagatose = D-sorbose [RN:R10818];
(2) D-psicose = D-fructose [RN:R10817]
Reaction(KEGG)
Substrate
D-tagatose [CPD:C00795];
D-psicose [CPD:C06468]
Product
D-sorbose [CPD:C00764];
D-fructose [CPD:C00095]
Comment
The enzymes isolated from the bacteria Pseudomonas cichorii [2], Pseudomonas sp. ST-24 [1], Rhodobacter sphaeroides [3] and Mesorhizobium loti [4] catalyse the epimerization of various ketoses at the C-3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose. The specificity depends on the species. The enzymes from Pseudomonas cichorii and Rhodobacter sphaeroides require Mn2+ [2,3].
History
EC 5.1.3.31 created 2014
Orthology
K18910  D-psicose/D-tagatose/L-ribulose 3-epimerase
Genes
VNI: VIBNI_B2134
VSH: BSZ05_18720
CEB: B0D95_16695
HJA: BST95_04425 BST95_12590
MMT: Metme_2524
MDH: AYM39_05640
MKO: MKLM6_1146
HAF: C8233_04545
CMAI: BFX80_10770
BCEN: DM39_5554
BMU: Bmul_3563
BMK: DM80_4951
BSTG: WT74_30375
BGU: KS03_4299
BGO: BM43_5843
VEI: Veis_3271
DAC: Daci_0782
HYB: Q5W_00980
ATU: Atu4748 Atu4750(dpe)
MMED: Mame_03157
HDI: HDIA_0684
RSP: RSP_3671
RDE: RD1_3873
DSH: Dshi_0533
CLS: CXIVA_15900(IolE)
CCE: Ccel_0941
ROB: CK5_09670
SBH: SBI_01788
SALB: XNR_0898
AAU: AAur_1891
SERJ: SGUI_0940
BLIN: BLSMQ_0068
MPH: MLP_04780
NDA: Ndas_4059
NAL: B005_1215
NML: Namu_1536
ACTI: UA75_21195
ACAD: UA74_20700
SNA: Snas_4652
SYY: SYNGTS_1069(sll1304)
SYT: SYNGTI_1069(sll1304)
SYS: SYNPCCN_1068(sll1304)
SYQ: SYNPCCP_1068(sll1304)
CAA: Caka_0707
RBA: RB11728
PSL: Psta_0700
PLM: Plim_0391
TTF: THTE_3776
IPA: Isop_0568
SACI: Sinac_5698
SLI: Slin_0509
FAE: FAES_1761
FJO: Fjoh_4045
MARM: YQ22_00835
 » show all
Taxonomy
Reference
1
  Authors
Itoh, H., Okaya, H., Khan, A. R., Tajima, S., Hayakawa, S., Izumori, K.
  Title
Purification and characterization of D-tagatose 3-epimerase from Pseudomonas sp. ST-24.
  Journal
Biosci Biotechnol Biochem 58:2168-2171 (1994)
Reference
2  [PMID:17936787]
  Authors
Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S
  Title
Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.
  Journal
J Mol Biol 374:443-53 (2007)
DOI:10.1016/j.jmb.2007.09.033
Reference
3  [PMID:19205890]
  Authors
Zhang L, Mu W, Jiang B, Zhang T
  Title
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.
  Journal
Biotechnol Lett 31:857-62 (2009)
DOI:10.1007/s10529-009-9942-3
  Sequence
Reference
4  [PMID:23470755]
  Authors
Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K
  Title
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.
  Journal
Biosci Biotechnol Biochem 77:511-5 (2013)
DOI:10.1271/bbb.120745
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.31
IUBMB Enzyme Nomenclature: 5.1.3.31
ExPASy - ENZYME nomenclature database: 5.1.3.31
BRENDA, the Enzyme Database: 5.1.3.31

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