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Entry
EC 5.1.3.41                 Enzyme                                 

Name
fructoselysine 3-epimerase;
frlC (gene name)
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
D-fructosyl-L-lysine 3-epimerase
Reaction(IUBMB)
N6-(D-fructosyl)-L-lysine = N6-(D-psicosyl)-L-lysine [RN:R11720]
Reaction(KEGG)
Substrate
N6-(D-fructosyl)-L-lysine [CPD:C16488]
Product
N6-(D-psicosyl)-L-lysine [CPD:C21616]
Comment
The enzyme, characterized from the bacterium Escherichia coli, is involved in the catabolism of fructoseamines, amino acid sugar complexes that are formed non-enzymically.
History
EC 5.1.3.41 created 2017
Orthology
K10709  fructoselysine 3-epimerase
Genes
ECO: b4474(frlC)
ECJ: JW5699(frlC)
ECD: ECDH10B_3548(frlC)
EBW: BWG_3064(frlC)
ECOK: ECMDS42_2819(frlC)
ECE: Z4733
ECS: ECs4223
ECF: ECH74115_4684
ETW: ECSP_4330(frlC)
ELX: CDCO157_3964
EOI: ECO111_4182(frlC)
EOJ: ECO26_4461(frlC)
EOH: ECO103_4091(frlC)
ESL: O3K_02205
ESO: O3O_23445
ESM: O3M_02250
ECK: EC55989_3778(frlC)
EOK: G2583_4078(frlC)
ELH: ETEC_3623
ECY: ECSE_3634
ECR: ECIAI1_3511(frlC)
EBR: ECB_03223(frlC)
EBL: ECD_03223(frlC)
EBE: B21_03175(frlC)
EBD: ECBD_0376
ELO: EC042_3634(frlC)
EKF: KO11_05935(frlC)
EDJ: ECDH1ME8569_3252(frlC)
ELW: ECW_m3628(frlC)
ELL: WFL_17720(frlC)
ELP: P12B_c3471(frlC)
SFL: SF3391(yhfP)
SFX: S4371(yhfP)
SFV: SFV_3378(yhfP)
SFE: SFxv_3702(frlC)
SFN: SFy_4818
SFS: SFyv_4893
SSN: SSON_3504(yhfP)
SBO: SBO_3360(yhfP)
ESA: ESA_04363
CSK: ES15_0290(frlC)
CTU: CTU_38890(frlC)
METY: MRY16398_04140(frlC)
AHN: NCTC12129_00402(frlC)
SMD: Smed_5464
RSP: RSP_3944(frlC)
RCP: RCAP_rcp00008(frlC)
PPM: PPSC2_02760(frlC1) PPSC2_08145(frlC3)
PPO: PPM_0493(frlC1) PPM_1543(frlC3)
PPQ: PPSQR21_005260(iolE)
PRI: PRIO_4889
BPRL: CL2_05420
ERH: ERH_1397
OLS: Olsu_1404
 » show all
Taxonomy
Reference
1  [PMID:14641112]
  Authors
Wiame E, Van Schaftingen E
  Title
Fructoselysine 3-epimerase, an enzyme involved in the metabolism of the unusual Amadori compound psicoselysine in Escherichia coli.
  Journal
Biochem J 378:1047-52 (2004)
DOI:10.1042/BJ20031527
  Sequence
[eco:b4474]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.41
IUBMB Enzyme Nomenclature: 5.1.3.41
ExPASy - ENZYME nomenclature database: 5.1.3.41
BRENDA, the Enzyme Database: 5.1.3.41

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