Entry
Name
D-glucosamine-6-phosphate 4-epimerase;
ST2245 (locus name)
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
D-glucosamine 6-phosphate 4-epimerase
Reaction(IUBMB)
D-glucosamine 6-phosphate = D-galactosamine 6-phosphate [RN:
R12220 ]
Reaction(KEGG)
Substrate
D-glucosamine 6-phosphate [CPD:
C00352 ]
Product
D-galactosamine 6-phosphate [CPD:
C06377 ]
Comment
The enzyme, characterized from the archaeon Sulfolobus tokodaii, participates in a pathway for the biosynthesis of UDP-N-acetyl-alpha-D-galactosamine.
History
EC 5.1.3.42 created 2018
Pathway
ec00520 Amino sugar and nucleotide sugar metabolism
Reference
Authors
Dadashipour M, Iwamoto M, Hossain MM, Akutsu JI, Zhang Z, Kawarabayasi Y
Title
Identification of a Direct Biosynthetic Pathway for UDP-N-Acetylgalactosamine from Glucosamine-6-Phosphate in Thermophilic Crenarchaeon Sulfolobus tokodaii.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.42
ExPASy - ENZYME nomenclature database: 5.1.3.42