KEGG ENZYME: 5.1.3.8

ENZYME: 5.1.3.8

Entry

EC 5.1.3.8                  Enzyme

Name

N-acylglucosamine 2-epimerase;
acylglucosamine 2-epimerase;
N-acetylglucosamine 2-epimerase

Class

Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives

Sysname

N-acyl-D-glucosamine 2-epimerase

Reaction(IUBMB)

N-acyl-D-glucosamine = N-acyl-D-mannosamine [RN:R02652]

Reaction(KEGG)

R02652 > R01207

Substrate

N-acyl-D-glucosamine [CPD:C03000]

Product

N-acyl-D-mannosamine [CPD:C00625]

Comment

Requires catalytic amounts of ATP.

History

EC 5.1.3.8 created 1972

Pathway

ec00520

Amino sugar and nucleotide sugar metabolism

ec01100

Metabolic pathways

Orthology

K01787

N-acylglucosamine 2-epimerase

Genes

HSA:	5973(RENBP)

PTR:	741507(RENBP)

PPS:	100969311(RENBP)

GGO:	101140414(RENBP)

PON:	100939320(RENBP)

PPYG:

129025365(RENBP)

NLE:	100587483(RENBP)

HMH:	116811229(RENBP)

SSYN:

129475756(RENBP)

MCC:	698140(RENBP)

MCF:	102133154(RENBP)

MTHB:

126945476

MNI:	105467313(RENBP)

CSAB:

103232810(RENBP)

CATY:

105598720(RENBP)

PANU:

100137256(RENBP)

TGE:	112615085(RENBP)

MLEU:

105555364(RENBP)

RRO:	104661191(RENBP)

TFN:	117063333(RENBP)

PTEH:

111532460(RENBP)

CANG:

105521652(RENBP)

CJC:	100413189(RENBP)

SBQ:	101052023(RENBP)

CIMI:

108294736

ANAN:

105707086(RENBP)

CSYR:

103274077(RENBP)

MMUR:

105867314(RENBP)

LCAT:

123628471

PCOQ:

105824541(RENBP)

OGA:	100951525(RENBP)

MMU:	19703(Renbp)

MCAL:

110286726(Renbp)

MPAH:

110313667(Renbp)

RNO:	81759(Renbp)

MCOC:

116086087(Renbp)

ANU:	117694149(Renbp)

MUN:	110542610 132649837(Renbp) 132649839 132650049

CGE:	100753186 100768545(Renbp)

MAUA:

101825656

PROB:

127217349(Renbp) 127230438

PLEU:

114694133 114706216

MORG:

121437172 121440298

MFOT:

126490238

AAMP:

119804716

NGI:	103731209(Renbp)

HGL:	101726189(Renbp)

CPOC:

100735699(Renbp)

CCAN:

109701897(Renbp)

DORD:

106000151(Renbp)

DSP:

122097020

PLOP:

125344264

NCAR:

124972079

MMMA:

107160281

OCU:

103345585

OPI:

101533545

TUP:	102501530(RENBP)

GVR:	103595091(RENBP)

CFA:	612532(RENBP)

CLUD:

112668375

VVP:	112911497(RENBP)

VLG:

121483335

NPO:	129518900(RENBP)

AML:	100463776(RENBP)

UMR:

103679693

UAR:

123786231

ELK:

111139195

LLV:

125091310

MPUF:

101685706(RENBP)

MNP:	132007717(RENBP)

MLK:	131820842(RENBP)

NVS:

122896748

ORO:	101381597(RENBP)

EJU:	114201604(RENBP)

ZCA:

113930554

MLX:	118014760(RENBP)

NSU:

110577715

LWW:	102726912(RENBP)

FCA:	101089754(RENBP)

PYU:

121025034

PCOO:

112870848(RENBP)

PBG:

122477509

PVIV:

125159276(RENBP)

LRUF:

124525837

PTG:	102971157(RENBP)

PPAD:

109259843(RENBP)

PUC:

125932076

AJU:

106989723

HHV:

120221707

BTA:	516214(RENBP)

BOM:	102276973(RENBP)

BBUB:

102408230

BBIS:

104981398(RENBP)

CHX:	102173084(RENBP)

OAS:	101107767(RENBP)

BTAX:

128070087(RENBP)

ODA:

120881822

CCAD:

122435182

MBEZ:

129534791(RENBP)

SSC:	396934(RENBP)

CFR:	102503931(RENBP)

CBAI:

105076071(RENBP)

CDK:	105098713(RENBP)

VPC:	102545278(RENBP)

BACU:

102997814(RENBP)

BMUS:

118888840

LVE:	103071115(RENBP)

OOR:	101280386(RENBP)

DLE:	111170597(RENBP)

PCAD:

102980391(RENBP)

PSIU:

116747008(RENBP) 116747786

NASI:

112406761(RENBP)

ECB:	100059102(RENBP)

EAI:

106825628

MYB:	102259001(RENBP)

MYD:	102758001(RENBP)

MMYO:

118653876

MLF:	102420525(RENBP)

MDT:	132224749(RENBP)

PKL:

118714715

EFUS:

103302247(RENBP)

MNA:	107538792(RENBP)

DRO:	112296330(RENBP)

SHON:

118994301

AJM:

119053496

PDIC:

114505727

PHAS:

123823115

MMF:

118635776

PPAM:

129074337(RENBP)

HAI:	109394347(RENBP)

RFQ:	117026928(RENBP)

PALE:

102893908(RENBP)

PGIG:

120605893

PVP:	105302525(RENBP)

RAY:	107517748(RENBP)

MJV:

108407469

TOD:	119245800(RENBP)

SARA:

101548116(RENBP)

SETR:

125999487(RENBP) 126018398

LAV:	100676746(RENBP)

TMU:

101342655

ETF:

101663062

DNM:	101411960(RENBP)

MDO:	100029417(RENBP)

GAS:

123254064

SHR:	100923111(RENBP)

AFZ:

127542589

PCW:	110201558(RENBP)

TVP:

118833062

OAA:

100082474

PCOC:

116241383(RENBP)

LSR:	110481612(RENBP)

PMOA:

120505128

OTC:

121338785

HRT:	120748055(RENBP)

AROW:

112962727(RENBP)

ASN:	102377988(RENBP)

AMJ:	102577339(RENBP)

CCAY:

125628375

DCC:

119847525

CABI:

116833450(RENBP)

MRV:

120388954

ACS:	100563588(renbp)

ASAO:

132767842(RENBP)

PVT:	110078635(RENBP)

SUND:

121924307

PBI:	103066885(RENBP)

PMUR:

107284222(RENBP)

CTIG:

120301424

TSR:	106555409(RENBP)

PGUT:

117675514(RENBP)

APRI:

131192864(RENBP)

PTEX:

113443293(RENBP)

NSS:	113417697(RENBP)

VKO:

123029977

PMUA:

114587586(RENBP)

PRAF:

128405228(RENBP)

ZVI:	118097470(RENBP)

HCG:	128341927(RENBP)

GJA:	107118708(RENBP)

EMC:	129346017(RENBP)

XLA:	734433(renbp.L)

XTR:	100127793(renbp)

NPR:	108784476(RENBP)

RTEM:

120913202

BBUF:

120977689

BGAR:

122946028

MUO:	115462409 115463517

GSH:	117349145(RENBP)

DRE:	791728(renbp)

SRX:	107725049 107747208

SANH:

107683888 107702837

SGH:	107550931(renbp) 107570513

CCAR:

109054874 109099988

CAUA:

113107379(renbp)

CGIB:

127963008

PTET:

122350099

LROH:

127169459(renbp)

OMC:	131545508(renbp)

PPRM:

120479881

RKG:	130081926(renbp)

MAMB:

125280214

CIDE:

127517272 127517302

CERY:

137026579(renbp)

MASI:

127414666 127424547

TROS:

130567801(renbp)

TDW:	130440200(renbp)

MANU:

129414616(renbp)

IPU:

108265476

IFU:	128607539(renbp)

PHYP:

113533494(renbp)

SMEO:

124399509

TFD:

113656096

TVC:	132853409(renbp)

TRN:	134318376(renbp)

AMEX:

103039529

CMAO:

118813628

EEE:	113578752(renbp)

CHAR:

105893666

TRU:	101077243(renbp)

TNG:	GSTEN00005899G001

LCO:	104917662(renbp)

NCC:	104954841(renbp)

TBEN:

117494683(renbp)

CGOB:

115020726 115021457

PGEO:

117449659(renbp)

GACU:

117547726(renbp)

EMAC:

134870154(renbp)

ELY:	117257892(renbp)

EFO:

125892012

PLEP:

121947022

SLUC:

116058558

ECRA:

117948261(renbp)

ESP:	116693003(renbp)

PFLV:

114559088(renbp)

GAT:

120829389

PPUG:

119222618

AFB:	129099992(renbp)

CLUM:

117734064(renbp)

PSWI:

130199958(renbp)

MSAM:

119905973

SCHU:

122883755

CUD:

121516981

ALAT:

119022820

ASTR:

137602746(renbp)

MZE:	101483065(renbp)

ONL:	100697984(renbp)

OAU:

116326139

OLA:	101162760(renbp)

OML:

112158918

CSAI:

133456309(renbp)

XMA:	102221319(renbp)

XCO:	114142219(renbp)

XHE:	116721295(renbp)

PRET:

103467070(renbp)

PFOR:

103155314(renbp)

PLAI:

106949564(renbp)

PMEI:

106924482(renbp)

GAF:

122846951

PPRL:

129371860(renbp)

CVG:	107100385(renbp)

CTUL:

119799176

GMU:

124870103

NFU:	107391382(renbp)

KMR:

108229113

ALIM:

106529342(renbp)

NWH:

119417355

AOCE:

111574445(renbp)

MCEP:

125020807

CSEM:

103384874(renbp)

POV:	109639668(renbp)

SSEN:

122777151

HHIP:

117765150(renbp)

HSP:

118110832

PPLT:

128442664(renbp)

SMAU:

118317087

LCF:

108900499

SDU:	111233781(renbp)

SLAL:

111658852(renbp)

XGL:

120804423

HCQ:	109528347(renbp)

SSCV:

125987736

SBIA:

133512061(renbp)

PEE:	133408443(renbp)

PTAO:

133486850(renbp)

BPEC:

110159391(renbp)

MALB:

109952549(renbp)

BSPL:

114858694(renbp)

SJO:	128356735(renbp)

SASA:

106566966(renbp) 106566967

STRU:

115168994(renbp)

OTW:

112221623

OMY:

110491897

OGO:

124046154

ONE:	115102628(renbp)

OKI:	109869234(renbp)

OKE:	118360182(renbp)

SALP:

111977046(renbp)

SNH:

120060610

CCLU:

121545961

ELS:	105013813(renbp)

SFM:	108918511(renbp)

PKI:	111857085(renbp)

AANG:

118211276(renbp)

LOC:	102691182(renbp)

PSPA:

121329373

ARUT:

117404243(renbp)

PSEX:

120543374

LCM:	102364490(RENBP)

CPLA:

122546588

LERI:

129694062(renbp)

PMRN:

116951135(RENBP)

LRJ:	133356399(RENBP)

BFO:

118416823

BBEL:

109472489

CIN:

100186287

SPU:

579325

LPIC:

129257394

APLC:

110974162

ARUN:

117304142 117307136

AJC:

117115669

SKO:

102801223

TCF:

131884670

LGI:	LOTGIDRAFT_236307

PVUL:

126827561 126827562

PCAN:

112572237

BGT:

106080149

GAE:

121368897

HRF:

124144264

HRJ:

124270211

CRG:

105342548

CANU:

128159011

CVN:

111107413

OED:

125653332

MYI:

110460959

PMAX:

117331434

MCAF:

127710573

MMER:

123541267

RPHI:

132725921

DPOL:

127851067 127851068 127851070 127851317 127851788

MAEA:

128206683

OBI:

106878928

OSN:

115219033

LJP:

135470364

LAK:	106153034 106178935

LLON:

135487038

NVE:

5509284

EPA:

110241023

ATEN:

116290351

ADF:

107358492

AMIL:

114958877

PDAM:

113665524

SPIS:

111344682

DGT:	114522766 114536549

RES:

135686707

AQU:

100631532

BIF:	N288_22900

FEC:	QNH15_23705

PNP:	IJ22_49130

POW:	IJ21_26430

PAUN:

MJA45_08045

PKP:	SK3146_04937(ce)

ACUR:

JZ785_21050

CLO:	HMPREF0868_0510

CSS:	Cst_c27550

CSD:

Clst_2641

FPLA:

A4U99_07970

LASA:

L9O85_06330

BPRO:

PMF13cell1_00841

BCOC:

BLCOC_46910

VGU:	HYG85_07185

FBS:	N510_002175(ce)

EYY:	EGYY_09960

EGD:	GS424_012275

GPA:

GPA_21700

EBZ:	J7S26_05695

ARM:

ART_1278

ARTH:

C3B78_17210

BCV:

Bcav_3354

GEZ:	FE251_12395

HALT:

IM660_02210

RHAL:

LQF10_01965

PRV:	G7070_10385

PROP:

QQ658_09215

ACTQ:

OG417_48335

NFS:	OIE67_14485

PHH:	AFB00_13425

SYN:

slr1975

SYZ:	MYO_116500

SYY:	SYNGTS_1635(slr1975)

SYT:	SYNGTI_1635(slr1975)

SYS:	SYNPCCN_1634(slr1975)

SYQ:	SYNPCCP_1634(slr1975)

SYJ:	D082_06900

SYO:	C7I86_08485

SYNH:

HTZ78_15510

DSL:	Dacsa_1969

WNA:	KA717_20230

CMP:	Cha6605_2911

AMR:

AM1_3842

ACAM:

HRE53_15170

LEN:	LEP3755_31110

LBO:	LBWT_48650

HHG:	XM38_041210(age)

CHON:

NIES4102_14750

HAO:	PCC7418_1017

ENN:	FRE64_02305

ANA:

all3695

NPU:	Npun_R2950

NOS:	Nos7107_4585

NOP:	Nos7524_3553

NON:	NOS3756_14750

NFL:	COO91_05296

NOE:	CLI64_25145

NSH:

GXM_04495

NED:	HUN01_14160

NPZ:	ACX27_17560

NLK:	NIES25_16400

NCW:	NIES2107_61190

NCF:	ANSO36C_28710

AVA:

Ava_3567

ANN:	EH233_20615

HBQ:	QI031_28970

CALO:

Cal7507_4683

CALT:

Cal6303_4153

CALN:

NIES2098_47090

CALS:

NIES3974_40030

RIV:	Riv7116_4703

MDP:	NIES3275_64890

FIS:	FIS3754_12520

NSPH:

BDGGKGIB_01820(ce)

AEE:	IM676_11470

TOQ:	HCG51_22625

TTQ:	NIES37_12330

ALAX:

NIES50_07490

SCYT:

SAMD_00370

SCYS:

NIES4073_15830

BSEN:

DP114_17680

BOX:	DP113_17615

NCN:	BZZ01_22845

CTHE:

Chro_4768

PLP:	Ple7327_1751

RRS:	RoseRS_1977

RCA:

Rcas_3784

CAU:

Caur_1104

CHL:	Chy400_1209

ABAO:

BEQ56_03160

KBS:	EPA93_00960

KBB:	ccbrp13_57040

SLOM:

PXH66_07390

ELUT:

CKA38_09990

AAQW:

K1X11_014695 K1X11_023310

OBT:	OPIT5_17225 OPIT5_24490 OPIT5_24620

AMU:

Amuc_1947

AGL:

PYTT_0731

ABIW:

Abiwalacus_24370

AMAK:

J5W79_11195

ROO:	G5S37_01525

LUO:	HHL09_03700

LAMB:

KBB96_01480

LUI:

llg_00200

SOA:	G3M56_010280

RBA:

RB3348

PSL:

Psta_1239

PIR:	VN12_04925(ce)

RUL:	UC8_11640(bfce)

RML:	FF011L_46610

ROL:	CA51_38040(bfce)

AHEL:

Q31a_39320(ce_2)

BREM:

PSR63_07625 PSR63_23790

RLC:	K227x_40430(ce)

SMAM:

Mal15_12510(ce) Mal15_18460(bfce)

SNEP:

Enr13x_03810(bfce)

AMUC:

Pan181_32040(ce)

AMOB:

HG15A2_23600(ce) HG15A2_24220

CCOS:

Pan44_54550(ce)

TIM:	GMBLW1_20230

LRS:	PX52LOC_04969

PCOR:

KS4_00980(ce)

PBU:	L21SP3_02085(ce_1) L21SP3_02096(ce_2)

PBAS:

SMSP2_00896 SMSP2_02131(ce)

ALUS:

STSP2_01849(bfce)

HBS:	IPV69_21905

TAER:

GT409_12085

VBC:	C5Q97_03970 C5Q97_10725

TBE:	Trebr_1443

TPAV:

HRQ91_06770

TSK:	HRI97_01500

SSM:	Spirs_0731 Spirs_3621

SLR:	L21SP2_0524

SBU:	SpiBuddy_0432 SpiBuddy_1040

SGP:	SpiGrapes_1515

SASS:

MUG09_02345 MUG09_05840

BHC:	JFL75_06585 JFL75_18930

BHY:	BHWA1_01994

BHD:	BHYOB78_06160

BRM:

Bmur_1366

BPO:	BP951000_0920

BPJ:	B2904_orf444

BPIP:

BPP43_10475

BPW:

WESB_2242

BIP:

Bint_2712

BHP:	BHAMNSH16_08515

BTH:	BT_0437 BT_0453 BT_3605

BTHO:

Btheta7330_02908(ce_1) Btheta7330_02922(ce_2) Btheta7330_02939(ce_3) Btheta7330_04680(ce_4)

BFR:

BF1707

BFS:	BF9343_1632 BF9343_3946

BFG:	BF638R_1717 BF638R_4099

BFB:	VU15_07245

BHL:	Bache_2788

BXY:	BXY_03750 BXY_42550

BOA:	Bovatus_00289(ce_1) Bovatus_00309(ce_2) Bovatus_00651(ce_3)

BCEL:

BcellWH2_00746(ce)

BCAC:

CGC64_11150

BCAE:

A4V03_00135 A4V03_06775 A4V03_06860

BZG:	C4H11_06745 C4H11_08875

BHF:	C3V43_10320

BIS:	DXK01_019020

BUN:	Bun01g_22680

BEG:	INE88_03330

BSTE:

K6V31_08570

BFE:	K6V30_06515 K6V30_18385 K6V30_18485

BNO:	K8P02_05280

BHUM:

JXR92_009835

BFC:	BacF7301_16380 BacF7301_17655

BSAL:

K6V25_12150

BFIN:

BFINE_42480 BFINE_42810

BVU:

BVU_4118

BDO:	EL88_15485

BDH:	GV66_21895

PCOP:

I6J50_17250

PORP:

J4862_06490

PBT:	ING2E5B_2381(renBP)

PMUC:

ING2E5A_0837(Renbp)

PET:	PEIBARAKI_6549

PSAC:

PSM36_3089(renBP)

PROJ:

KDN43_02185

PDI:

BDI_2942

PARC:

CI960_20945

PMER:

INE87_02674(ce)

PGOL:

K6V26_22085

PJO:	LK449_16305

PFAI:

NXY11_20995

TFO:

BFO_2203

PARY:

A4V02_00020

PII:	NF347_09360

COPR:

Cop2CBH44_18940

CFAS:

Cfast33896_08710

PMZ:	HMPREF0659_A5875

PDN:	HMPREF9137_1366

PDT:	Prede_1037

PRO:	HMPREF0669_00715

PFUS:

ADJ77_02290

PJE:	CRM71_04670

PMUF:

J4864_02770

PVF:	J5A55_10690

PSCJ:

J4856_09460

POC:	NCTC13071_00097

PEO:	AS203_02630

PBUC:

LK429_01080

ALQ:	C7Y71_003825

AFD:

Alfi_2074

ASH:	AL1_14580 AL1_27220

AOK:	A3BBH6_15690

ADA:	A5CPEGH6_12150 A5CPEGH6_15510

ASEN:

NQ519_03880

RBC:	BN938_2365

BACC:

BRDCF_p378

DORI:

FH5T_13870

ANF:

AQPE_4368

CHIT:

FW415_10755

COY:	HF329_22505

CHOR:

MKQ68_17600

CPOL:

WJU16_08330

NKO:	Niako_5240

NSO:	NIASO_04165

NIA:	A8C56_20440

FLA:	SY85_05280

FGG:	FSB75_00740

ARK:	D6B99_12630

AGI:	FSB73_06765

ATEE:

K9M52_02700

PSEG:

D3H65_17045

PGO:	FSB84_22875

FLS:	GLV81_17595

LACS:

H4075_05120 H4075_08750

FLV:	KJS94_14085

SEDT:

TEGAF0_25110

HHY:	Halhy_5308

PHE:	Phep_2987 Phep_3251

PEP:	AQ505_14390

PGS:	CPT03_08015

PROE:

H9L23_05820

PEX:	IZT61_04580

PGJ:	QG516_01225

PSN:	Pedsa_0026 Pedsa_0685

SHG:	Sph21_0108

SHT:	KO02_01175

SPHN:

BV902_06640

SMIZ:

4412673_03725

SPSC:

E2P86_07220 E2P86_12365 E2P86_16350 E2P86_17085

SPHZ:

E3D81_09370

SPHE:

GFH32_00770 GFH32_09555 GFH32_12285 GFH32_12445

STHA:

NCTC11429_02007 NCTC11429_02644

SSPI:

I6J01_02360

SMUI:

I6J00_22065

SSIY:

JVX97_10970 JVX97_26630

SFAE:

MUK51_17770

SCN:	Solca_2699

MGOT:

MgSA37_01114(ce_2)

MRUB:

DEO27_011515

SBX:	CA265_04860

CMR:	Cycma_4897

CAMU:

CA2015_4715

BBD:	Belba_3237

EVI:	Echvi_4339

EST:	DN752_04800

EMAI:

KZP23_15215

SLI:	Slin_2630 Slin_5917

SRD:	SD10_23340

SMON:

AWR27_17270

SPIR:

CWM47_27655

SPIK:

EXU85_03135

SPIB:

G8759_00475 G8759_32465

STAE:

HNV11_22465

SRHO:

HH216_07140

SOQ:	LQ777_00725 LQ777_05600

SFOL:

H3H32_33430

SENF:

GJR95_24790 GJR95_32635

DFE:

Dfer_5333

DYC:	NFI80_08215

DFQ:	NFI81_11730

RSI:	Runsl_0397

RUN:	DR864_23755

RUP:	DTQ70_02650

FAE:	FAES_0410 FAES_5032

FIB:	A6C57_25425

HTB:	MTX78_23745

PKO:	PKOR_22925

RUF:	TH63_14515

NIB:	GU926_09100

ASWU:

HUW51_05895

FPF:	DCC35_19515

GRS:	C7S20_18800

FJG:	BB050_03927

FNK:	E1750_00825

FBI:	L0669_22255

FPLU:

NLG42_18060

FAV:	LNP19_09510

FGC:	LNP27_11250

COC:

Coch_2066

CCM:	Ccan_04780

COL:	AM608_02865

CHG:	AXF12_07715

CAPN:

CBG49_11680

CLK:	CGC53_09510

CSPU:

CGC55_13475

CCYN:

CGC48_07790

CAPH:

CGC49_04870

CSTO:

CGC58_04390

CAPQ:

CGC52_04650

CAPF:

FOC45_03355

CAPO:

HW278_00535

FBC:	FB2170_03930

MART:

BTR34_05125

MARE:

EJ994_11920

ZGA:	ZOBELLIA_1044

POA:	CW731_00465

TMAR:

MARIT_2682(age)

SALT:

AO058_09955

AALG:

AREALGSMS7_02036(ce)

OCI:	FEZ18_00910

CAGG:

HYG79_05255

MRS:	Murru_0549 Murru_3347

ZSP:	MQE36_11645

FBE:	FF125_09260

HWS:	RNZ46_12470

ORH:	Ornrh_0309

ORI:	Q785_01680

OHM:	MSHRCOH1_05940

ELT:	FGE20_11220

RLO:	GQ464_017030

SCHV:

BRCON_2646

LOB:	NEF87_000282

» show all

Reference

1 [PMID:14285488]

Authors

GHOSH S, ROSEMAN S.

Title

THE SIALIC ACIDS. V. N-ACYL-D-GLUCOSAMINE 2-EPIMERASE.

Journal

J Biol Chem 240:1531-6 (1965)

Other DBs

ExplorEnz - The Enzyme Database:

5.1.3.8

IUBMB Enzyme Nomenclature:

5.1.3.8

ExPASy - ENZYME nomenclature database:

5.1.3.8

BRENDA, the Enzyme Database:

5.1.3.8

CAS:	37318-34-6

DBGET integrated database retrieval system