KEGG   ENZYME: 5.3.1.29Help
Entry
EC 5.3.1.29                 Enzyme                                 

Name
ribose 1,5-bisphosphate isomerase;
R15P isomerase;
ribulose 1,5-bisphosphate synthase;
RuBP synthase
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds
BRITE hierarchy
Sysname
alpha-D-ribose 1,5-bisphosphate aldose-ketose-isomerase
Reaction(IUBMB)
alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate [RN:R10555]
Reaction(KEGG)
Substrate
alpha-D-ribose 1,5-bisphosphate [CPD:C01151]
Product
D-ribulose 1,5-bisphosphate [CPD:C01182]
Comment
This archaeal enzyme is involved in AMP metabolism and CO2 fixation through type III RubisCO enzymes. The enzyme is activated by cAMP [2].
History
EC 5.3.1.29 created 2013
Orthology
K18237  ribose 1,5-bisphosphate isomerase
Genes
ABAW: D5400_18205
VNE: CFK40_04125
EAV: EH197_23085
ERB: A4V01_03310 A4V01_03935
BPW: WESB_1267(gcn3)
SRB: P148_SR1C001G0163
MJA: MJ_0122
MFE: Mefer_1167
MVU: Metvu_0771
MFS: MFS40622_0999
MAE: Maeo_0673
AFU: AF_2037
FPL: Ferp_2476
GAC: GACE_2136
GAH: GAH_00545
MARC: AR505_1643
ABI: Aboo_0331
PHO: PH0208(PH0208)
PAB: PAB2402
PFU: PF0122
PFI: PFC_07590
PYN: PNA2_0724
PYS: Py04_0275
TKO: TK0185
TON: TON_1296
TGA: TGAM_1633
TSI: TSIB_0548
THE: GQS_08985
THA: TAM4_1574
THM: CL1_1398
TLT: OCC_04330
THS: TES1_1328
TNU: BD01_1733
TEU: TEU_00610
PPAC: PAP_04815
MAC: MA_0379(eif2B2)
MBAR: MSBR2_2119
MBAK: MSBR3_2069
MMA: MM_1606
MMAC: MSMAC_3082
METM: MSMTP_2960
MTHE: MSTHC_1125
MTHR: MSTHT_2157
MHOR: MSHOH_3785
MBU: Mbur_1938
MMET: MCMEM_0162
MMH: Mmah_0172
MPY: Mpsy_1650
MTP: Mthe_1262
MCJ: MCON_0206
MHI: Mhar_2272
MHU: Mhun_2314
MLA: Mlab_0557
MEMA: MMAB1_2076
MPI: Mpet_0507
MBN: Mboo_2432
MPL: Mpal_0257
MPD: MCP_2142
RCI: RRC408(eif2b2)
HAL: VNG_1853G(eif2ba)
HSL: OE_3610R
HHB: Hhub_3205
HALH: HTSR_1864
HHSR: HSR6_1933
NPH: NP_3202A
HTI: HTIA_1280
HMU: Hmuk_2762
HVO: HVO_0966
HME: HFX_0963
HLA: Hlac_2269
HTU: Htur_0571
NMG: Nmag_2966
NAT: NJ7G_4171
SMR: Smar_1357
DKA: DKAM_0459
TAG: Tagg_0677
HBU: Hbut_0498
TPE: Tpen_0384
 » show all
Taxonomy
Reference
1  [PMID:17303759]
  Authors
Sato T, Atomi H, Imanaka T
  Title
Archaeal type III RuBisCOs function in a pathway for AMP metabolism.
  Journal
Science 315:1003-6 (2007)
DOI:10.1126/science.1135999
  Sequence
[tko:TK0185]
Reference
2  [PMID:23065974]
  Authors
Aono R, Sato T, Yano A, Yoshida S, Nishitani Y, Miki K, Imanaka T, Atomi H
  Title
Enzymatic characterization of AMP phosphorylase and ribose-1,5-bisphosphate isomerase functioning in an archaeal AMP metabolic pathway.
  Journal
J Bacteriol 194:6847-55 (2012)
DOI:10.1128/JB.01335-12
  Sequence
[tko:TK0185]
Reference
3  [PMID:22511789]
  Authors
Nakamura A, Fujihashi M, Aono R, Sato T, Nishiba Y, Yoshida S, Yano A, Atomi H, Imanaka T, Miki K
  Title
Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1.
  Journal
J Biol Chem 287:20784-96 (2012)
DOI:10.1074/jbc.M112.349423
  Sequence
[tko:TK0185]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.1.29
IUBMB Enzyme Nomenclature: 5.3.1.29
ExPASy - ENZYME nomenclature database: 5.3.1.29
BRENDA, the Enzyme Database: 5.3.1.29

DBGET integrated database retrieval system