KEGG   ENZYME: 5.3.1.33
Entry
EC 5.3.1.33                 Enzyme                                 

Name
L-erythrulose 1-phosphate isomerase;
eryH (gene name)
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds
Sysname
L-erythrulose-1-phosphate isomerase
Reaction(IUBMB)
L-erythrulose 1-phosphate = D-erythrulose 4-phosphate [RN:R11332]
Reaction(KEGG)
R11332
Substrate
L-erythrulose 1-phosphate [CPD:C03394]
Product
D-erythrulose 4-phosphate [CPD:C03604]
Comment
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.
History
EC 5.3.1.33 created 2016
Orthology
K21910  L-erythrulose 1-phosphate isomerase
Genes
KPU: KP1_2114
KPP: A79E_3110
KPZ: KPNIH27_09450
KPV: KPNIH29_09995
KPY: KPNIH31_09900
KPT: VK055_1343(tpiA)
KPO: KPN2242_08665(tpiA)
KPR: KPR_2161
KPI: D364_05810
KPX: PMK1_03459(pgk_tpi)
KPNK: BN49_2207
KVA: Kvar_3260
KPE: KPK_3433(tpiB)
KOX: KOX_17440(tpiA)
KOE: A225_2341
KOY: J415_20100(tpiA)
EAR: CCG30620
ROR: RORB6_09060(tpiA)
RTG: NCTC13098_01631(tpiA_2)
REE: electrica_03133(pgk_tpi)
PCT: PC1_0752
PEC: W5S_0880
EBI: EbC_33100(tpiA)
MTHI: C7M52_01833(lerI)
LRI: NCTC12151_02838(tpiA_2)
MPRI: MP3633_1150(eryH)
TAU: Tola_3162
BUL: BW21_6134
MLO: mlr7275
MHUA: MCHK_0794
SME: SMc01614(tpiB)
SMX: SM11_chr1033(tpiB)
SMI: BN406_02050(tpiA2)
SMEL: SM2011_c01614(tpiB)
SMER: DU99_12485
SMD: Smed_2150
RHI: NGR_b17390(tpiA) NGR_c06610(tpiA)
SFH: SFHH103_05477(tpiA)
SFD: USDA257_c12890(tpiA1)
SIX: BSY16_3605(tpiA)
SAME: SAMCFNEI73_pC1161(tpiA)
EAD: OV14_3639(tpiA)
ARA: Arad_7454(tpiA)
RET: RHE_PF00040(tpiAf)
REC: RHECIAT_PC0000966(tpiAc)
REL: REMIM1_PF00044(tpiA-2)
REI: IE4771_PA00088(tpiA-2)
RLE: pRL120209(tpiA2)
RLG: Rleg_5328
RTR: RTCIAT899_PC05545(tpiA2)
RHL: LPU83_pLPU83c0537(tpiA1)
RGA: RGR602_PA00072(tpiA-2) RGR602_PC00573(tpiA-3)
RHN: AMJ98_PE00043(tpiA-2)
RPHA: AMC79_PD00973(tpiA-2)
RHX: AMK02_PD00046(tpiA-2)
REZ: AMJ99_PD00043(tpiA-2)
SHZ: shn_16450
BME: BMEII0425
BMEL: DK63_2814
BMI: BMEA_B0848(tpiA)
BMG: BM590_B0833(tpiA)
BMEE: DK62_2584
BMF: BAB2_0367(tpiA-2)
BMB: BruAb2_0363(tpiA-2)
BABO: DK55_2357
BABR: DO74_2777
BABT: DK49_2875
BABB: DK48_2334
BABU: DK53_2367
BABS: DK51_2946
BABC: DO78_2693
BMS: BRA0869(tpiA-2)
BSI: BS1330_II0862(tpiA)
BSF: BSS2_II0823(tpiA)
BSUI: BSSP1_II0814(tpiA)
BSUV: BSPT2_II0812(tpiA)
BSUC: BSSP2_II0823(tpiA)
BMT: BSUIS_B0862(tpiA)
BSZ: DK67_2823
BSV: BSVBI22_B0861(tpiA)
BOV: BOV_A0816(tpiA-1)
BCS: BCAN_B0887(tpiA)
BOL: BCOUA_II0869(tpiA-2)
BCAR: DK60_2560
BCAS: DA85_14630
BMR: BMI_II863(tpiA-2)
BPP: BPI_II925(tpiA-2)
BPV: DK65_2780
BVL: BF3285c2_0393(tpiA)
OAN: Oant_2906
OAH: DR92_3599(tpiA)
MMED: Mame_00691(tpiA_1)
LABT: FIU93_29520(tpiA2)
RDE: RD1_3625(tpiA)
RLI: RLO149_c008400(tpiA1)
OAR: OA238_c42210(tpiA2)
MALG: MALG_04500
MALU: KU6B_05350(tpiA)
PAMO: BAR1_01155
GOX: GOX2217
GOY: GLS_c05720(tpiA1) GLS_c23660(tpiA2)
ABG: Asbog_01354(tim)
RRF: F11_07015(tpiA)
CSCI: HDCHBGLK_01733(pgk_tpi)
ELM: ELI_4298
AWO: Awo_c08970(tpiA1)
TAE: TepiRe1_2385(tpiA)
MSM: MSMEG_6785(tpiA)
MPHL: MPHLCCUG_03580(tpiA_2)
MAUU: NCTC10437_05453(tpiA_2)
MTY: MTOK_43880(lerI)
MARZ: MARA_39720(lerI)
SALU: DC74_6851
SALL: SAZ_35580
ART: Arth_0889
ARR: ARUE_c10600(tpiA1) ARUE_c18620(tpiA2)
ARM: ART_3800
ARX: ARZXY2_2896(tpiA)
AAGI: NCTC2676_1_00196(tpiA_1)
AAU: AAur_1109
BCV: Bcav_1549
PFR: PFREUD_22460(tpi2)
PFRE: RM25_2126
MPH: MLP_03240
PSEA: WY02_03010
PAUT: Pdca_32700
ACTI: UA75_20480
ACAD: UA74_19980
 » show all
Reference
1  [PMID:25453104]
  Authors
Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ
  Title
Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.
  Journal
Proc Natl Acad Sci U S A 111:17815-20 (2014)
DOI:10.1073/pnas.1414622111
  Sequence
[bmf:BAB2_0367]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.1.33
IUBMB Enzyme Nomenclature: 5.3.1.33
ExPASy - ENZYME nomenclature database: 5.3.1.33
BRENDA, the Enzyme Database: 5.3.1.33

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