KEGG   ENZYME: 5.3.2.1
Entry
EC 5.3.2.1                  Enzyme                                 
Name
phenylpyruvate tautomerase;
phenylpyruvic keto-enol isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
Sysname
phenylpyruvate keto---enol-isomerase
Reaction(IUBMB)
keto-phenylpyruvate = enol-phenylpyruvate [RN:R01378]
Reaction(KEGG)
R01378;
(other) R03342
Substrate
keto-phenylpyruvate [CPD:C00166]
Product
enol-phenylpyruvate [CPD:C02763]
Comment
Also acts on other arylpyruvates.
History
EC 5.3.2.1 created 1961
Pathway
ec00350  Tyrosine metabolism
ec00360  Phenylalanine metabolism
ec01100  Metabolic pathways
Orthology
K07253  phenylpyruvate tautomerase
Genes
HSA4282(MIF)
PTR748716(MIF)
PPS100995773(MIF)
GGO101146189(MIF)
PON100438837(MIF)
NLE100581032(MIF)
MCC574298(MIF)
MCF101867092(MIF)
CSAB103223031(MIF)
CATY105599382(MIF)
PANU101018602(MIF)
TGE112632544(MIF)
RRO104667415(MIF)
RBB108540422(MIF)
TFN117079260 117096571(MIF)
PTEH111522035(MIF)
CJC100392923(MIF)
SBQ101038492(MIF)
CSYR103268853(MIF)
MMUR105877819(MIF)
OGA100955945(MIF)
MMU17319(Mif)
MCAL110303158(Mif)
MPAH110326780(Mif)
RNO81683(Mif)
MCOC116074242(Mif)
MUN110558690(Mif)
CGE100766328(Mif)
MAUA101830036 101843132(Mif)
PLEU114696499(Mif)
MORG121435538(Mif) 121441375 121445616 121456074 121461975
NGI103740066(Mif)
HGL101725992(Mif)
CPOC100719548(Mif)
CCAN109690506 109690507
DORD105984214(Mif)
DSP122095928(Mif)
NCAR124990876
OCU100338701(MIF)
OPI101526135 101529650 101531276(MIF)
TUP102489547(MIF)
CFA595146(MIF)
VVP112907528(MIF)
VLG121475616(MIF)
AML100480443(MIF)
UAH113247035(MIF)
UAR123795589(MIF)
ELK111142602
LLV125082326 125106684
MPUF101686697(MIF)
ORO101376805(MIF)
EJU114202343(MIF)
ZCA113913194(MIF) 113917653 113919476 113925114
MLX117999748(MIF)
FCA101090298(MIF)
PYU121023014(MIF)
PBG122470530(MIF)
PTG102955799(MIF)
PPAD109259716(MIF)
AJU106988287(MIF)
HHV120238851(MIF)
BTA280858(MIF)
BIU109570988(MIF)
BBUB102403512(MIF)
CHX108637839(MIF)
OAS780466(MIF)
ODA120871292(MIF)
CCAD122419986(MIF)
SSC397412(MIF)
CFR102518568(MIF)
CBAI105069340(MIF)
CDK105095204(MIF)
VPC102526473(MIF)
BACU103014799
LVE103073098(MIF)
OOR101276106(MIF)
DLE111163021(MIF)
PCAD112064089
PSIU116738986(MIF)
ECB100053618(MIF)
EPZ103541501(MIF)
EAI106847116(MIF)
MMYO118655508(MIF)
MNA107530480(MIF)
PKL118710474(MIF)
DRO112310715(MIF)
SHON119001814(MIF)
AJM119059184(MIF)
PDIC114509758(MIF)
PHAS123806620(MIF)
MMF118640060(MIF)
RFQ117017586(MIF)
PALE102882544(MIF)
PGIG120606863(MIF)
PVP105289341(MIF)
RAY107501246(MIF)
MJV108389703(MIF)
TOD119234174(MIF)
SARA101543991(MIF)
LAV104845409(MIF)
TMU101348711
DNM101445827(MIF)
MDO100014737(MIF)
SHR116420904(MIF)
PCW110201782(MIF)
OAA100081817(MIF)
GGA100857237(MIF)
PCOC116228316(MIF)
MGP100551273(MIF)
CJO107321446(MIF)
NMEL110406243(MIF)
APLA101796948 101804212(MIF)
ACYG106031298 106031440
AFUL116496073 116496358
TGU100190143 100232372
LSR110481382(MIF)
SCAN103818237(MIF) 103818238
PMOA120510230 120510356
OTC121344369 121344427
PRUF121364881 121365145
GFR102039032 102044154
FAB101807041(MIF)
PHI102103863 102111823
PMAJ107211438 107211468
CCAE111936762(MIF)
CCW104688587 104688767
ETL114061538 114061539
ZAB102068711 102068900
FPG101916004(MIF)
FCH102049665(MIF)
CLV102092102 110359817(MIF)
EGZ104130100(MIF)
NNI104011431(MIF)
ACUN113486319(MIF)
TALA104367661
PADL103922605(MIF)
ACHC115346323 115346500
AAM106486278 106486297
AROW112970611 112970650
NPD112945942 112945986
DNE112992800 112992801
ASN102383931
AMJ102572055 102572281(MIF)
CPOO109312817
GGN109290405 109290406
PSS102445441 102446381
CMY102947909 102948142(MIF)
CPIC101933859 101934100
TST117888266 117888271
CABI116837130 116837133
MRV120385975 120385976
PVT110081964(MIF)
SUND121930544(MIF)
PMUR107291844(MIF)
PGUT117677958(MIF)
VKO123030288(MIF)
PMUA114587021(MIF)
ZVI118075925(MIF)
GJA107108555(MIF)
STOW125442358(MIF)
XLA399041(mif.L)
XTR100134996(mif)
NPR108794801(MIF)
RTEM120936628 120936637
BBUF120988737 120991426(MIF)
BGAR122924434 122924435 122934300 122934308
DRE751093(mif)
SRX107749729 107750392
SANH107668577 107680670
SGH107594906 107594949
CCAR109102592
CAUA113057593 113114018
PPRM120461143(mif)
MAMB125259387(mif)
IPU100305114(mif)
PHYP113542806(mif)
SMEO124386075(mif)
TFD113647695(mif)
AMEX103031017(mif)
EEE113570789(mif)
TRU115246418 503499(mif)
LCO104922620(mif)
NCC104961162(mif)
CGOB115014986(mif)
ELY117260736(mif)
PLEP121948035(mif)
SLUC116052544(mif)
ECRA117951471(mif)
PFLV114563124(mif)
GAT120817659 120817660
PPUG119210160 119210900(mif)
MSAM119887751 119888943
CUD121515966(mif)
ALAT119006977(mif)
MZE101480066(mif)
ONL100705586(mif)
OAU116334267(mif)
OLA101160246(mif)
OML112153140(mif)
XMA102232566(mif)
XCO114138982(mif)
XHE116714232(mif)
PRET103471348(mif)
PFOR103147461(mif)
PLAI106942131(mif)
PMEI106928365(mif)
GAF122836659(mif)
CVG107101020(mif)
CTUL119796530(mif)
GMU124860684(mif)
NFU107372730(mif)
KMR108243064(mif)
ALIM106536652(mif)
NWH119408451(mif) 119428284
AOCE111578098 111583658
CSEM103390923(mif)
POV109642286(mif)
SSEN122778156(mif)
HHIP117768934(mif)
HSP118112085(mif)
LCF108885537(mif)
SDU111232407(mif)
SLAL111662789(mif)
XGL120785606(mif)
HCQ109524441(mif) 109524442
BPEC110162381(mif)
MALB109957277(mif)
BSPL114864521(mif)
SASA100136498(mif) 100196518(mif)
OTW112220788 112256110
OMY100136346(mif) 110488642
OGO123994045 124011266
ONE115130553
SALP111965412 112069058
SNH120047491 120062034
ELS105025208(mif)
SFM108930909(mif)
PKI111859339(mif)
AANG118231306(mif)
LOC102696411(mif)
PSPA121297362 121299851
ARUT117426147 117428476
LCM102367089(MIF)
RTP109919405(mif)
BFO118425486 118426506
BBEL109465853 109475171
CIN100175627 100183461
SCLV120330639
SPU105440032 105444560 577624 762494
APLC110976984 110976985 110979298 110980696
SKO100369257
BCOO119070746
TCA100142248 656105
DPA109537033
SOY115888957
ATD109602756
CSET123319835
AGB108906535
LDC111515623
APLN108735183
OTU111425279
BMOR101743564 692890(Mif)
BMAN114246772 114247038
MSEX115455689
DPLKGM_203325 KGM_206951
BANY112048412 112056751
PMAC106714533 106717204
PPOT106109840 106110283
PXU106117964 106126469
PRAP110993229
ZCE119834462 119835744
HAW110373655 110374504 110376561
TNL113494362
SLIU111359953 111361049
OFU114350893 114360428
PXY105388160
API100144890 100161225 100162394 100164929 100165124 100570612 103309364
DNX107161760 107165403 107171358 107171635 107171636 107173839
AGS114122934 114131014 114131726 114132070 114132306 114132313
RMD113549713 113551009 113552179 113553129 113554219 113560834
BTAB109031233
DCI103511645
NLU111051177
ZNE110836479
CSEC111864355
DPXDAPPUDRAFT_308977
DMK116931660
PVM113803303 113803305
PJA122255693
PCHN125029606
HAME121856207
PCLA123771470
PTRU123509989 123515620
HAZT108670939
EAF111703199
PPOI119109002 119109362 119109819 119111040
DSV119446454
RSAN119389636
RMP119180635
VDE111252489
VJA111262112
TUT107362257
DPTE113793588 113796894
DFR124491505 124497230
CSCU111629685
PTEP107451984
SDM118199802
CELCELE_Y56A3A.3(mif-1)
CBRCBG_13302(Cbr-mif-1)
BMYBM_BM6870(Bma-mif-1)
LOALOAG_08159
NAINECAME_06445 NECAME_08442
TSPTsp_06335 Tsp_06336
HROHELRODRAFT_147095 HELRODRAFT_180615
LGILOTGIDRAFT_176471 LOTGIDRAFT_231585
PCAN112559495 112561180 112568008
BGT106078321
HRF124115337 124117819 124117820 124117821 124117827 124117829 124117833 124117835 124118493 124118497 124132654
HRJ124270519 124270520 124270521 124270522 124274980 124280824 124282216 124286119
CRG105319375 105343631
MYI110458563 110458573 110458584
PMAX117320538 117329303 117333357
MMER123533841 123534231
OBI106879456 106881859
OSN115221580 115221638
LAK106150929 106153859 106153864
NVE5509214
EPA110232890
ATEN116288847
PDAM113685667
SPIS111339939
HMG101239707
TADTRIADDRAFT_53604
ATHAT5G57170
ALY9302262 9302263 9306977 9312166
CRB17876610 17886287
CSAT104709013 104711711 104726269 104734043 104761793 104768294 104780999 104791410
EUSEUTSA_v10010841mg EUTSA_v10015052mg
BRP103841091 103845155
BNA106364820 106364847 106370341 106416472 106440092 106448248
BOE106303958 106311128 106315787 106334590
RSZ108809731 108810056 108825487 108845748
THJ104806117 104817772
CPAP110811091
CIT102607528 102630667 102631169
CICCICLE_v10009962mg CICLE_v10013125mg CICLE_v10013158mg
PVY116118784 116129766
MINC123192725 123194673 123201978
TCC18589402 18597450 18597451
GRA105786590 105790896 105799984
GHI107890930 107924291 107937047 107938969 107939691 121220284
GAB108452611 108461669 108462181
DZI111295008 111295499 111304280 111312093
EGR104426349 104426350 104426351 104426393 104427838 104435924
GMX100305839 100306650
GSJ114381349 114395024 114395206 114416543 114416568 114419127
PVUPHAVU_003G141000g PHAVU_008G092400g PHAVU_008G092500g
VRA106754874 106765688
VAR108322114 108347027
VUN114177312 114183504 114184157
CCAJ109802349 109802604 109809139 109818158
APRC113847526
MTRMTR_4g014040 MTR_4g127360 MTR_7g059460
CAM101503432 101506823 101509336
LJALj0g3v0322299.1(Lj0g3v0322299.1) Lj4g3v2139180.1(Lj4g3v2139180.1)
ADU107475370 107475372 107485033 107495472 107496390
AIP107625807 107625809 107637980 107642812
AHF112697506 112723605 112728074 112728076 112740526 112743735 112751104 112751116 112794366 112797105
LANG109325198 109352671 109361572 109362073
FVE101295703 101306351
RCN112191418 112191523 112197438
PPER18774386 18789679
PMUM103323646 103342903
PAVI110758344 110767303
PDUL117631785 117632503
MDM103412348 103419406 103433707 103451003 114819951
PXB103929361 103950459 103962144 103962145
ZJU107428926 107431054 107431060
MNT21389095 21392818 21392822
CSV101203411 101208581 101215141
CMO103494235 103502167 103502168
BHJ120071481 120072663 120074491
MCHA111006808 111013854 111013868 111013871
CMAX111466128 111471895 111478343
CMOS111432434 111432436 111433078 111453099
CPEP111782212 111792312 111803070
RCU8263125 8263126 8279554
JCU105631082 105648086 105648087
HBR110633729 110633740 110636501 110650961 110667767
MESC110616665 110620055 110620357 110623510 110623511
POP18110655 7460405 7474727 7487340 7487343 7488724 7488725
PEU105119464 105119465 105121898 105121902 105122555 105131372 105141313 105141315
PALZ118033601 118039354 118039355 118039356 118039357 118048161 118048165 118056124 118056131 118056153
JRE109003088 109013656
QSU112012605 112015170 112015179
QLO115952508 115953953 115975716
TWL119981986 119989510 119995010 120013291
VVI100251764 100256897 100266836
VRI117921253 117921324 117924573
SLY101253800 101255350
SPEN107026310 107032411
SOT102582498 102602878
CANN107844958 107877786
NTA107762576 107771315 107775000 107788402 107816944
NSY104212826 104231564 104236053 104246674
NTO104086153 104093135 104101288
NAU109228691 109233313 109233400 109235695
INI109159053 109181050 109181365 109191680
ITR115998805 116006214 116007654 116030824
SIND105173900 105174616
OEU111366312 111387590 111399315 111408036
EGT105949996 105952816 105953136
SSPL121749670 121753382 121760083 121794777
HAN110877608 110886173 110915213 110916340
ECAD122592646 122593561 122595272
LSV111878214 111878217 111890767 111914392
CCAV112506795 112507106 112517292
DCR108193498 108217932 108219355
CSIN114266303 114307867 114307869
BVG104892565 104892566 104898774
SOE110786692 110794754
CQI110684583 110710765 110733874 110734720
NNU104597256 104602505 104609064
MING122089183
TSS122641315
PSOM113298891 113310569 113322445 113329228 113340649 113358665
NCOL116259999
OSA4341957 4349563 4351273
DOSAOs06t0699500-01(Os06g0699500) Os11t0107500-01(Os11g0107500) Os12t0107500-01(Os12g0107500)
OBR102704815 102717469 102720003
BDI100834365 100841922 100846149
ATS109734531 109735416
TDC119300992 119308509 119334254 119335265
TAES123103205 123111397 123148674 123159229 123164674
TUA125508713 125525890
SBI8055497 8063823 8079974
ZMA100284350 100284546
SITA101764466 101765900 101774678
SVS117833199 117852545 117863628
PVIR120668677 120679824 120704374 120713612
PHAI112886316 112888876 112897453 112898041 112903441
PDA103696432 103717501 103722612
EGU105050858 105057162
MUS103974496 103984178 103986889 103992538
DCT110110165 110113531
PEQ110023443 110033913
AOF109843024 109849899
ATR18440677
SMOSELMODRAFT_117499 SELMODRAFT_147673 SELMODRAFT_76736
PPP112290375
CRECHLRE_17g700100v5
VCNVOLCADRAFT_83092
MNGMNEG_7054
CSLCOCSUDRAFT_57937
CVRCHLNCDRAFT_136510
OLUOSTLU_17653
OTAOT_ostta12g02430
BPGBathy07g02340
MPPMICPUCDRAFT_9312
CMECYME_CMT251C
GSLGasu_17280
PBLPAAG_01158
PBNPADG_03671
AJEHCAG_05903
BGHBDBG_03359
PPLPOSPLDRAFT_105444 POSPLDRAFT_28475 POSPLDRAFT_88655
TVSTRAVEDRAFT_138052 TRAVEDRAFT_36441 TRAVEDRAFT_46171
DSQDICSQDRAFT_104168
PCOPHACADRAFT_207427 PHACADRAFT_261823
SHSSTEHIDRAFT_108811
HIRHETIRDRAFT_470362
PSQPUNSTDRAFT_122774 PUNSTDRAFT_69339 PUNSTDRAFT_88614
ADLAURDEDRAFT_116659 AURDEDRAFT_133858 AURDEDRAFT_138911 AURDEDRAFT_173029
FMEFOMMEDRAFT_104675
GTRGLOTRDRAFT_120269
LBCLACBIDRAFT_324849
MRRMoror_5129 Moror_5555 Moror_715
MOREE1B28_013158
CCICC1G_10833
SCMSCHCODRAFT_106144 SCHCODRAFT_232893 SCHCODRAFT_232894
ABPAGABI1DRAFT111593(AGABI1DRAFT_111593) AGABI1DRAFT69253(AGABI1DRAFT_69253)
ABVAGABI2DRAFT200279(AGABI2DRAFT_200279) AGABI2DRAFT217233(AGABI2DRAFT_217233)
CPUTCONPUDRAFT_144997 CONPUDRAFT_150320 CONPUDRAFT_70300 CONPUDRAFT_80073
SLASERLADRAFT_397185 SERLADRAFT_397187 SERLADRAFT_474679
SREPTSG_12443
EIVEIN_113870 EIN_174020
PYOPY17X_1446500
PCBPCHAS_144620(PC000788.00.0)
PBEPBANKA_1444000
PKNPKNH_1448700
PCYPCYB_145500
TGOTGME49_290040
NGDNGA_2067700(MIF)
AAFAURANDRAFT_30541
PIFPITG_16205 PITG_16206
PSOJPHYSODRAFT_247002 PHYSODRAFT_285242 PHYSODRAFT_285243 PHYSODRAFT_295775
EHXEMIHUDRAFT_358508 EMIHUDRAFT_360168
GTTGUITHDRAFT_76592 GUITHDRAFT_83763
LIFLINJ_33_1840(MIF1)
LDOLDBPK_331840
LMILMXM_32_1740
LBZLBRM_33_2010
LPANLPMP_331830
TVATVAG_101850 TVAG_219770
GLAGL50803_0012091
MCAMCA2795
METUGNH96_00580
MMTMetme_0569
MDNJT25_012665
MDHAYM39_02460
MKOMKLM6_0534
METLU737_22220
MPADKEF85_16330
MELLIVG45_20730
MAHMEALZ_0491(MIF)
MBUREQU24_19420
MMAIsS8_5297
MMOBF6R98_09645
MEINmethR_P1855
MOZMoryE10_18470
MEJQ7A_2253
MECQ7C_2463
MPINLGT42_007145
THISHZT40_07145
TMBThimo_1880
MPURMARPU_14525
TEETel_09965
TSYTHSYN_03235
TTPE6P07_03845
THIPN838_20630
CJAPGWK36_13625
TGRTgr7_1126
TKMTK90_0504
TNITVNIR_3391
TTITHITH_02825
TVRTVD_10075
APRSBI364_12080
SLIMSCL_2004
TBNTBH_C0828
REVHUE57_15620
EPSL0Y14_03405
ENMEBS_0375
DFLDFE_0354
DMSE8L03_19315
DEJAWY79_09500
PPRFDPRO_1243
PSELGM415_10775
DDNDND132_0930
DBADbac_2063
DALDalk_3117
DOVDSCO28_55940
DWDDSCW_22500
DALKDSCA_43460
DEXHWD60_06260
MAGQMGMAQ_1296
MAESGa0123461_0564
MFNGa0123462_1699
TPDTeth39_1610
TITThit_0686
TMTTmath_0739
TBOThebr_1650
TWIThewi_0839
TKITKV_c07050
TTMTthe_1010
TTOThethe_00962
TXYThexy_1717
TSHTsac_1471
HASHalsa_0970
SYDSyncc9605_1073
SYESyncc9902_1470
SYXSynWH7803_0947
SYPSYNPCC7002_A0567
CYACYA_2597
CYBCYB_0558
SYNDKR52_11595
SYHSyncc8109_1600
SYVAWQ23_02995
SYLAWQ21_02975
SYNCCB0101_02095
SYWSYNW0376
CYICBM981_0145
PMMPMM1167
PMTPMT_0503
PMNPMN2A_0714
PMIPMT9312_1267
PMBA9601_13581
PMFP9303_17651
PMGP9301_13671
PMHP9215_13791
PMENATL1_15511
PRCEW14_1414
PRMEW15_1613
CMPCha6605_1431
AMRAM1_1005
LEPLepto7376_1667
LENLEP3755_14590
LETO77CONTIG1_02474
HHGXM38_023300
PSEUPse7367_1549
THEUHPC62_01355
GLPGlo7428_1654
GEEGM3708_3155
MARMAE_29020
MPKVL20_5280
MIQB5D77_21225
MVZmyaer102_05040
CSNCyast_1911
CYLAA637_09210
HAOPCC7418_2439
CYTcce_2084
CWACwatDRAFT_5612
CYPPCC8801_2603
CYHCyan8802_3503
CYCPCC7424_3169
CYJCyan7822_2502
CYNCyan7425_4718
TERTery_1915
ARPNIES39_H00420 NIES39_H00430
OXYHCG48_05330
LFSHFV01_17870 HFV01_17875
MICMic7113_1717
GEIGEI7407_0030
OACOscil6304_5465
MPROBJP34_26070
NOSNos7107_4337
NOPNos7524_1812
NEDHUN01_14445
ACYAnacy_1558
CSGCylst_4922
CALOCal7507_0789
CALTCal6303_5502
CALHIJ00_02520
RIVRiv7116_1527
TOQHCG51_07840
NCNBZZ01_27075
CTHEChro_4899
PLPPle7327_2175
SCSSta7437_1222
STANSTA3757_23340
CERRGRSB_1926
OBGVerru16b_01893
VBHCMV30_02210
CAACaka_1114
MINMinf_2366
MKCkam1_115
VBSEGM51_11025
SSMSpirs_1314
BLQL21SP5_01065
MBASALGA_3422
PMOPmob_1555
ASACATHSA_1397
 » show all
Reference
1  [PMID:5824560]
  Authors
Blasi F, Fragomele F, Covelli I.
  Title
Thyroidal phenylpyruvate tautomerase. Isolation and characterization.
  Journal
J Biol Chem 244:4864-70 (1969)
Reference
2
  Authors
Knox, W.E.
  Title
p-Hydroxyphenylpyruvate enol-keto tautomerase.
  Journal
Methods Enzymol 2:289-295 (1955)
Reference
3  [PMID:13416270]
  Authors
KNOX WE, PITT BM.
  Title
Enzymic catalysis of the keto-enol tautomerization of phenylpyruvic acids.
  Journal
J Biol Chem 225:675-88 (1957)
Other DBs
ExplorEnz - The Enzyme Database: 5.3.2.1
IUBMB Enzyme Nomenclature: 5.3.2.1
ExPASy - ENZYME nomenclature database: 5.3.2.1
BRENDA, the Enzyme Database: 5.3.2.1
CAS: 9023-54-5

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