| Entry |
|
|---|
| Name |
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming);
TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase (ambiguous);
Tyl1a;
dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase (ambiguous)
|
|---|
| Class |
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
|
|---|
| Sysname |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose isomerase
|
|---|
| Reaction(IUBMB) |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose [RN: R06424]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose [CPD: C11907]
|
|---|
| Product |
dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose [CPD: C11908]
|
|---|
| Comment |
The enzyme is involved in biosynthesis of D-mycaminose.
|
|---|
| History |
EC 5.3.2.4 created 2011
|
|---|
| Pathway |
| ec00523 | Polyketide sugar unit biosynthesis |
| ec00541 | O-Antigen nucleotide sugar biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
|
|---|
| Orthology |
| K19853 | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase |
| K24249 | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase |
|
|---|
| Genes |
|
|---|
| Reference |
|
|---|
| Authors |
Melancon CE 3rd, Hong L, White JA, Liu YN, Liu HW |
|---|
| Title |
Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 5.3.2.4 |
| ExPASy - ENZYME nomenclature database: | 5.3.2.4 |
| BRENDA, the Enzyme Database: | 5.3.2.4 |
|
|---|
