KEGG   ENZYME: 5.3.2.5Help
Entry
EC 5.3.2.5                  Enzyme                                 

Name
2,3-diketo-5-methylthiopentyl-1-phosphate enolase;
DK-MTP-1-P enolase;
MtnW;
YkrW;
RuBisCO-like protein;
RLP;
2,3-diketo-5-methylthiopentyl-1-phosphate keto---enol-isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
BRITE hierarchy
Sysname
5-(methylsulfanyl)-2,3-dioxopentyl phosphate keto---enol-isomerase
Reaction(IUBMB)
5-(methylsulfanyl)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate [RN:R07393]
Reaction(KEGG)
Substrate
5-(methylsulfanyl)-2,3-dioxopentyl phosphate [CPD:C15650]
Product
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate [CPD:C15651]
Comment
The enzyme participates in the methionine salvage pathway in Bacillus subtilis [2].In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 3.1.3.87, 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [1].
History
EC 5.3.2.5 created 2012
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
Orthology
K08965  2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Genes
ACII: C4901_00435
AFE: Lferr_0596
AFR: AFE_0434(ccbL2)
ACU: Atc_2430
ACZ: Acaty_c2269
AFI: Acife_0637
BSU: BSU13590(mtnW)
BSR: I33_1530(mtnW)
BSL: A7A1_1503
BSH: BSU6051_13590(mtnW)
BSY: I653_06975(mtnW)
BSUT: BSUB_01479(mtnW)
BSUL: BSUA_01479(mtnW)
BSUS: Q433_07770(mtnW)
BSS: BSUW23_06980(mtnW)
BST: GYO_1686(mtnW)
BSO: BSNT_07850(mtnW)
BSN: BSn5_18840(mtnW)
BSQ: B657_13590(mtnW)
BSX: C663_1400(mtnW)
BLI: BL03540(mtnW)
BLD: BLi01515(mtnW)
BLH: BaLi_c15940(mtnW)
BAY: RBAM_013370(mtnW)
BAQ: BACAU_1314(mtnW)
BYA: BANAU_1273(mtnW)
BAMP: B938_06955(mtnW)
BAML: BAM5036_1273(mtnW)
BAMA: RBAU_1315(mtnW)
BAMN: BASU_1294(mtnW)
BAMB: BAPNAU_2426(mtnW)
BAMT: AJ82_07680(mtnW)
BAMY: V529_12890(mtnW)
BMP: NG74_01393(mtnW)
BAO: BAMF_1441(mtnW)
BAZ: BAMTA208_10340(mtnW)
BQL: LL3_01461(mtnW)
BXH: BAXH7_02114(mtnW)
BQY: MUS_1440(mtnW)
BAMI: KSO_012680(mtnW)
BAMC: U471_13600
BAMF: U722_07145(mtnW)
BAE: BATR1942_04550(mtnW)
BATR: TD68_04045(mtnW)  
BAN: BA_4255(mtnW)
BAR: GBAA_4255(mtnW)
BAT: BAS3946(mtnW)
BAH: BAMEG_4296(mtnW)
BAI: BAA_4278(mtnW)
BANT: A16_42560
BANR: A16R_43100
BANS: BAPAT_4080
BANH: HYU01_20790(mtnW)
BANV: DJ46_2947(mtnW)
BCE: BC4036(mtnW)
BCA: BCE_4103
BCZ: BCE33L3793(rbcL)
BCR: BCAH187_A4167(mtnW)
BCB: BCB4264_A4145(mtnW)
BCU: BCAH820_4057(mtnW)
BCG: BCG9842_B1093(mtnW)
BCQ: BCQ_3826(rbcL)
BCX: BCA_4149(mtnW)
BNC: BCN_3948
BCF: bcf_20075
BCER: BCK_15020(mtnW)
BTK: BT9727_3778(mtnW)
BTL: BALH_3653
BTB: BMB171_C3700(mtnW)
BTT: HD73_4335
BTHR: YBT1520_21490(mtnW)
BTHI: BTK_21340(mtnW)
BTC: CT43_CH4042(mtnW)
BTF: YBT020_19870(mtnW)
BTM: MC28_3328(mtnW)
BTG: BTB_c41710(mtnW)
BTI: BTG_29240(mtnW)
BTN: BTF1_18495(mtnW)
BTHU: YBT1518_22360(mtnW)
BTW: BF38_5209(mtnW)
BTHY: AQ980_09670(mtnW)
BWW: bwei_0915(mtnW)
BMYO: BG05_1986(mtnW)
BMYC: DJ92_1131(mtnW)
BBY: CY96_19270(mtnW)
BCL: ABC1775(mtnW)
BPU: BPUM_1252(mtnW)
BPUM: BW16_07065(mtnW)
BPUS: UP12_06570(mtnW)
BPF: BpOF4_14675(mtnW)
BMQ: BMQ_1250(mtnW)
BMD: BMD_1234(mtnW)
BMH: BMWSH_3986(mtnW)
BMEG: BG04_3549(mtnW)
BJS: MY9_1488
BIF: N288_08395(mtnW)
BMET: BMMGA3_05045(mtnW)
GST: HW35_15685(mtnW)
BACW: QR42_06425(mtnW)
BACP: SB24_03030(mtnW)
BACB: OY17_09780(mtnW)
BACY: QF06_05805(mtnW)
BACL: BS34A_15100(mtnW)
BALM: BsLM_1440
BEO: BEH_04815
BSJ: UP17_14160(mtnW)
BON: A361_08445(mtnW)
BGY: BGLY_1452(mtnW)
BKW: BkAM31D_06395(mtnW)
BALT: CFN77_06935(mtnW)
BACS: AUL54_03855(mtnW)
BIT: BIS30_17595(mtnW)
GKA: GK0953
GTK: GT3570_04590(mtnW)
GTN: GTNG_0841
GGH: GHH_c08900(mtnW)
GJF: M493_04885(mtnW)
GEA: GARCT_00965(mtnW)
GSE: GT50_14450(mtnW)
GSR: GS3922_11660(mtnW)
GEJ: A0V43_02065(mtnW)
PTL: AOT13_07930(mtnW)
AFL: Aflv_1997
AGN: AFK25_04400(mtnW)
ANM: GFC28_1480(mtnW)
AAMY: GFC30_1262(mtnW)
ANL: GFC29_148(mtnW)
FPN: ABE65_007245(mtnW)
MCAK: MCCS_23710(mtnW)
ESI: Exig_0430
EAN: Eab7_0405(mtnW)
EXM: U719_02210(mtnW)
BBE: BBR47_48900(mtnW)
PPY: PPE_02689(mtnW)
PPM: PPSC2_14325(ykrW)
PPO: PPM_2881(ykrW)
PPOL: X809_30750(mtnW)
PPQ: PPSQR21_028520(rbcL)
PPOY: RE92_22375(mtnW)
PMS: KNP414_04026(mtnW)
PTA: HPL003_23125(mtnW)
PLV: ERIC2_c14190(mtnW)
PBJ: VN24_24480(mtnW)
PIH: UB51_05770(mtnW)
PPEO: ABE82_14765(mtnW)
PSWU: SY83_18315(mtnW)
PAIH: ASL14_23615(mtnW)
PVO: PVOR_13854(mtnW)
ANX: ACH33_15410(mtnW)
ASOC: CB4_03885(mtnW)
AAC: Aaci_0096
AAD: TC41_0117(mtnW)
JEO: JMA_33120
SURE: SporoP32a_07290(mtnW)
CSQ: CSCA_0840
SAY: TPY_2539(mtnW)
NML: Namu_0013
MAR: MAE_13070
MPK: VL20_1894
LFC: LFE_0827
MOX: DAMO_2930(mtnW)
AFU: AF_1587
LOKI: Lokiarch_12480(mtnW_1) Lokiarch_14140(mtnW_2)
 » show all
Taxonomy
Reference
1  [PMID:8227039]
  Authors
Myers RW, Wray JW, Fish S, Abeles RH.
  Title
Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
  Journal
J Biol Chem 268:24785-91 (1993)
Reference
2  [PMID:14551435]
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
  Sequence
[bsu:BSU13590]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.2.5
IUBMB Enzyme Nomenclature: 5.3.2.5
ExPASy - ENZYME nomenclature database: 5.3.2.5
BRENDA, the Enzyme Database: 5.3.2.5

DBGET integrated database retrieval system