KEGG   ENZYME: 5.3.2.5
Entry
EC 5.3.2.5                  Enzyme                                 
Name
2,3-diketo-5-methylthiopentyl-1-phosphate enolase;
DK-MTP-1-P enolase;
MtnW;
YkrW;
RuBisCO-like protein;
RLP;
2,3-diketo-5-methylthiopentyl-1-phosphate keto---enol-isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
Sysname
5-(methylsulfanyl)-2,3-dioxopentyl phosphate keto---enol-isomerase
Reaction(IUBMB)
5-(methylsulfanyl)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate [RN:R07393]
Reaction(KEGG)
R07393
Substrate
5-(methylsulfanyl)-2,3-dioxopentyl phosphate [CPD:C15650]
Product
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate [CPD:C15651]
Comment
The enzyme participates in the methionine salvage pathway in Bacillus subtilis [2].In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 3.1.3.87, 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [1].
History
EC 5.3.2.5 created 2012
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
Orthology
K08965  2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Genes
ACIIC4901_00435
ATYA9R16_000375
AFRAFE_0434(ccbL2)
AFELferr_0596
ACUAtc_2430
ACZAcaty_c2269
AFIAcife_0637
AFJAFERRID_16700
ATXGCD22_00526(mtnW)
AFPK1Y48_02540
BSUBSU13590(mtnW)
BSRI33_1530(mtnW)
BSLA7A1_1503
BSHBSU6051_13590(mtnW)
BSYI653_06975(mtnW)
BSUTBSUB_01479(mtnW)
BSULBSUA_01479(mtnW)
BSUSQ433_07770(mtnW)
BSOBSNT_07850(mtnW)
BSNBSn5_18840(mtnW)
BSQB657_13590(mtnW)
BSXC663_1400(mtnW)
BSPU712_07110
BSSBSUW23_06980(mtnW)
BSTGYO_1686(mtnW)
BLIBL03540(mtnW)
BLDBLi01515(mtnW)
BLHBaLi_c15940(mtnW)
BAYRBAM_013370(mtnW)
BAQBACAU_1314(mtnW)
BYABANAU_1273(mtnW)
BAMPB938_06955(mtnW)
BQYMUS_1440(mtnW)
BAMLBAM5036_1273(mtnW)
BAMARBAU_1315(mtnW)
BAMNBASU_1294(mtnW)
BAMBBAPNAU_2426(mtnW)
BAMTAJ82_07680(mtnW)
BAMYV529_12890(mtnW)
BMPNG74_01393(mtnW)
BAOBAMF_1441(mtnW)
BAZBAMTA208_10340(mtnW)
BQLLL3_01461(mtnW)
BXHBAXH7_02114(mtnW)
BAMIKSO_012680(mtnW)
BAMCU471_13600
BAMFU722_07145(mtnW)
BSIACWD84_14565(mtnW)
BAEBATR1942_04550(mtnW)
BVMB9C48_06840
BSONS101395_03400(mtnW)
BHTDIC78_02645(mtnW)
BMOJHC660_14280(mtnW)
BTEQG4P54_07130(mtnW)
BIQAN935_07085(mtnW)
BANBA_4255(mtnW)
BARGBAA_4255(mtnW)
BATBAS3946
BAHBAMEG_4296(mtnW)
BAIBAA_4278(mtnW)
BAXH9401_4055
BANTA16_42560
BANRA16R_43100
BANSBAPAT_4080
BANHHYU01_20790(mtnW)
BANVDJ46_2947(mtnW)
BCEBC4036
BCABCE_4103
BCZBCE33L3793(rbcL)
BCRBCAH187_A4167(mtnW)
BCBBCB4264_A4145(mtnW)
BCUBCAH820_4057(mtnW)
BCGBCG9842_B1093(mtnW)
BCQBCQ_3826(rbcL)
BCXBCA_4149(mtnW)
BALBACI_c40050
BNCBCN_3948
BCFbcf_20075
BCERBCK_15020(mtnW)
BCEFBcrFT9_03150
BCYBcer98_2735
BTKBT9727_3778(rbcL)
BTLBALH_3653
BTBBMB171_C3700(mtnW)
BTTHD73_4335
BTHRYBT1520_21490(mtnW)
BTHIBTK_21340(mtnW)
BTCCT43_CH4042(mtnW)
BTFYBT020_19870(mtnW)
BTMMC28_3328(mtnW)
BTGBTB_c41710(mtnW)
BTIBTG_29240(mtnW)
BTNBTF1_18495(mtnW)
BTHTH175_ch4108
BTHUYBT1518_22360(mtnW)
BTWBF38_5209(mtnW)
BTHYAQ980_09670(mtnW)
BWEBcerKBAB4_3865
BWWbwei_0915(mtnW)
BMYOBG05_1986(mtnW)
BTYBtoyo_1281
BMYCDJ92_1131(mtnW)
BBYCY96_19270(mtnW)
BWDCT694_21720(mtnW)
BTROFJR70_13925(mtnW)
BMOBMLA2C4_21110(mtnW)
BNTGSN03_19125(mtnW)
BPACLMD38_06905(mtnW)
BPANNLJ82_19615(mtnW)
BPUBPUM_1252(mtnW)
BPUMBW16_07065(mtnW)
BPUSUP12_06570(mtnW)
BIFN288_08395(mtnW)
BMETBMMGA3_05045(mtnW)
BSMBSM4216_3456
BGYBGLY_1452(mtnW)
BWHA9C19_12800
BXIBK049_01795
BALTCFN77_06935(mtnW)
BAERBAE_14150(mtnW)
BSAFBSL056_06540
BITBIS30_17595(mtnW)
BBADK7T73_02620
BCABEFK13_07590(mtnW)
BRYM0696_07435(mtnW)
BJSMY9_1488
GSTHW35_15685(mtnW)
BACWQR42_06425(mtnW)
BACPSB24_03030(mtnW)
BACBOY17_09780(mtnW)
BACYQF06_05805(mtnW)
BACLBS34A_15100(mtnW)
BALMBsLM_1440
BACSAUL54_03855(mtnW)
BACQDOE78_07025
BHKB4U37_07785
BCOHBC6307_09130
BMQBMQ_1250(mtnW)
BMDBMD_1234(mtnW)
BMHBMWSH_3986(mtnW)
BMEGBG04_3549(mtnW)
BEOBEH_04815
BFXBC359_14805
PKSIE339_04950(mtnW)
BCLABC1775(mtnW)
BLEBleG1_0631 BleG1_1589
BKWBkAM31D_06395(mtnW)
BGIBGM20_01135
BPFBpOF4_14675(mtnW)
BONA361_08445(mtnW)
BKOCKF48_04400
CGOTJ1899_12690
CSUAIM538_06115(mtnW)
CFIRNAF01_07950
GKAGK0953
GTEGTCCBUS3UF5_11270
GTKGT3570_04590(mtnW)
GTMGT3921_14695
GLIGLN3_15045
BCALCWI35_05370(mtnW)
GTNGTNG_0841
GWCGWCH70_0850
GYCGYMC61_1745
GYAGYMC52_0871
GCTGC56T3_2602
GMCGY4MC1_2913
GGHGHH_c08900(mtnW)
GJFM493_04885(mtnW)
GEAGARCT_00965(mtnW)
GSEGT50_14450(mtnW)
GSRGS3922_11660(mtnW)
GEJA0V43_02065(mtnW)
GZAIC807_00530(mtnW)
PTLAOT13_07930(mtnW)
PTBDER53_08875(mtnW)
PCALBV455_00903(mtnW)
PARGPspKH34_28400(mtnW)
AFLAflv_1997
AGNAFK25_04400(mtnW)
ANMGFC28_1480(mtnW)
AAMYGFC30_1262(mtnW)
ANLGFC29_148(mtnW)
ANDGRQ40_05510(mtnW)
ACAIISX45_02035(mtnW)
ASEDIRT44_02480
FPNABE65_007245(mtnW)
FARABE41_008290
APAKAP3564_01620
BSJUP17_14160(mtnW)
BMURABE28_013145
PBUTDTO10_01370(mtnW)
PFRIL8956_14710(mtnW)
PSYOPB01_20415(mtnW)
NTMBTDUT50_06095(mtnW)
MEKUHUW50_18085(mtnW)
MSEMGMB29_14935(mtnW)
MDGK8L98_09000(mtnW)
MLITKDJ21_023015(mtnW)
BVQFHE72_08645
RMFD5E69_09030
MCUIG8O30_03760
GAJMY490_13400
PSUAFLK61_24150
MJOFOF60_07540(mtnW)
MCAKMCCS_23710(mtnW)
MACRBHM04_11610
MBOEHT586_11470
MBRUMGG13_10480
MEPIKFV12_12355
MEQUKFV11_01855
ESIExig_0430
EATEAT1b_1436
EANEab7_0405(mtnW)
EXMU719_02210(mtnW)
EXUESP131_04655
EAPKB235_03365
EACEKKI46_02470
EAURNMQ00_01800
BBEBBR47_48900(mtnW)
BLRBRLA_c041920
BFMBP422_20265
BAGRBA6348_07050
BRWGOP56_13485
BCHSJNE38_26585
BCOPJD108_04270
PJDPjdr2_2465
GYMGYMC10_2267
PPYPPE_02689(mtnW)
PPMPPSC2_14325(ykrW)
PPOPPM_2881(ykrW)
PPOLX809_30750(mtnW)
PPQPPSQR21_028520(rbcL)
PPOYRE92_22375(mtnW)
PMSKNP414_04026(mtnW)
PMQPM3016_5397
PTAHPL003_23125(mtnW)
PLVERIC2_c14190(mtnW)
PBJVN24_24480(mtnW)
PIHUB51_05770(mtnW)
PPEOABE82_14765(mtnW)
PNPIJ22_10280
POWIJ21_24230
PBVAR543_16260
PXLBS614_22280
PSWUSY83_18315(mtnW)
PIBBBD41_03790
PKBB4V02_10810
PAIHASL14_23615(mtnW)
PVOPVOR_13854(mtnW)
PLWD5F53_18330
PLENEIM92_14625
PPSCEHS13_19035
PALBEJC50_22025
PCHIPC41400_12055
PBKBack11_10090(mtnW)
PPRTET464_06640
PBACHUB98_04715
PRZGZH47_28900
PLYCGXP70_18720
PALOE6C60_1902
PCELHUB94_14295
PALRHGI30_10460
TCOTheco_1802
ANXACH33_15410(mtnW)
ASOCCB4_03885(mtnW)
ATHEK3F53_03445
COHEAV92_08895
CCHLFPL14_27115
CHEBHH215_04230
AACAaci_0096
AADTC41_0117(mtnW)
AFXJZ786_04785
AACOK1I37_01135
ACURJZ785_14605
ADAUNZD86_01665
AFASNZD89_01225
TUMCBW65_12825
TABCIG75_15780
EFFskT53_15370(mtnW)
PANABBH88_03600
PDGBCM40_00535
PHCBBI08_11895
PMARB0X71_16600
PPLABBI15_12965
PLXCW734_02320
PGQFK545_06705(mtnW)
JEOJMA_33120
SURESporoP32a_07290(mtnW)
SPOSDV702_00170
PANCE2636_08755
PLAYDNR44_004080(mtnW)
LFBC1X05_12315
TVUAB849_002715
PABSJIR001_28090(mtnW)
SAYTPY_2539(mtnW)
SAPSulac_3291
ACITHPK19_08185
MARMAE_13070
MPKVL20_1894
MIQB5D77_03275
MVZmyaer102_47140
CYPPCC8801_2072
CYHCyan8802_2096
CYCPCC7424_0958
CYJCyan7822_0549
ARPNIES39_E02120
PAGHNIES204_31820
PPSUNO713_00127(mtnW)
LFSHFV01_23775
MICMic7113_2203
GEIGEI7407_0620
MPROBJP34_01135
CALTCal6303_1394
RIVRiv7116_5245
PLPPle7327_0641
SCSSta7437_1268
STANSTA3757_37710
PMXPERMA_0408
LFCLFE_0827
LFILFML04_2084
LFPY981_10670
LEGABH19_11250
MOXDAMO_2930(mtnW)
 » show all
Reference
1  [PMID:8227039]
  Authors
Myers RW, Wray JW, Fish S, Abeles RH.
  Title
Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
  Journal
J Biol Chem 268:24785-91 (1993)
Reference
2  [PMID:14551435]
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
  Sequence
[bsu:BSU13590]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.2.5
IUBMB Enzyme Nomenclature: 5.3.2.5
ExPASy - ENZYME nomenclature database: 5.3.2.5
BRENDA, the Enzyme Database: 5.3.2.5

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