KEGG   ENZYME: 5.3.99.3
Entry
EC 5.3.99.3                 Enzyme                                 
Name
prostaglandin-E synthase;
prostaglandin-H2 E-isomerase;
endoperoxide isomerase;
endoperoxide isomerase;
prostaglandin R-prostaglandin E isomerase;
prostaglandin endoperoxide E isomerase;
PGE isomerase;
PGH-PGE isomerase;
PGE2 isomerase;
prostaglandin endoperoxide E2 isomerase;
prostaglandin H-E isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Other intramolecular oxidoreductases
Sysname
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase
Reaction(IUBMB)
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate [RN:R02265]
Reaction(KEGG)
R02265
Substrate
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate [CPD:C00427]
Product
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate [CPD:C00584]
Comment
Brings about the opening of the epidioxy bridge. Requires glutathione.
History
EC 5.3.99.3 created 1976, modified 1990
Pathway
ec00590  Arachidonic acid metabolism
ec01100  Metabolic pathways
Orthology
K05309  microsomal prostaglandin-E synthase 2
K15729  microsomal prostaglandin-E synthase 1
K15730  cytosolic prostaglandin-E synthase
Genes
HSA10728(PTGES3) 80142(PTGES2) 9536(PTGES)
PTR104001457 112204098 464763(PTGES2) 473071(PTGES) 746021(PTGES3)
PPS100967263 100967487(PTGES3) 100988615(PTGES) 100990863(PTGES2)
GGO101144874(PTGES) 101146371 101151389(PTGES3) 101154357(PTGES2)
PON100174118(PTGES3) 100432421(PTGES) 100443538(PTGES2)
NLE100588011 100590065(PTGES2) 100603876(PTGES) 100607267(PTGES3)
MCC697949(PTGES2) 713353(PTGES3) 716657(PTGES)
MCF102125534(PTGES) 102140040(PTGES2) 102140495(PTGES3)
CSAB103238539(PTGES3) 103239760(PTGES) 103239810(PTGES2)
CATY105576191(PTGES) 105576238(PTGES2) 105594069
PANU101000582(PTGES2) 101015546(PTGES) 101016342(PTGES3)
TGE112608174(PTGES2) 112608678(PTGES) 112634184(PTGES3)
RRO104660539(PTGES) 104665862(PTGES2) 104673662(PTGES3)
RBB108512807(PTGES2) 108512852(PTGES) 108516043(PTGES3)
TFN117071054 117072202(PTGES2) 117072570 117073127(PTGES) 117089917(PTGES3)
PTEH111541835(PTGES3) 111545851(PTGES) 111545885(PTGES2)
CJC100384917(PTGES) 100386433(PTGES3) 100403135(PTGES2)
SBQ101029318(PTGES) 101035651(PTGES2) 101044839(PTGES3) 101045432
CSYR103250508(PTGES) 103275146(PTGES3)
MMUR105865527(PTGES3) 105875241(PTGES2) 105875286(PTGES)
LCAT123639635(PTGES3) 123646359(PTGES) 123646416(PTGES2)
OGA100946513(PTGES3) 100947895 100958673(PTGES2) 100965106(PTGES)
MMU56351(Ptges3) 64292(Ptges) 96979(Ptges2)
MCAL110287672(Ptges2) 110289384(Ptges) 110303236(Ptges3)
MPAH110318582(Ptges2) 110319350(Ptges) 110326471(Ptges3)
RNO311865(Ptges2) 362809(Ptges3) 367808(Ptges3l1) 59103(Ptges)
MCOC116076123(Ptges3) 116089957(Ptges) 116089998(Ptges2)
MUN110548989(Ptges3) 110557110(Ptges) 110561806(Ptges2)
CGE100758776(Ptges2) 100770965(Ptges) 100774202(Ptges3)
MAUA101829189(Ptges3) 101829862(Ptges2) 101830828(Ptges) 121134667
PLEU114686919(Ptges3) 114703768(Ptges) 114703801(Ptges2)
MORG121462879(Ptges) 121462980(Ptges3) 121463074(Ptges2)
AAMP119803529(Ptges3) 119805013 119819056(Ptges2) 119820024(Ptges)
NGI103727487(Ptges2) 103727860(Ptges) 103730212(Ptges3)
HGL101701326(Ptges3) 101703245(Ptges) 101712155(Ptges2)
CPOC100718334(Ptges3) 100725206(Ptges2) 100733230(Ptges)
CCAN109683234(Ptges) 109686113(Ptges3) 109686775(Ptges2) 109693023
DORD105989351(Ptges) 105989388(Ptges2) 105990016(Ptges3)
DSP122109005(Ptges) 122109056(Ptges2) 122124165(Ptges3)
NCAR124964947 124964996 124983109
OCU100342171(PTGES) 100345490(PTGES3) 100351480 100353228(PTGES2) 100355572
OPI101523695(PTGES3) 101525058(PTGES)
TUP102472868(PTGES) 102481278(PTGES2) 102494210(PTGES3)
CFA480698(PTGES) 609101(PTGES2) 612760(PTGES3)
CLUD112677259(PTGES2) 112677319(PTGES) 112678002(PTGES3)
VVP112917707 112927925(PTGES2) 112927974(PTGES)
VLG121472643(PTGES) 121473951(PTGES2)
AML100464308(PTGES3) 100465480 100469153(PTGES2) 117798720
UMR103656317(PTGES3) 103670266(PTGES) 103670289(PTGES2)
UAH113256409(PTGES3) 113266452(PTGES2) 113266512(PTGES)
UAR123775719(PTGES2) 123775739(PTGES)
ELK111146018 111146395 111160212
LLV125083026 125083802
MPUF101670143(PTGES2) 101670420(PTGES3) 101693764(PTGES)
ORO101366532(PTGES2) 101371583(PTGES3) 101375511(PTGES)
EJU114198869(PTGES) 114212932(PTGES2) 114214981(PTGES3)
ZCA113921896(PTGES3) 113934880(PTGES2) 113935055(PTGES)
MLX118008697(PTGES3) 118017594(PTGES) 118017637(PTGES2)
FCA101086187(PTGES) 101087496(PTGES3) 101098264(PTGES2)
PYU121035039(PTGES2) 121035101(PTGES) 121040908(PTGES3)
PBG122473783(PTGES3) 122474810(PTGES2) 122475395(PTGES)
PTG102950084(PTGES3) 102968135(PTGES2) 102971096(PTGES)
PPAD109250032 109250033 109250034 109250096(PTGES2) 109270346(PTGES3)
AJU106966288(PTGES2) 106986854(PTGES3) 106989376(PTGES)
HHV120219929(PTGES3) 120230158(PTGES) 120230199(PTGES2)
BTA282019(PTGES) 493638(PTGES3) 493639(PTGES2)
BOM102267091(PTGES) 102272807 102274141(PTGES2) 102281563(PTGES3)
BIU109554906 109559349(PTGES3) 109566498(PTGES2) 109566538(PTGES)
BBUB102393102(PTGES2) 102397773 102404737(PTGES3) 102410526(PTGES) 112577749
CHX102172909(PTGES2) 102181874(PTGES) 102191500(PTGES3)
OAS101101884(PTGES3) 101104140(PTGES) 101109261(PTGES2) 114118052
ODA120852023(PTGES2) 120852082(PTGES) 120857461(PTGES3)
CCAD122427287(PTGES3) 122442207(PTGES2) 122442262(PTGES)
SSC100155133(PTGES2) 100155956(PTGES3) 654407(PTGES)
CFR102508917(PTGES2) 102515833(PTGES3) 102517530(PTGES)
CBAI105065973(PTGES2) 105075873(PTGES3) 105081127(PTGES)
CDK105086350(PTGES3) 105092543(PTGES) 105092587(PTGES2)
VPC102527453(PTGES3) 102533578(PTGES) 102543557(PTGES2)
BACU103002363(PTGES2) 103003465(PTGES) 103007567(PTGES3)
LVE103077143(PTGES3) 103079015(PTGES) 103088274(PTGES2)
OOR101276928(PTGES2) 101279225(PTGES3) 101285341(PTGES)
DLE111173861(PTGES3) 111177130(PTGES) 111177181(PTGES2)
PCAD102987308(PTGES3) 102987546(PTGES2) 102991544(PTGES)
PSIU116755872(PTGES) 116755989(PTGES2) 116760421(PTGES3)
ECB100034143(PTGES) 100059858(PTGES3) 100070332(PTGES2)
EPZ103550876(PTGES2) 103551891(PTGES) 103565327(PTGES3)
EAI106832970(PTGES3) 106845312(PTGES2) 106845405(PTGES)
MYB102241912(PTGES) 102247087(PTGES3) 102262962(PTGES2)
MYD102755286(PTGES) 102758392(PTGES2) 102769484(PTGES3)
MMYO118650202(PTGES3) 118666971(PTGES) 118667016(PTGES2)
MLF102419872(PTGES2) 102425562(PTGES3) 102435907(PTGES)
MNA107524653(PTGES) 107536134(PTGES2) 107546196(PTGES3)
PKL118706669(PTGES2) 118706681(PTGES) 118729834(PTGES3) 118731381
HAI109379965(PTGES2) 109382191(PTGES) 109396906(PTGES3)
DRO112306312(PTGES2) 112306407(PTGES) 112319040(PTGES3)
SHON118975855(PTGES3) 118980210(PTGES) 118980269(PTGES2)
AJM119049480(PTGES) 119055760(PTGES2) 119062536(PTGES3)
PDIC114497852(PTGES2) 114507581(PTGES) 114512784(PTGES3)
PHAS123812894(PTGES3) 123823293(PTGES) 123823446(PTGES2)
MMF118624404(PTGES3) 118628708 118629677(PTGES2) 118630001(PTGES)
RFQ117028931(PTGES3) 117031853(PTGES2) 117032336(PTGES)
PALE102882880(PTGES3) 102883675(PTGES2) 102893846(PTGES) 102894112
PGIG120601631(PTGES) 120601723(PTGES2) 120604927(PTGES3)
PVP105294824(PTGES2) 105294883(PTGES) 105302565(PTGES3)
RAY107504536(PTGES) 107520236(PTGES2) 107521226(PTGES3)
MJV108392007(PTGES3) 108394785(PTGES) 108397983(PTGES2)
TOD119232132(PTGES) 119232223(PTGES2) 119248069(PTGES3) 119253423
SARA101538928 101543051(PTGES) 101548020 101549121(PTGES2) 101551444(PTGES3)
LAV100653828(PTGES2) 100657504(PTGES3) 100672793(PTGES)
TMU101341733 101346664 101361003
DNM101421934(PTGES) 101422367(PTGES2) 101434230 101438483(PTGES3)
MDO100012458(PTGES2) 100014431(PTGES3) 100015030(PTGES)
GAS123235228(PTGES) 123250336(PTGES3) 123254420
SHR100922238(PTGES3) 100922522(PTGES2) 100928080(PTGES)
PCW110193776(PTGES2) 110198944(PTGES) 110211129(PTGES3)
OAA100076868(PTGES) 100082173(PTGES3) 100089752(PTGES2)
GGA100859133(PTGES3) 417193(PTGES) 417214(PTGES2)
PCOC116234211(PTGES2) 116234241(PTGES) 116239816(PTGES3)
MGP100538709(PTGES3) 100545081(PTGES2) 100547804(PTGES)
CJO107321833(PTGES) 107325850(PTGES3)
NMEL110389212(PTGES3) 110407036(PTGES) 110407090(PTGES2)
APLA101793628(PTGES3) 101802868(PTGES2) 101804367(PTGES)
ACYG106047303(PTGES) 106047315(PTGES2) 106049003(PTGES3)
AFUL116496945(PTGES2) 116496961(PTGES) 116499986(PTGES3)
TGU100220496(PTGES2) 100226316(PTGES) 105759550(PTGES3)
LSR110477079(PTGES3) 110482265(PTGES) 110482285(PTGES2)
SCAN103819006(PTGES) 103819032(PTGES2) 103825032(PTGES3)
PMOA120499454(PTGES3) 120507400(PTGES2) 120507455(PTGES)
OTC121336766(PTGES3) 121337047(PTGES) 121337069(PTGES2)
PRUF121356371(PTGES3) 121357608(PTGES) 121357622(PTGES2)
GFR102032881(PTGES2) 102036845(PTGES3) 102043180(PTGES)
FAB101814687(PTGES) 101815630(PTGES3) 101819252(PTGES2)
PHI102107000(PTGES2) 102112688(PTGES) 102113406(PTGES3)
PMAJ107198604(PTGES3) 107212071(PTGES) 107212232(PTGES2)
CCAE111936994(PTGES) 111940580(PTGES3) 111944650(PTGES2)
CCW104688295(PTGES) 104688461(PTGES2)
CBRC103611892(PTGES3) 103623161(PTGES) 103623281(PTGES2)
ETL114054509(PTGES) 114054536(PTGES2) 114071121(PTGES3)
ZAB102060938(PTGES) 102071013(PTGES2) 106630566(PTGES3)
ACHL103806575(PTGES3) 103807105(PTGES) 103812135(PTGES2)
FPG101911860(PTGES3) 101912147(PTGES) 101913364(PTGES2)
FCH102054668(PTGES3) 102054786(PTGES) 102056145(PTGES2)
CLV102083579(PTGES3) 102088657(PTGES) 102095294(PTGES2)
EGZ104122567(PTGES2) 104128929(PTGES3) 104129811(PTGES)
NNI104015917(PTGES3) 104023142(PTGES2) 104023161(PTGES)
PLET104615038(PTGES2) 104618532 104620087(PTGES3)
PCRI104025205(PTGES2) 104037998(PTGES3) 104038712(PTGES)
ACUN113486551(PTGES) 113486564(PTGES2) 113490709(PTGES3)
TALA104357785(PTGES) 104360667(PTGES2) 104361703(PTGES3)
PADL103915291(PTGES) 103915309(PTGES2) 103925450(PTGES3)
ACHC115334768(PTGES2) 115335135(PTGES) 115351363(PTGES3)
HALD104311857(PTGES2) 104317838(PTGES3) 104318488(PTGES)
CCRI104155978(PTGES2) 104158015(PTGES) 104163290(PTGES3)
CSTI104551044(PTGES2) 104556948(PTGES3) 104557498(PTGES)
EHS104504010(PTGES2) 104504919(PTGES3) 104514922(PTGES)
CMAC104474259(PTGES2) 104479760(PTGES)
MUI104535478(PTGES3) 104536864(PTGES) 104545595(PTGES2)
FGA104071654(PTGES3) 104080520(PTGES) 104081608(PTGES2)
GSTE104251899(PTGES2) 104252548(PTGES3) 104253397(PTGES)
LDI104340936(PTGES2) 104344294(PTGES3) 104351320(PTGES)
MNB103770633(PTGES2) 103773799(PTGES) 103779802(PTGES3)
OHA104329260(PTGES) 104329432(PTGES2) 104332888(PTGES3)
AAM106482115(PTGES3) 106486076(PTGES) 106495192
AROW112961794(PTGES3) 112963034(PTGES2)
NPD112954133(PTGES3) 112955983(PTGES) 112956026(PTGES2)
DNE112984177(PTGES) 112989539(PTGES2) 112994732(PTGES3)
ASN102372152(PTGES2) 102380942(PTGES3) 102385675(PTGES)
AMJ102568009(PTGES3) 102572117(PTGES) 102572564(PTGES2)
CPOO109313907(PTGES2) 109313936(PTGES) 109324445(PTGES3)
GGN109292731(PTGES2) 109292951(PTGES) 109293232(PTGES3)
PSS102449946(PTGES) 102458388(PTGES3) 102462899(PTGES2)
CMY102942542(PTGES3) 102946455(PTGES2) 102946468(PTGES)
CPIC101932786(PTGES2) 101941196(PTGES) 101945250(PTGES3)
TST117867132(PTGES2) 117889544(PTGES)
CABI116827727(PTGES3) 116835205(PTGES2) 116835211(PTGES)
MRV120386896(PTGES) 120391056(PTGES3)
ACS100556359(ptges) 100559049(ptges3) 100563447(ptges2)
PVT110075035(PTGES3) 110078810(PTGES2) 110079584(PTGES)
SUND121922607(PTGES3) 121936616(PTGES2) 121936993(PTGES)
PBI103062249(PTGES) 103063196(PTGES2) 103068049(PTGES3)
PMUR107293518(PTGES) 107293739(PTGES3) 107295891(PTGES2)
TSR106538416(PTGES) 106545326(PTGES3) 106554132(PTGES2)
PGUT117662726(PTGES3) 117676567(PTGES) 117678049(PTGES2)
VKO123019196(PTGES3) 123028180(PTGES2) 123035226(PTGES)
PMUA114589026(PTGES2) 114589329(PTGES) 114592976(PTGES3)
ZVI118076598(PTGES3) 118083944(PTGES) 118084141(PTGES2)
GJA107120895(PTGES3) 107123252(PTGES2)
STOW125429132(PTGES3) 125442224(PTGES2)
XLA100037123(ptges2.L) 108699947 108699960(ptges2.S) 108704691(ptges.L) 108709846 380300(ptges3.L)
XTR100038070(ptges2) 100038203(ptges) 492275(ptges3)
NPR108792685(PTGES) 108794462(PTGES2) 108797893(PTGES3)
RTEM120914152(PTGES) 120914190(PTGES2) 120929503(PTGES3)
BBUF120977063(PTGES2) 120977285(PTGES) 120996021(PTGES3)
BGAR122931565(PTGES3) 122946201(PTGES2) 122946733(PTGES)
DRE406449(ptges3a) 415227(ptges3b) 544666(ptges) 799964(ptgesl)
SRX107705749 107710751 107711885 107716195 107724867 107726289 107745455 107750889
SANH107667550 107667902 107668559 107673275 107691017 107693847 107695820 107697015
SGH107570321 107571786 107579680 107587481 107598231 107600004 107601352 107602856
CCAR109057486 109058952 109062555 109067529 109084235 109084262 109090662(ptges)
CAUA113041049 113049387 113065460 113070279 113070530 113071972 113075803 113107674
PPRM120463668(ptges3a) 120469305(ptges) 120478155(ptges3b) 120484911(ptgesl)
MAMB125260102(ptges3b) 125260178(ptges3a) 125267140(ptges) 125279682(ptgesl)
IPU100528333(ptges3a) 108259917(ptges) 108265283(ptgesl)
PHYP113530837(ptges3) 113531653(ptges) 113535245(ptges2)
SMEO124379531(ptges) 124399454(ptgesl)
TFD113649402(ptgesl) 113655188(ptges) 113658339(ptges3a)
AMEX103024258 103037656 103045893(ptges)
EEE113570170(ptges) 113584445(ptges3) 113590363(ptges2) 113591471
TRU101067534(ptges3) 101068061 101075005(ptges) 101078041(ptges2)
TNGGSTEN00014379G001 GSTEN00028131G001 GSTEN00031003G001
LCO104919638(ptges3) 104932932 104935142(ptges) 109141570(ptges2)
NCC104942164(ptges) 104951667(ptges3) 104967534
CGOB115010663 115010723(ptges3) 115013905(ptges2) 115016754(ptges)
ELY117251941(ptgesl) 117257650(ptges3a) 117258911 117269424(ptges)
EFO125890689(ptgesl) 125891700(ptges3a) 125891713(ptges3b) 125906203(ptges)
PLEP121944512(ptgesl) 121946797(ptges3b) 121946894(ptges3a) 121959890(ptges)
SLUC116039402(ptges3a) 116054239(ptgesl) 116062182(ptges3b) 116062996(ptges)
ECRA117945423(ptgesl) 117947802(ptges3a) 117947983 117959881(ptges)
ESP116689173(ptges2) 116692038 116693063(ptges3) 116704503(ptges)
PFLV114555520(ptges2) 114558438(ptges3) 114558451 114571001(ptges)
GAT120828890(ptges3b) 120829132(ptges3a) 120830162(ptgesl) 120831559(ptges)
PPUG119222058(ptges3b) 119223517(ptges3a) 119224882(ptgesl) 119226797(ptges)
MSAM119884933 119892254 119900154 119905295 119906061(ptges3a) 119914830(ptges)
CUD121510471(ptgesl) 121517914(ptges3a) 121518116(ptges3b) 121525475(ptges)
ALAT119019773(ptgesl) 119022238(ptges3a) 119023354 119030624(ptges)
MZE101468382(ptges) 101471106 101478781(ptges2) 101482393(ptges3)
ONL100692995(ptges) 100693432(ptges2) 100704884 100706085
OAU116310910(ptges3b) 116316302(ptgesl) 116325854(ptges3a) 116331883(ptges)
OLA101156737(ptges3) 101161606 101162769(ptges) 101163397(ptges2)
OML112158971(ptgesl) 112159301(ptges3b) 112159573(ptges3a) 112163236(ptges)
XMA102220683 102222445(ptges2) 102234359(ptges3) 102237855(ptges)
XCO114144552 114147061(ptges3) 114149168(ptges) 114154701(ptges2)
XHE116724440(ptges3) 116724878(ptges) 116726852 116730432(ptges2)
PRET103467311 103467618(ptges3) 103469837(ptges2) 103473411(ptges)
PFOR103134914(ptges2) 103135925(ptges) 103141173 103147806(ptges3)
PLAI106950875 106955953(ptges2) 106961412(ptges3) 106964895(ptges)
PMEI106914969 106917485(ptges3) 106930106(ptges) 106933318(ptges2)
GAF122828209(ptgesl) 122837536(ptges3a) 122839019(ptges3b) 122846770(ptges)
CVG107081068 107083974 107089752(ptges) 107090268(ptges3) 107095146
CTUL119774091 119782258(ptges3a) 119797440(ptgesl) 119798989(ptges)
GMU124868424(ptges3a) 124872232(ptges) 124873469(ptges3b) 124878641(ptgesl)
NFU107374785(ptges) 107386080(ptges2) 107390842 107391162(ptges3)
KMR108230919(ptges) 108242757(ptgesl) 108244561(ptges3a)
ALIM106516303(ptges) 106521869(ptges2) 106525288 106535591
NWH119413149(ptgesl) 119416803(ptges3b) 119416986(ptges3a) 119424475(ptges)
AOCE111564098(ptges) 111576522 111583794(ptges3) 111585560(ptges2)
MCEP124997134(ptges) 125012225(ptgesl) 125020799(ptges3b) 125024315(ptges3a)
CSEM103384593 103385418(ptges3) 103390083(ptges) 103397398(ptges2)
POV109626131(ptges) 109630504 109635273(ptges3) 109645579(ptges2)
SSEN122770068(ptgesl) 122776658(ptges3a) 122777063(ptges3b) 122787061(ptges)
HHIP117764206(ptges3a) 117764687(ptges3b) 117768478(ptgesl) 117772092(ptges)
HSP118098211(ptges) 118111017(ptges3a) 118111310(ptges3b) 118114606(ptgesl)
LCF108874020(ptges) 108876437 108881627(ptges2) 108900225
SDU111217382(ptges3) 111218973 111237370(ptges) 111238544(ptges2)
SLAL111645677(ptges2) 111668048(ptges) 111670712 111671555(ptges3)
XGL120803287(ptges3a) 120804281(ptges3b) 120805535(ptgesl) 120806029(ptges)
HCQ109515655(ptges2) 109517173(ptges) 109528575 109529379
BPEC110157492(ptges) 110162085(ptges2) 110164609 110164616
MALB109952307(ptges) 109957323(ptges2) 109966035(ptges3) 109970142
BSPL114858188(ptges3b) 114859294(ptges3a) 114861527(ptgesl) 114866494(ptges)
SASA106562718 106566721(TEBP) 106567008(TEBP) 106569712(ptges) 106570430 106571940(TEBP) 106572696(TEBP) 106579969 106585457
OTW112215791 112220065 112220110(ptges) 112221665 112222164 112230767 112232711 112248343(ptgesl)
OMY100136263(tebp) 110491931 110492374 110509513 110523249 110523316(ptges) 110525509(ptgesl) 110532024
OGO124007079 124031726 124032312 124033358(ptgesl) 124045706 124046125(ptges3a) 124047946(ptges) 124047956
ONE115102138 115102668 115111471 115118596 115119082 115120183 115126767 115131912 115139902
SALP111957608 111961862 111966234 111966830 111975185 111976499 111976653 112080614 112080661 112081065(ptges)
SNH120021686 120025924(ptges) 120026017 120059096 120059483 120060179 120060996 120061303 120063144
CCLU121537857(ptges3a) 121538530 121541107 121545437 121551966 121583194 121583204(ptges) 121584723
ELS105014008(ptges3) 105014170(ptges2) 105015294(ptges) 105023832
SFM108918186 108921878(ptges2) 108927254(ptges) 108939438
PKI111837575(ptges3) 111841815(ptges) 111855320 111858662(ptges2)
AANG118207711(ptges3a) 118211766 118212782 118213345(ptges) 118237070(ptgesl)
LOC102690298(ptges) 102697734(ptges3) 102698374(ptges2)
PSPA121298745 121309010 121309683(ptgesl) 121309728(ptges)
ARUT117396656 117396741 117401102 117419288 117422169 117433636 117964674 117966987
LCM102355698(PTGES3) 102356991(PTGES) 102357912 102366765(PTGES2) 102366897(PTGES3L)
CMK103183026(ptgesl) 103183048(ptges) 103189567
RTP109924495 109924567 109925898(ptges3) 109930232(ptges2)
BFO118418361 118420744 118424575
BBEL109478758 109480571 109484551
CIN100175706 100184120
SCLV120337481 120346483
SPU584887
APLC110973355 110976383
SKO100373203 100377537
DMEDmel_CG16817(p23) Dmel_CG4086(Su(P))
DER6544217 6552425
DSE6605987
DSIDsimw501_GD12454(Dsim_Su(P)) Dsimw501_GD18637(Dsim_GD18637)
DYADyak_GE22204 Dyak_GE25973
DAN6493384
DSR110183576 110187939
DPO4802802 4812676
DPE6594317 6601916
DMN108152625 108155117
DWI6645721 6647055
DGR6558109 6563506
DMODmoj_GI16712 Dmoj_GI22609
DAZ108613385
DNV108652468 108654817
DHE111592432 111593316
DVI6622949
CCAT101453804 101456254
BOD106620715 106627670
MDE101891111 101898008
SCAC106092335 106093031
LCQ111678018 111683494
LSQ119602085 119603880
HIS119648755 119659196
AGAAgaP_AGAP004992 AgaP_AGAP011157
ACOZ120953799 120955686
AARA120898344 120901502
ASTE118504237 118511818
AAG5565702 5571046
AALB109411962 109423870
CQUCpipJ_CPIJ003988 CpipJ_CPIJ008199 CpipJ_CPIJ018524
CPII120419540 120423158 120429730
CNS116345880
BCOO119073557 119076155 119085515
AME552470 726977
ACER108000227 108003051
ALAB122711791 122717728
BIM100742036 100743123
BBIF117206380 117211393
BVK117237143 117242847
BVAN117159705 117163619
BTER100645533 100646369
BPYO122572216 122573499
CCAL108626169 108631335
OBB114879826 114880511
MGEN117227597 117228031
NMEA116424630 116426401
CGIG122395982 122397483
SOC105192815 105200510
MPHA105831516 105835251
AEC105145201 105146886
ACEP105617815 105627540
PBAR105424312 105433839
VEM105561790 105568678
HST105187555 105188222
DQU106745971 106748845
CFO105253133 105256356
FEX115235377 115241673
LHU105671234 105680023
PGC109855375 109857063
OBO105281100 105284318
PCF106788551 106791216
PFUC122518112 122525542
VPS122628234 122633566
NVI100114871 100118449
CSOL105365910
TPRE106652860 106657885
MDL103578121 103579155
CGLO123260329 123267209
FAS105265776 105273324
DAM107040477 107041012
AGIF122857045 122857059
LHT122497814
CCIN107263460 107270602
TCA660107 662467
DPA109537452 109541841
SOY115886398 115889905
ATD109598859 109599052
CSET123310965 123321168
AGB108905545 108917060
LDC111504625 111504958
NVL108563748 108568198
APLN108733343 108736908
PPYR116171837 116179977
OTU111427926 111428804
BMOR101746199 101746997 692504
BMAN114243013 114246936 114248180
MSEX115444925 115448537 115455421 119190937 119193293
DPLKGM_206133 KGM_208082 KGM_210949
BANY112043302 112043600 112057818
PMAC106712345 106718162 106719888
PPOT106102846 106104094 106107863
PXU106113619 106117139 106122526
PRAP110992115 110999305 111000112
ZCE119829956 119835655 119838358
HAW110369771 110374580 110380222
HZE124634564 124645027
TNL113492686 113494009 113496536
SLIU111356249 111357144 111360792
OFU114352748 114363247
PXY105386994 105390081 105398014
API100159849 100162234 100569237
DNX107163438 107167298
AGS114121557 114121931
RMD113548456 113561207
BTAB109042966 109044579
DCI103504924 103518727 103518728
CLEC106663520 106667447
HHAL106682163 106684919
NLU111043613 111059177 120356022
PHUPhum_PHUM504110 Phum_PHUM580720
FOC113202563 113204984
TPAL117640582 117653346
ZNE110827943 110837072
CSEC111865120 111871419
FCD110852789 110857024
DPXDAPPUDRAFT_203299 DAPPUDRAFT_56335(PGE2)
DMK116918177 116927470
PVM113803517 113812117 113816960
PJA122257635
PCHN125042171 125044957
HAME121854775 121863234
PCLA123762329 123775310
PTRU123514230 123519714
HAZT108669391 108674826
EAF111696753 111709382 111710929
LSM121114096 121122088
PPOI119103292 119109661 119110470
ISCIscW_ISCW020922
DSV119439734 119443162
RSAN119388302 119393980
RMP119161124 119184969
VDE111246212 111255632
VJA111261169 111268723
TUT107359776 107371159
DPTE113792146 113792626
DFR124494509 124499940
CSCU111618033 111636506
PTEP107439472 107443494 107452338
SDM118186894 118193409
CELCELE_R11A8.5(pges-2) CELE_ZC395.10(daf-41)
CBRCBG_21192 CBG_23755
BMYBM_BM5344(Bma-pges-2) BM_BM7377(Bma-daf-41)
LOALOAG_05032 LOAG_17299
NAINECAME_11884
HROHELRODRAFT_163501 HELRODRAFT_78591
LGILOTGIDRAFT_167297 LOTGIDRAFT_180368
PCAN112564093 112574666
BGT106073550
GAE121384580
HRF124130851 124144770
HRJ124266182 124278829
CRG105330045
MYI110446128 110460100
PMAX117320430 117328204 117344040
MMER123525375
OBI106869621 106879230
OSN115230009
LAK106159270 106176066
SMMSmp_072900.1
OVIT265_08454
EGLEGR_03199
NVE5509381 5515521
EPA110234771
ATEN116299501 116300704
ADF107335869 107340549 107346116 107346122
AMIL114960649 114963376
PDAM113666622 113670399
SPIS111338780 111342224
DGT114518402 114519106
XEN124440370
HMG100211597 105850946
TADTRIADDRAFT_54888 TRIADDRAFT_63654 TRIADDRAFT_63793
AQU100633880 100638237 100640624
ATHAT5G42150
ALY9301639 9329806
CRB17876025
CSAT104720158 104725261 104757648 104760755 104773196
EUSEUTSA_v10027850mg
BRP103848542
BNA106371597 106418718
BOE106293081 106324678
RSZ108806325 108819233 108819600
THJ104798670
CPAP110823093
CIT102613842 102623391
CICCICLE_v10001861mg CICLE_v10008944mg
PVY116140459 116141896
MINC123195572 123203949 123230114
TCC108661126 108661127 18591589 18604340
GRA105770719 105794094
GHI107887034 107905528 107910679 107914077 107957705 107958209
GAB108465018 108479626 108484385
DZI111302115 111311257 111312826 111315167
EGR104423567 104456644 104456645
GMX100775694 100804696 100811576
GSJ114368781 114383905 114389225 114408565 114418674
PVUPHAVU_004G150900g PHAVU_009G009900g
VRA106760982 106766034
VAR108342805 108343811 108344741
VUN114162112 114181248 114181991
CCAJ109799907 109812187 109815676
APRC113865015 113867820
MTRMTR_3g114070 MTR_6g034550 MTR_6g069420
CAM101491202 101496520 101502564
LJALj0g3v0281619.1(Lj0g3v0281619.1) Lj1g3v2195290.1(Lj1g3v2195290.1)
ADU107460172 107475934 107490656
AIP107609879 107626138 107644213
AHF112705656 112712498 112712500 112728520 112751011 112755816 112764560 112776113 112802314
LANG109327973 109340063 109340064 109343074
FVE101301355 101306336
RCN112174528 112176107
PPER18778085 18790528
PMUM103321222 103338692
PAVI110747276 110768327
PDUL117617183 117628786
MDM103428590 103455631
PXB103927599 103946933 103950571
ZJU107409466 107418554
MNT21389543 21399072
CSV101215364 101221439
CMO103488396 103494185
BHJ120070601 120076579
MCHA111006038 111006921 111013903
CMAX111485692 111488954 111496273
CMOS111430142 111444873 111454196 111462967
CPEP111779595 111798052 111798767 111808972
RCU8274697
JCU105635311
HBR110644225 110655905 110660945
MESC110605811 110631033
POP18105559 7464788 7468746 7493490 7493986
PEU105109893 105126941 105133349 105135798 105139884
PALZ118043006 118044253 118046309 118051010 118062008
JRE108980351 109010439
QSU111992816 112013247
QLO115965639 115974523
TWL119980076 119980369 120011552 120017204
VVI100248972 100266342
VRI117904758 117905150 117907922
SLY101268179
SPEN107006052 107015729
SOT102592515 102605251
SSTN125854394
CANN107866862 107867610
NTA107767457 107793601 107794812 107827557 107828701
NSY104223157 104234122 104245539
NTO104084591 104086822 104099631
NAU109215351 109218185 109238891
INI109149491 109153321 109170467
ITR116017666 116027301
SIND105159356 105165991
OEU111375635 111380797 111394443
EGT105956402 105959594
SSPL121801799 121807690
HAN110865894 110869093 110889086 110904532 110937145
ECAD122604085 122609156
LSV111875981 111916341 111917453 111917703 111919496 111919541 122195656
CCAV112502604 112505217 112508528 112520736 112524638
DCR108201791 108225378
CSIN114258580 114259606
BVG104905612
SOE110786347
CQI110720584 110721703
NNU104607421 104609303
MING122072765 122084569
TSS122660198 122661720
PSOM113288953 113291012 113330616 113357187
NCOL116260038 116261466
OSA4335293
DOSAOs04t0244400-01(Os04g0244400)
OBR102708049
BDI100832419
ATS109778852
TDC119352999 119362061
TAES123043383 123051253 123187212
TUA125535339
SBI8069412
ZMA100191300
SITA101778815
SVS117858688
PVIR120673690 120707171
PHAI112896020
PDA103709364 103719592
EGU105033771 105044026
MUS103984552 103995753
DCT110106065 110112866 110116585
PEQ110019487 110020581
AOF109835074 109836195
ATR18436622 18440855
SMOSELMODRAFT_103322 SELMODRAFT_46863
PPP112274648 112296020
CRECHLRE_07g319100v5
VCNVOLCADRAFT_82699
MNGMNEG_1321
CSLCOCSUDRAFT_14039
CVRCHLNCDRAFT_11521 CHLNCDRAFT_139383
APROF751_6209 F751_6760
OLUOSTLU_29981
OTAOT_ostta02g03120 OT_ostta14g01345
BPGBathy12g01980
MISMICPUN_88190
MPPMICPUCDRAFT_5265
CMECYME_CMH214C CYME_CMM110C
GSLGasu_60140 Gasu_64330
CCPCHC_T00007112001
PFJMYCFIDRAFT_123576
BCOMBAUCODRAFT_54166
MBRMONBRDRAFT_8222
SREPTSG_04116
ACANACA1_218450
TGOTGME49_249630 TGME49_304660
TETTTHERM_00945270
PTMGSPATT00036002001
SMINv1.2.021517.t1(symbB.v1.2.021517.t1) v1.2.040178.t1(symbB.v1.2.040178.t1)
FCYFRACYDRAFT_232676
TPSTHAPS_6816
NGDNGA_0073700
AAFAURANDRAFT_23373 AURANDRAFT_31067
PIFPITG_11458
PSOJPHYSODRAFT_332449 PHYSODRAFT_514860
SPARSPRG_02474 SPRG_13907
EHXEMIHUDRAFT_433989 EMIHUDRAFT_443792
GTTGUITHDRAFT_112016 GUITHDRAFT_122806 GUITHDRAFT_161092 GUITHDRAFT_164156
TBRTb927.7.3500
TBGTbgDal_VII3850
TCR506443.70 508265.10
LMALMJF_14_1480
LIFLINJ_14_1580
LDOLDBPK_141580
LMILMXM_14_1480
LBZLBRM_14_1670
LPANLPMP_141480
NGRNAEGRDRAFT_29414 NAEGRDRAFT_62643
TVATVAG_388410
 » show all
Reference
1  [PMID:838703]
  Authors
Ogino N, Miyamoto T, Yamamoto S, Hayaishi O.
  Title
Prostaglandin endoperoxide E isomerase from bovine vesicular gland microsomes, a glutathione-requiring enzyme.
  Journal
J Biol Chem 252:890-5 (1977)
Reference
2  [PMID:3100531]
  Authors
Tanaka Y, Ward SL, Smith WL.
  Title
Immunochemical and kinetic evidence for two different prostaglandin H-prostaglandin E isomerases in sheep vesicular gland microsomes.
  Journal
J Biol Chem 262:1374-81 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 5.3.99.3
IUBMB Enzyme Nomenclature: 5.3.99.3
ExPASy - ENZYME nomenclature database: 5.3.99.3
BRENDA, the Enzyme Database: 5.3.99.3
CAS: 52227-79-9

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