Entry
Name
phosphoglucomutase (glucose-cofactor);
glucose phosphomutase (ambiguous);
glucose-1-phosphate phosphotransferase
Class
Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)
BRITE hierarchy
Sysname
alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)
Reaction(IUBMB)
alpha-D-glucose 1-phosphate = D-glucose 6-phosphate [RN:
R08639 ]
Reaction(KEGG)
Substrate
alpha-D-glucose 1-phosphate [CPD:
C00103 ]
Product
D-glucose 6-phosphate [CPD:
C00092 ]
Comment
The enzyme is activated by D-glucose, which probably acts as an acceptor for a phosphate residue from the substrate, thus being itself converted into the product. cf. EC
5.4.2.2 , phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
History
EC 5.4.2.5 created 1972 as EC 2.7.5.5, transferred 1984 to EC 5.4.2.5
Pathway
ec00520 Amino sugar and nucleotide sugar metabolism
ec01110 Biosynthesis of secondary metabolites
Reference
Authors
FUJIMOTO A, INGRAM P, SMITH RA.
Title
D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6-PHOSPHOTRANSFERASE.
Journal
Reference
2
Authors
Ray WJ Jr, Peck EJ Jr.
Title
Phosphomutases.
Journal
In: Boyer PD (ed). The Enzymes. 3rd ed. Vol. 6. 1972. p. 407-477.
Other DBs
ExplorEnz - The Enzyme Database: 5.4.2.5
ExPASy - ENZYME nomenclature database: 5.4.2.5
BRENDA, the Enzyme Database: 5.4.2.5