KEGG ENZYME: 5.4.3.5

ENZYME: 5.4.3.5

Entry

EC 5.4.3.5                  Enzyme

Name

D-ornithine 4,5-aminomutase;
D-alpha-ornithine 5,4-aminomutase;
D-ornithine aminomutase

Class

Isomerases;
Intramolecular transferases;
Transferring amino groups

Sysname

D-ornithine 4,5-aminomutase

Reaction(IUBMB)

D-ornithine = (2R,4S)-2,4-diaminopentanoate [RN:R02461]

Reaction(KEGG)

R02461

Substrate

D-ornithine [CPD:C00515]

Product

(2R,4S)-2,4-diaminopentanoate [CPD:C03943]

Comment

A pyridoxal-phosphate protein that requires a cobamide cofactor for activity.

History

EC 5.4.3.5 created 1972 as EC 5.4.3.1, transferred 1976 to EC 5.4.3.5, modified 2003

Pathway

ec00470

D-Amino acid metabolism

ec01100

Metabolic pathways

Orthology

K17898

D-ornithine 4,5-aminomutase subunit beta

K17899

D-ornithine 4,5-aminomutase subunit alpha

Genes

MECH:

Q9L42_012465 Q9L42_012470(oraE)

EAV:	EH197_05065 EH197_05070

VCP:	H9L18_06415 H9L18_06420

VHY:	G7082_14515 G7082_14520

FCT:	NRE15_11430 NRE15_11435(oraE)

CSQ:	CSCA_0123 CSCA_0124

CACE:

CACET_c17510(oraS) CACET_c17520(oraE)

CEU:	A7L45_16575 A7L45_16580

CFM:	BJL90_14530 BJL90_14535

CARG:

RSJ17_08690 RSJ17_08695

CDRK:

B9W14_17920 B9W14_17925

CTAG:

LL095_13665 LL095_13670

CALE:

FDN13_03000 FDN13_03005

CALD:

PWK10_08600(oraE) PWK10_08605

CRS:	FQB35_06700 FQB35_06705

CPRF:

K7H06_08985 K7H06_08990

CRAS:

KVH43_11415 KVH43_11420

OCW:	OW730_12725 OW730_12730(oraE)

PROQ:

P6M73_15840(oraE) P6M73_15845

FPLA:

A4U99_15110 A4U99_15115

PETR:

QKW49_11285(oraE) QKW49_11290

DAI:	Desaci_1876 Desaci_1877

AACX:

DEACI_0849 DEACI_0850

ACAE:

HYG86_08055 HYG86_08060

PROM:

QO263_13835(oraE) QO263_13840

EUU:	ADJ67_00780 ADJ67_00785

VGU:	HYG85_19065 HYG85_19070

VPY:	HZI73_17660 HZI73_17665

AMIJ:

EQM06_12580 EQM06_12585

AMIC:

Ami3637_07705 Ami3637_07710

ABUT:

Ami103574_00575 Ami103574_00580

ETM:	CE91St48_39700(oraE) CE91St48_39710(oraS)

AMT:	Amet_2370 Amet_2371

AOE:	Clos_1695 Clos_1696

GFE:	Gferi_26745 Gferi_26750

CSPO:

QNI18_08940 QNI18_08945(oraE)

CDF:	CD630_04450(oraS) CD630_04460(oraE)

PDC:	CDIF630_00573(oraS) CDIF630_00574(oraE)

CDC:	CD196_0402(oraS) CD196_0403(oraE)

CDL:	CDR20291_0388(oraS) CDR20291_0389(oraE)

PDF:	CD630DERM_04450(oraS) CD630DERM_04460(oraE)

RHOM:

FRIFI_0797 FRIFI_0798

TEM:	JW646_03930 JW646_03935

TGC:	L0P85_04340 L0P85_04345(oraE)

TMY:	TEMA_40320(oraS) TEMA_40330(oraE)

TPET:

TPHSE_10720(oraS) TPHSE_10730(oraE)

TEB:	T8CH_0876(oraS) T8CH_0877(oraE)

THYR:

P4S50_12685(oraE) P4S50_12690

CST:	CLOST_1290(oraE) CLOST_1291(oraS)

TTE:	TTE1237 TTE1238(Sbm3)

TEX:	Teth514_1480 Teth514_1481

THX:	Thet_1422 Thet_1423

TPD:	Teth39_1043 Teth39_1044

TBO:	Thebr_1070 Thebr_1071

TWI:	Thewi_1187 Thewi_1188

THEZ:

OEI98_001238 OEI98_001239(oraE)

TOC:	Toce_1485 Toce_1486

NTH:	Nther_1169 Nther_1170

NCD:	ACONDI_00603(oraS) ACONDI_00604(oraE)

HOR:	Hore_21070 Hore_21080

AFT:	BBF96_13580 BBF96_13585

KME:	H0A61_00507(oraE) H0A61_00508(oraS)

HPRF:

HLPR_14350(oraE) HLPR_14360

SPOA:

EQM13_10945 EQM13_10950

KPAR:

JL105_07120 JL105_07125

CAZO:

G3A45_03825 G3A45_03830

TIZ:	RBU61_10260(oraE) RBU61_10265

SEDZ:

JYG23_00925 JYG23_00930

PFT:	JBW_01655 JBW_01656

FCZ:	IMF26_05965 IMF26_05970

MANR:

MPAN_008590(oraS) MPAN_008600(oraE)

MBJ:	KQ51_00243(oraE) KQ51_00244(oraS)

XCL:	G4Z02_05190 G4Z02_05195

TBK:	HF295_00030 HF295_00035

TBM:	BK010_05540 BK010_05545

TBZ:	BK011_05580 BK011_05585

ARS:	ADJ73_08375 ADJ73_08380

PAC:	PPA2279 PPA2280

PAK:	HMPREF0675_5356 HMPREF0675_5357

PAV:	TIA2EST22_11175 TIA2EST22_11180

PAX:	TIA2EST36_11150 TIA2EST36_11155

PAZ:	TIA2EST2_11095 TIA2EST2_11100

PAW:	PAZ_c23770 PAZ_c23780

PAD:	TIIST44_04215 TIIST44_04220

PCN:	TIB1ST10_11615 TIB1ST10_11620

PACC:

PAC1_11625 PAC1_11630

PACH:

PAGK_2188

PACN:

TIA1EST1_11245 TIA1EST1_11250

CACN:

RN83_00025 RN83_00030

PRA:	PALO_10895

PRL:	BCB70_06940 BCB70_06945

CGRN:

4412665_00380 4412665_00381

CEQU:

O6R08_10905(oraS) O6R08_10910(oraE)

PAUS:

NCTC13651_02408 NCTC13651_02409

PPC:	HMPREF9154_0895 HMPREF9154_0896

ARUB:

J5A65_10515 J5A65_10520

PROP:

QQ658_14550(oraS) QQ658_14555(oraE)

ABAT:

CFX1CAM_0748(oraS) CFX1CAM_0749(oraE)

TPI:	TREPR_1360 TREPR_1361

SLR:	L21SP2_1021 L21SP2_1022

MSIL:

METEAL_10810(oraE) METEAL_10820(oraS)

FHW:	RN87_08660 RN87_08665

FPD:	CTM68_09140 CTM68_09145

FCI:	I6I83_05745 I6I83_05750

RHOZ:

GXP67_19605

TME:	Tmel_0908 Tmel_0909

TAF:	THA_1163 THA_1164

THP:	BG95_05280 BG95_05285

THER:

Y592_05360 Y592_05365

TFE:	JYK00_04215 JYK00_04220

FNO:	Fnod_1642 Fnod_1643

FPE:	Ferpe_1993 Ferpe_1994

FIA:	NA23_09990 NA23_09995(oraE)

FRR:	IB67_00410 IB67_00415

OCY:	OSSY52_03930(oraS) OSSY52_03940(oraE)

PMO:	Pmob_1169 Pmob_1170

MPZ:	Marpi_1536 Marpi_1537

MARN:

LN42_08185 LN42_08190

MAEO:

JRV97_04075 JRV97_04080

DTN:	DTL3_0762 DTL3_0763(oraE)

OCS:	OF820_07995(oraE) OF820_08000

KOL:	Kole_0359 Kole_0360

KPF:	IX53_10205 IX53_10210

MPG:	Theba_1254 Theba_1255

MINF:

MESINF_2280(oraE) MESINF_2281(oraS)

ASAC:

ATHSA_0993 ATHSA_0994

» show all

Reference

1 [PMID:4711468]

Authors

Somack R, Costilow RN.

Title

Purification and properties of a pyridoxal phosphate and coenzyme B 12 dependent D- -ornithine 5,4-aminomutase.

Journal

Biochemistry 12:2597-604 (1973)
DOI:10.1021/bi00738a008

Sequence

[cst:CLOST_1290 CLOST_1291]

Other DBs

ExplorEnz - The Enzyme Database:

5.4.3.5

IUBMB Enzyme Nomenclature:

5.4.3.5

ExPASy - ENZYME nomenclature database:

5.4.3.5

BRENDA, the Enzyme Database:

5.4.3.5

CAS:	62213-30-3

DBGET integrated database retrieval system